Fluorine in PDB 8gwm: Sars-Cov-2 E-Rtc Bound with Mmp-NSP9 and Gmppnp

All present enzymatic activity of Sars-Cov-2 E-Rtc Bound with Mmp-NSP9 and Gmppnp:
2.7.7.48;

The structure of Sars-Cov-2 E-Rtc Bound with Mmp-NSP9 and Gmppnp also contains other interesting chemical elements:

Zinc

(Zn)

8 atoms

The binding sites of Fluorine atom in the Sars-Cov-2 E-Rtc Bound with Mmp-NSP9 and Gmppnp (pdb code 8gwm). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Sars-Cov-2 E-Rtc Bound with Mmp-NSP9 and Gmppnp, PDB code: 8gwm:

Fluorine binding site 1 out of 1 in the Sars-Cov-2 E-Rtc Bound with Mmp-NSP9 and Gmppnp


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Sars-Cov-2 E-Rtc Bound with Mmp-NSP9 and Gmppnp within 5.0Å range: probe atom residue distance (Å) B Occ G:F201 b:67.3 occ:1.00 F G:6GS201 0.0 67.3 1.0 C2' G:6GS201 1.4 67.3 1.0 C2M G:6GS201 2.3 67.3 1.0 C3' G:6GS201 2.4 67.3 1.0 C1' G:6GS201 2.4 67.3 1.0 O A:LEU49 2.9 28.1 1.0 O3' G:6GS201 3.2 67.3 1.0 O2 G:6GS201 3.3 67.3 1.0 O4' G:6GS201 3.4 67.3 1.0 C4' G:6GS201 3.4 67.3 1.0 N1 G:6GS201 3.4 67.3 1.0 C A:LEU49 3.5 26.8 1.0 C2 G:6GS201 3.8 67.3 1.0 CB A:PHE48 3.9 17.1 1.0 N A:LEU49 3.9 20.4 1.0 N A:LYS50 4.1 29.8 1.0 CA A:LYS50 4.2 36.1 1.0 CA A:LEU49 4.4 23.0 1.0 C5' G:6GS201 4.5 67.3 1.0 C6 G:6GS201 4.5 67.3 1.0 CE2 A:PHE35 4.5 26.3 1.0 C A:PHE48 4.7 19.1 1.0 CG A:PHE48 4.8 15.5 1.0 CA A:PHE48 4.9 17.6 1.0 CZ A:PHE35 4.9 44.0 1.0 CD2 A:PHE35 5.0 22.1 1.0 CB A:LYS50 5.0 40.7 1.0

L.Yan, Y.Huang, J.Ge, Z.Liu, P.Lu, B.Huang, S.Gao, J.Wang, L.Tan, S.Ye, F.Yu, W.Lan, S.Xu, F.Zhou, L.Shi, L.W.Guddat, Y.Gao, Z.Rao, Z.Lou. A Mechanism For Sars-Cov-2 Rna Capping and Its Inhibition By Nucleotide Analog Inhibitors. Cell V. 185 4347 2022.
ISSN: ISSN 1097-4172
PubMed: 36335936
DOI: 10.1016/J.CELL.2022.09.037