Fluorine in PDB 8g4o: Native Gaba-A Receptor From the Mouse Brain, ALPHA1-BETA2-GAMMA2 Subtype, in Complex with Didesethylflurazepam and Endogenous Gaba

The structure of Native Gaba-A Receptor From the Mouse Brain, ALPHA1-BETA2-GAMMA2 Subtype, in Complex with Didesethylflurazepam and Endogenous Gaba also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Fluorine atom in the Native Gaba-A Receptor From the Mouse Brain, ALPHA1-BETA2-GAMMA2 Subtype, in Complex with Didesethylflurazepam and Endogenous Gaba (pdb code 8g4o). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Native Gaba-A Receptor From the Mouse Brain, ALPHA1-BETA2-GAMMA2 Subtype, in Complex with Didesethylflurazepam and Endogenous Gaba, PDB code: 8g4o:

Fluorine binding site 1 out of 1 in the Native Gaba-A Receptor From the Mouse Brain, ALPHA1-BETA2-GAMMA2 Subtype, in Complex with Didesethylflurazepam and Endogenous Gaba


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Native Gaba-A Receptor From the Mouse Brain, ALPHA1-BETA2-GAMMA2 Subtype, in Complex with Didesethylflurazepam and Endogenous Gaba within 5.0Å range: probe atom residue distance (Å) B Occ C:F601 b:117.1 occ:1.00 F02 C:YNL601 0.0 117.1 1.0 C19 C:YNL601 1.3 109.6 1.0 C21 C:YNL601 2.4 104.5 1.0 C16 C:YNL601 2.4 105.0 1.0 C10 C:YNL601 2.9 104.7 1.0 C08 C:YNL601 2.9 104.2 1.0 C15 C:YNL601 3.1 104.0 1.0 CG1 C:VAL202 3.3 93.3 1.0 CE1 C:HIS101 3.4 91.0 1.0 C20 C:YNL601 3.6 102.2 1.0 C23 C:YNL601 3.6 103.5 1.0 C07 C:YNL601 3.7 109.9 1.0 ND1 C:HIS101 3.8 92.8 1.0 C18 C:YNL601 4.0 108.6 1.0 N05 C:YNL601 4.0 108.8 1.0 C22 C:YNL601 4.1 103.0 1.0 CB C:VAL202 4.2 90.2 1.0 CB C:SER204 4.3 108.6 1.0 CD2 C:TYR209 4.3 94.1 1.0 N04 C:YNL601 4.4 116.9 1.0 NE2 C:HIS101 4.4 90.9 1.0 C13 C:YNL601 4.5 110.6 1.0 C14 C:YNL601 4.5 108.1 1.0 C17 C:YNL601 4.6 107.8 1.0 CB C:TYR209 4.7 97.7 1.0 CG C:TYR209 4.8 89.8 1.0 CG2 C:VAL202 4.8 97.2 1.0 OG C:SER204 4.8 112.5 1.0 C11 C:YNL601 4.9 117.2 1.0 CE2 C:TYR209 5.0 97.1 1.0

C.Sun, H.Zhu, S.Clark, E.Gouaux. Cryo-Em Structures Reveal Native Gabaa Receptor Assemblies and Pharmacology Nature 2023.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-023-06556-W