Fluorine in PDB 8gd4: Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 Complexed with Dmfo Inhibitor 6
Protein crystallography data
The structure of Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 Complexed with Dmfo Inhibitor 6, PDB code: 8gd4
was solved by
P.R.Watson,
A.D.Craigin,
D.W.Christianson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 29.56 / 2.00 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 74.803, 92.364, 96.474, 90, 90, 90 |
| R / Rfree (%) | 18.5 / 22.2 |
Other elements in 8gd4:
The structure of Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 Complexed with Dmfo Inhibitor 6 also contains other interesting chemical elements:
| Potassium | (K) | 4 atoms |
| Zinc | (Zn) | 2 atoms |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 Complexed with Dmfo Inhibitor 6
(pdb code 8gd4). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 Complexed with Dmfo Inhibitor 6, PDB code: 8gd4:
Jump to Fluorine binding site number: 1; 2; 3; 4;
In total 4 binding sites of Fluorine where determined in the Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 Complexed with Dmfo Inhibitor 6, PDB code: 8gd4:
Jump to Fluorine binding site number: 1; 2; 3; 4;
Fluorine binding site 1 out of 4 in 8gd4
Go back to
Fluorine Binding Sites List in 8gd4
Fluorine binding site 1 out
of 4 in the Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 Complexed with Dmfo Inhibitor 6
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 Complexed with Dmfo Inhibitor 6 within 5.0Å range:
|
Fluorine binding site 2 out of 4 in 8gd4
Go back to
Fluorine Binding Sites List in 8gd4
Fluorine binding site 2 out
of 4 in the Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 Complexed with Dmfo Inhibitor 6
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 Complexed with Dmfo Inhibitor 6 within 5.0Å range:
|
Fluorine binding site 3 out of 4 in 8gd4
Go back to
Fluorine Binding Sites List in 8gd4
Fluorine binding site 3 out
of 4 in the Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 Complexed with Dmfo Inhibitor 6
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 Complexed with Dmfo Inhibitor 6 within 5.0Å range:
|
Fluorine binding site 4 out of 4 in 8gd4
Go back to
Fluorine Binding Sites List in 8gd4
Fluorine binding site 4 out
of 4 in the Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 Complexed with Dmfo Inhibitor 6
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Crystal Structure of Danio Rerio Histone Deacetylase 6 Catalytic Domain 2 Complexed with Dmfo Inhibitor 6 within 5.0Å range:
|
Reference:
B.Konig,
P.R.Watson,
N.Rebing,
A.D.Craigin,
L.Schaker-Hubner,
D.W.Christianson,
F.K.Hansen.
Difluoromethyl-1,3,4-Oxadiazoles Are Selective, Mechanism-Based, and Essentially Irreversible Inhibitors of Histone Deacetylase 6 To Be Published.
Page generated: Fri Aug 2 19:46:05 2024
Last articles
Zn in 9MJ5Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
