Fluorine in PDB 8iys: TUG891-Bound FFAR4 in Complex with Gq

The binding sites of Fluorine atom in the TUG891-Bound FFAR4 in Complex with Gq (pdb code 8iys). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the TUG891-Bound FFAR4 in Complex with Gq, PDB code: 8iys:

Fluorine binding site 1 out of 1 in the TUG891-Bound FFAR4 in Complex with Gq


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of TUG891-Bound FFAR4 in Complex with Gq within 5.0Å range: probe atom residue distance (Å) B Occ R:F401 b:48.8 occ:1.00 F1 R:YN9401 0.0 48.8 1.0 C19 R:YN9401 1.4 48.8 1.0 C18 R:YN9401 2.4 48.8 1.0 C8 R:YN9401 2.4 48.8 1.0 SD R:MET118 2.9 42.9 1.0 CZ R:PHE28 3.0 59.2 1.0 CG1 R:VAL307 3.2 47.2 1.0 CG2 R:VAL307 3.3 47.2 1.0 CE2 R:PHE28 3.3 59.2 1.0 C7 R:YN9401 3.7 48.8 1.0 C2 R:YN9401 3.7 48.8 1.0 CB R:VAL307 3.9 47.2 1.0 CE R:MET118 4.0 42.9 1.0 CE1 R:PHE28 4.2 59.2 1.0 C1 R:YN9401 4.2 48.8 1.0 CZ R:PHE303 4.4 54.6 1.0 CE2 R:PHE303 4.4 54.6 1.0 CG R:MET118 4.5 42.9 1.0 CD2 R:PHE28 4.7 59.2 1.0 CB R:MET118 4.7 42.9 1.0 CE2 R:PHE311 4.9 45.8 1.0 CE2 R:PHE115 5.0 50.0 1.0 C4 R:YN9401 5.0 48.8 1.0

H.Yin, A.Inoue, Z.Ma, X.Zhu, R.Xia, Z.Xu, N.Wang, Y.Duan, A.Zhang, C.Guo, Y.He. Structural Basis of Omega-3 Fatty Acid Receptor FFAR4 Activation and G Protein Coupling Selectivity. Cell Res. 2023.
ISSN: ISSN 1001-0602
PubMed: 37286793
DOI: 10.1038/S41422-023-00835-X