Fluorine in PDB 8hkq: Ion Channel

The structure of Ion Channel also contains other interesting chemical elements:

Sodium	(Na)	1 atom
Potassium	(K)	11 atoms
Zinc	(Zn)	4 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 12;

Binding sites:

The binding sites of Fluorine atom in the Ion Channel (pdb code 8hkq). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 12 binding sites of Fluorine where determined in the Ion Channel, PDB code: 8hkq:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Fluorine binding site 1 out of 12 in the Ion Channel


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Ion Channel within 5.0Å range: probe atom residue distance (Å) B Occ D:F1301 b:20.0 occ:1.00 F01 D:LQ91301 0.0 20.0 1.0 C23 D:LQ91301 1.4 20.0 1.0 F03 D:LQ91301 2.2 20.0 1.0 F02 D:LQ91301 2.2 20.0 1.0 C19 D:LQ91301 2.4 20.0 1.0 N09 D:LQ91301 2.8 20.0 1.0 SG D:CYS308 2.8 69.5 1.0 CA D:GLY285 3.2 71.3 1.0 CG D:MET334 3.5 72.2 1.0 C18 D:LQ91301 3.6 20.0 1.0 C D:GLY285 3.8 71.2 1.0 CB D:CYS308 3.9 65.8 1.0 N08 D:LQ91301 4.2 20.0 1.0 N D:GLY285 4.2 69.7 1.0 O D:GLY285 4.3 69.8 1.0 N D:THR286 4.3 70.2 1.0 O D:LEU281 4.5 76.4 1.0 C14 D:LQ91301 4.5 20.0 1.0 CB D:MET334 4.5 72.3 1.0 CA D:CYS308 4.6 62.5 1.0 SD D:MET334 4.7 83.2 1.0 O D:VAL282 4.8 72.6 1.0 O D:CYS308 4.9 63.2 1.0

Fluorine binding site 2 out of 12 in the Ion Channel


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Ion Channel within 5.0Å range: probe atom residue distance (Å) B Occ D:F1301 b:20.0 occ:1.00 F02 D:LQ91301 0.0 20.0 1.0 C23 D:LQ91301 1.4 20.0 1.0 CG D:MET334 1.5 72.2 1.0 F01 D:LQ91301 2.2 20.0 1.0 F03 D:LQ91301 2.2 20.0 1.0 CB D:MET334 2.3 72.3 1.0 C19 D:LQ91301 2.4 20.0 1.0 N09 D:LQ91301 3.2 20.0 1.0 SD D:MET334 3.2 83.2 1.0 C18 D:LQ91301 3.3 20.0 1.0 CA D:MET334 3.6 71.9 1.0 CE D:MET334 3.9 73.7 1.0 C D:MET334 4.0 71.3 1.0 CA D:GLY285 4.1 71.3 1.0 N08 D:LQ91301 4.3 20.0 1.0 O D:MET334 4.3 71.2 1.0 C14 D:LQ91301 4.3 20.0 1.0 N D:ILE335 4.4 69.7 1.0 N D:MET334 4.7 69.0 1.0 O D:LEU330 4.8 78.2 1.0 O D:VAL331 4.8 71.2 1.0 SG D:CYS308 4.9 69.5 1.0 N D:GLY285 5.0 69.7 1.0

Fluorine binding site 3 out of 12 in the Ion Channel


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Ion Channel within 5.0Å range: probe atom residue distance (Å) B Occ D:F1301 b:20.0 occ:1.00 F03 D:LQ91301 0.0 20.0 1.0 C23 D:LQ91301 1.4 20.0 1.0 F01 D:LQ91301 2.2 20.0 1.0 F02 D:LQ91301 2.2 20.0 1.0 C19 D:LQ91301 2.4 20.0 1.0 C18 D:LQ91301 2.8 20.0 1.0 N09 D:LQ91301 3.6 20.0 1.0 CG D:MET334 3.7 72.2 1.0 SG D:CYS308 3.9 69.5 1.0 CG2 D:THR311 3.9 59.1 1.0 CB D:MET334 4.0 72.3 1.0 C14 D:LQ91301 4.2 20.0 1.0 CG2 D:VAL331 4.4 73.4 1.0 N08 D:LQ91301 4.5 20.0 1.0 CA D:VAL331 4.7 71.1 1.0 CE2 D:PHE307 4.8 67.6 1.0 O D:VAL331 4.8 71.2 1.0 CA D:GLY285 4.9 71.3 1.0 CB D:CYS308 4.9 65.8 1.0 CB D:VAL331 5.0 73.0 1.0 CA D:CYS308 5.0 62.5 1.0 CG2 D:ILE289 5.0 77.8 1.0

Fluorine binding site 4 out of 12 in the Ion Channel


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Ion Channel within 5.0Å range: probe atom residue distance (Å) B Occ A:F1301 b:20.0 occ:1.00 F01 A:LQ91301 0.0 20.0 1.0 C23 A:LQ91301 1.4 20.0 1.0 F03 A:LQ91301 2.2 20.0 1.0 F02 A:LQ91301 2.2 20.0 1.0 C19 A:LQ91301 2.4 20.0 1.0 SG A:CYS308 2.8 69.4 1.0 N09 A:LQ91301 2.8 20.0 1.0 CA A:GLY285 3.3 73.2 1.0 C18 A:LQ91301 3.6 20.0 1.0 CG A:MET334 3.6 73.5 1.0 CB A:CYS308 3.8 64.8 1.0 C A:GLY285 3.9 73.3 1.0 N08 A:LQ91301 4.2 20.0 1.0 N A:GLY285 4.3 73.1 1.0 CA A:CYS308 4.4 64.1 1.0 O A:GLY285 4.4 73.9 1.0 O A:LEU281 4.5 77.8 1.0 N A:THR286 4.5 68.6 1.0 C14 A:LQ91301 4.5 20.0 1.0 CE A:MET334 4.6 74.2 1.0 CB A:MET334 4.6 73.4 1.0 O A:CYS308 4.7 64.1 1.0 SD A:MET334 4.9 84.0 1.0 CG2 A:THR311 4.9 59.4 1.0 O A:VAL282 4.9 71.4 1.0 C A:CYS308 5.0 63.0 1.0

Fluorine binding site 5 out of 12 in the Ion Channel


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Ion Channel within 5.0Å range: probe atom residue distance (Å) B Occ A:F1301 b:20.0 occ:1.00 F02 A:LQ91301 0.0 20.0 1.0 C23 A:LQ91301 1.4 20.0 1.0 CG A:MET334 1.6 73.5 1.0 F03 A:LQ91301 2.2 20.0 1.0 F01 A:LQ91301 2.2 20.0 1.0 C19 A:LQ91301 2.4 20.0 1.0 CB A:MET334 2.5 73.4 1.0 N09 A:LQ91301 3.2 20.0 1.0 C18 A:LQ91301 3.3 20.0 1.0 SD A:MET334 3.3 84.0 1.0 CE A:MET334 3.6 74.2 1.0 CA A:MET334 3.7 71.5 1.0 C A:MET334 3.9 71.0 1.0 CA A:GLY285 4.1 73.2 1.0 O A:MET334 4.2 70.9 1.0 N08 A:LQ91301 4.3 20.0 1.0 C14 A:LQ91301 4.3 20.0 1.0 N A:ILE335 4.4 70.4 1.0 SG A:CYS308 4.8 69.4 1.0 N A:MET334 4.9 68.7 1.0 O A:VAL331 4.9 68.5 1.0 N A:GLY285 4.9 73.1 1.0 O A:LEU281 5.0 77.8 1.0

Fluorine binding site 6 out of 12 in the Ion Channel


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Ion Channel within 5.0Å range: probe atom residue distance (Å) B Occ A:F1301 b:20.0 occ:1.00 F03 A:LQ91301 0.0 20.0 1.0 C23 A:LQ91301 1.4 20.0 1.0 F01 A:LQ91301 2.2 20.0 1.0 F02 A:LQ91301 2.2 20.0 1.0 C19 A:LQ91301 2.4 20.0 1.0 C18 A:LQ91301 2.8 20.0 1.0 N09 A:LQ91301 3.6 20.0 1.0 CG A:MET334 3.7 73.5 1.0 SG A:CYS308 3.9 69.4 1.0 CG2 A:THR311 3.9 59.4 1.0 CB A:MET334 4.0 73.4 1.0 C14 A:LQ91301 4.2 20.0 1.0 N08 A:LQ91301 4.5 20.0 1.0 CG2 A:VAL331 4.6 71.5 1.0 CA A:VAL331 4.7 70.0 1.0 O A:VAL331 4.7 68.5 1.0 CE2 A:PHE307 4.8 65.8 1.0 CB A:CYS308 5.0 64.8 1.0 CA A:CYS308 5.0 64.1 1.0 CA A:GLY285 5.0 73.2 1.0 CG1 A:VAL331 5.0 68.1 1.0

Fluorine binding site 7 out of 12 in the Ion Channel


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of Ion Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:F1301 b:20.0 occ:1.00 F01 C:LQ91301 0.0 20.0 1.0 C23 C:LQ91301 1.4 20.0 1.0 F03 C:LQ91301 2.2 20.0 1.0 F02 C:LQ91301 2.2 20.0 1.0 SG C:CYS308 2.3 70.1 1.0 C19 C:LQ91301 2.4 20.0 1.0 CB C:CYS308 3.2 66.1 1.0 N09 C:LQ91301 3.2 20.0 1.0 C18 C:LQ91301 3.3 20.0 1.0 CA C:CYS308 3.4 65.0 1.0 CG2 C:THR311 3.7 59.0 1.0 O C:CYS308 3.9 65.3 1.0 C C:CYS308 4.1 64.2 1.0 N08 C:LQ91301 4.3 20.0 1.0 CA C:GLY285 4.3 70.2 1.0 C14 C:LQ91301 4.4 20.0 1.0 C C:GLY285 4.5 71.0 1.0 CE2 C:PHE307 4.5 65.7 1.0 N C:CYS308 4.6 64.0 1.0 CG C:MET334 4.6 70.9 1.0 O C:GLY285 4.8 70.3 1.0 CD2 C:PHE307 4.9 63.0 1.0 N C:THR286 5.0 70.2 1.0

Fluorine binding site 8 out of 12 in the Ion Channel


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of Ion Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:F1301 b:20.0 occ:1.00 F02 C:LQ91301 0.0 20.0 1.0 C23 C:LQ91301 1.4 20.0 1.0 F03 C:LQ91301 2.2 20.0 1.0 F01 C:LQ91301 2.2 20.0 1.0 C19 C:LQ91301 2.3 20.0 1.0 CG C:MET334 2.4 70.9 1.0 N09 C:LQ91301 2.9 20.0 1.0 CA C:GLY285 3.3 70.2 1.0 CB C:MET334 3.4 71.9 1.0 C18 C:LQ91301 3.6 20.0 1.0 SD C:MET334 3.7 81.7 1.0 SG C:CYS308 3.7 70.1 1.0 CE C:MET334 4.1 73.8 1.0 C C:GLY285 4.2 71.0 1.0 N08 C:LQ91301 4.2 20.0 1.0 N C:GLY285 4.3 69.8 1.0 C14 C:LQ91301 4.5 20.0 1.0 O C:GLY285 4.5 70.3 1.0 O C:LEU281 4.6 79.0 1.0 CA C:MET334 4.7 72.0 1.0 CB C:CYS308 4.9 66.1 1.0 N C:THR286 5.0 70.2 1.0

Fluorine binding site 9 out of 12 in the Ion Channel


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of Ion Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:F1301 b:20.0 occ:1.00 F03 C:LQ91301 0.0 20.0 1.0 C23 C:LQ91301 1.4 20.0 1.0 F01 C:LQ91301 2.2 20.0 1.0 F02 C:LQ91301 2.2 20.0 1.0 C19 C:LQ91301 2.4 20.0 1.0 C18 C:LQ91301 2.8 20.0 1.0 CG C:MET334 3.6 70.9 1.0 N09 C:LQ91301 3.6 20.0 1.0 CB C:MET334 3.7 71.9 1.0 CG2 C:THR311 4.1 59.0 1.0 C14 C:LQ91301 4.1 20.0 1.0 SG C:CYS308 4.2 70.1 1.0 CA C:VAL331 4.3 69.6 1.0 O C:VAL331 4.4 70.9 1.0 N08 C:LQ91301 4.5 20.0 1.0 CG2 C:VAL331 4.5 72.3 1.0 CG1 C:VAL331 4.6 67.5 1.0 CB C:VAL331 4.7 70.3 1.0 CG1 C:ILE335 4.8 71.8 1.0 C C:VAL331 4.9 70.1 1.0 N C:ILE335 4.9 68.9 1.0 CE2 C:PHE307 4.9 65.7 1.0 CA C:MET334 4.9 72.0 1.0

Fluorine binding site 10 out of 12 in the Ion Channel


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 10 of Ion Channel within 5.0Å range: probe atom residue distance (Å) B Occ B:F1301 b:20.0 occ:1.00 F01 B:LQ91301 0.0 20.0 1.0 C23 B:LQ91301 1.4 20.0 1.0 F02 B:LQ91301 2.2 20.0 1.0 F03 B:LQ91301 2.2 20.0 1.0 C19 B:LQ91301 2.4 20.0 1.0 SG B:CYS308 2.7 72.6 1.0 N09 B:LQ91301 2.9 20.0 1.0 CA B:GLY285 3.1 73.4 1.0 C B:GLY285 3.6 73.3 1.0 C18 B:LQ91301 3.7 20.0 1.0 CB B:CYS308 3.7 67.2 1.0 CG B:MET334 3.9 73.1 1.0 O B:GLY285 4.0 73.6 1.0 N08 B:LQ91301 4.2 20.0 1.0 N B:GLY285 4.2 72.9 1.0 N B:THR286 4.3 71.2 1.0 CA B:CYS308 4.4 65.0 1.0 C14 B:LQ91301 4.6 20.0 1.0 O B:LEU281 4.6 76.5 1.0 CB B:MET334 4.7 72.0 1.0 O B:CYS308 4.8 65.0 1.0 O B:VAL282 4.9 73.5 1.0 CE B:MET334 4.9 75.1 1.0 CG2 B:THR311 5.0 60.4 1.0

J.Zhang, S.Liu, J.Fan, R.Yan, B.Huang, F.Zhou, T.Yuan, J.Gong, Z.Huang, D.Jiang. Structural Basis of Human SLO2.2 Channel Gating and Modulation. Cell Rep V. 42 12858 2023.
ISSN: ESSN 2211-1247
PubMed: 37494189
DOI: 10.1016/J.CELREP.2023.112858