Fluorine in PDB 8ium: Cryo-Em Structure of the Tafluprost Acid-Bound Human Ptgfr-Gq Complex

The binding sites of Fluorine atom in the Cryo-Em Structure of the Tafluprost Acid-Bound Human Ptgfr-Gq Complex (pdb code 8ium). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Cryo-Em Structure of the Tafluprost Acid-Bound Human Ptgfr-Gq Complex, PDB code: 8ium:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in the Cryo-Em Structure of the Tafluprost Acid-Bound Human Ptgfr-Gq Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Cryo-Em Structure of the Tafluprost Acid-Bound Human Ptgfr-Gq Complex within 5.0Å range: probe atom residue distance (Å) B Occ R:F401 b:20.0 occ:1.00 F20 R:S2F401 0.0 20.0 1.0 C19 R:S2F401 1.4 20.0 1.0 F21 R:S2F401 2.3 20.0 1.0 C22 R:S2F401 2.4 20.0 1.0 C18 R:S2F401 2.4 20.0 1.0 O23 R:S2F401 2.6 20.0 1.0 CE1 R:HIS81 2.8 51.9 1.0 NE2 R:GLN297 2.9 54.1 1.0 ND1 R:HIS81 3.1 51.9 1.0 C17 R:S2F401 3.3 20.0 1.0 OG R:SER118 3.3 51.9 1.0 CD R:GLN297 3.7 54.1 1.0 C24 R:S2F401 3.9 20.0 1.0 NE2 R:HIS81 4.0 51.9 1.0 OE1 R:GLN297 4.1 54.1 1.0 OG1 R:THR294 4.1 55.7 1.0 C16 R:S2F401 4.5 20.0 1.0 CG R:HIS81 4.5 51.9 1.0 CB R:SER118 4.5 51.9 1.0 CB R:THR294 4.6 55.7 1.0 CA R:THR294 4.6 55.7 1.0 CB R:GLN297 4.7 54.1 1.0 CG R:GLN297 4.7 54.1 1.0 C25 R:S2F401 4.8 20.0 1.0 C29 R:S2F401 4.8 20.0 1.0 CD2 R:HIS81 4.9 51.9 1.0 ND2 R:ASN84 5.0 52.5 1.0

Fluorine binding site 2 out of 2 in the Cryo-Em Structure of the Tafluprost Acid-Bound Human Ptgfr-Gq Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Cryo-Em Structure of the Tafluprost Acid-Bound Human Ptgfr-Gq Complex within 5.0Å range: probe atom residue distance (Å) B Occ R:F401 b:20.0 occ:1.00 F21 R:S2F401 0.0 20.0 1.0 C19 R:S2F401 1.4 20.0 1.0 F20 R:S2F401 2.3 20.0 1.0 C18 R:S2F401 2.4 20.0 1.0 C22 R:S2F401 2.4 20.0 1.0 ND2 R:ASN84 2.8 52.5 1.0 C17 R:S2F401 2.9 20.0 1.0 O23 R:S2F401 3.2 20.0 1.0 OG R:SER118 3.3 51.9 1.0 CG R:ASN84 3.3 52.5 1.0 OD1 R:ASN84 3.8 52.5 1.0 ND1 R:HIS81 3.8 51.9 1.0 CB R:SER118 3.9 51.9 1.0 CB R:ASN84 4.0 52.5 1.0 O R:GLY80 4.2 51.0 1.0 CE1 R:HIS81 4.2 51.9 1.0 C16 R:S2F401 4.2 20.0 1.0 C24 R:S2F401 4.3 20.0 1.0 C R:GLY80 4.4 51.0 1.0 C25 R:S2F401 4.5 20.0 1.0 N R:HIS81 4.6 51.9 1.0 C08 R:S2F401 4.7 20.0 1.0 CA R:HIS81 4.8 51.9 1.0 C10 R:S2F401 4.8 20.0 1.0 CG R:MET115 4.8 52.1 1.0 O R:CYS114 4.8 50.8 1.0 NE2 R:GLN297 4.9 54.1 1.0

C.Wu, Y.Xu, Q.He, D.Li, J.Duan, C.Li, C.You, H.Chen, W.Fan, Y.Jiang, H.Eric Xu. Ligand-Induced Activation and G Protein Coupling of Prostaglandin F 2 Alpha Receptor. Nat Commun V. 14 2668 2023.
ISSN: ESSN 2041-1723
PubMed: 37160891
DOI: 10.1038/S41467-023-38411-X