Atomistry » Fluorine » PDB 8ijw-8oo9 » 8jpe
Atomistry »
  Fluorine »
    PDB 8ijw-8oo9 »
      8jpe »

Fluorine in PDB 8jpe: Focused Refinement Structure of Galpha(Q) in NTSR1-GRK2-Galpha(Q) Complexes

Other elements in 8jpe:

The structure of Focused Refinement Structure of Galpha(Q) in NTSR1-GRK2-Galpha(Q) Complexes also contains other interesting chemical elements:

Aluminium (Al) 1 atom
Magnesium (Mg) 1 atom

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Focused Refinement Structure of Galpha(Q) in NTSR1-GRK2-Galpha(Q) Complexes (pdb code 8jpe). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Focused Refinement Structure of Galpha(Q) in NTSR1-GRK2-Galpha(Q) Complexes, PDB code: 8jpe:
Jump to Fluorine binding site number: 1; 2; 3; 4;

Fluorine binding site 1 out of 4 in 8jpe

Go back to Fluorine Binding Sites List in 8jpe
Fluorine binding site 1 out of 4 in the Focused Refinement Structure of Galpha(Q) in NTSR1-GRK2-Galpha(Q) Complexes


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Focused Refinement Structure of Galpha(Q) in NTSR1-GRK2-Galpha(Q) Complexes within 5.0Å range:
probe atom residue distance (Å) B Occ
Q:F403

b:96.7
occ:1.00
 F1 Q:ALF403 0.0 96.7 1.0
AL Q:ALF403 1.8 96.7 1.0
O2A Q:GDP401 2.3 99.5 1.0
O2B Q:GDP401 2.3 99.5 1.0
F4 Q:ALF403 2.5 96.7 1.0
F3 Q:ALF403 2.5 96.7 1.0
NH2 Q:ARG183 3.2 103.4 1.0
PB Q:GDP401 3.3 99.5 1.0
O3B Q:GDP401 3.3 99.5 1.0
NH1 Q:ARG183 3.5 103.4 1.0
CZ Q:ARG183 3.5 103.4 1.0
PA Q:GDP401 3.6 99.5 1.0
F2 Q:ALF403 3.6 96.7 1.0
O3A Q:GDP401 3.9 99.5 1.0
MG Q:MG402 3.9 87.4 1.0
N Q:GLU49 3.9 101.9 1.0
CA Q:PRO185 4.1 95.8 1.0
CA Q:GLU49 4.2 101.9 1.0
N Q:THR186 4.3 89.8 1.0
NE Q:ARG183 4.5 103.4 1.0
O5' Q:GDP401 4.5 99.5 1.0
O1A Q:GDP401 4.6 99.5 1.0
O1B Q:GDP401 4.6 99.5 1.0
C5' Q:GDP401 4.6 99.5 1.0
O Q:VAL184 4.7 101.1 1.0
C Q:PRO185 4.8 95.8 1.0
N Q:PRO185 4.9 95.8 1.0
CB Q:PRO185 4.9 95.8 1.0
C Q:GLY48 5.0 92.4 1.0

Fluorine binding site 2 out of 4 in 8jpe

Go back to Fluorine Binding Sites List in 8jpe
Fluorine binding site 2 out of 4 in the Focused Refinement Structure of Galpha(Q) in NTSR1-GRK2-Galpha(Q) Complexes


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Focused Refinement Structure of Galpha(Q) in NTSR1-GRK2-Galpha(Q) Complexes within 5.0Å range:
probe atom residue distance (Å) B Occ
Q:F403

b:96.7
occ:1.00
 F2 Q:ALF403 0.0 96.7 1.0
AL Q:ALF403 1.8 96.7 1.0
N Q:GLY208 2.4 88.3 1.0
F3 Q:ALF403 2.5 96.7 1.0
F4 Q:ALF403 2.5 96.7 1.0
C Q:GLY207 3.3 80.2 1.0
CA Q:GLY207 3.3 80.2 1.0
CA Q:GLY208 3.3 88.3 1.0
O2B Q:GDP401 3.5 99.5 1.0
F1 Q:ALF403 3.6 96.7 1.0
N Q:GLN209 3.9 89.5 1.0
CA Q:GLY48 4.0 92.4 1.0
C Q:GLY208 4.0 88.3 1.0
O Q:THR186 4.1 89.8 1.0
NZ Q:LYS52 4.2 94.6 1.0
O3B Q:GDP401 4.3 99.5 1.0
O Q:VAL206 4.4 80.0 1.0
O Q:GLY207 4.4 80.2 1.0
PB Q:GDP401 4.4 99.5 1.0
CE Q:LYS52 4.5 94.6 1.0
N Q:GLY207 4.6 80.2 1.0
MG Q:MG402 4.6 87.4 1.0
N Q:GLU49 4.6 101.9 1.0
CG Q:GLN209 4.8 89.5 1.0
O1B Q:GDP401 4.8 99.5 1.0
N Q:THR186 4.8 89.8 1.0
N Q:GLY48 4.8 92.4 1.0
C Q:GLY48 4.9 92.4 1.0
C Q:THR186 4.9 89.8 1.0
C Q:VAL206 4.9 80.0 1.0

Fluorine binding site 3 out of 4 in 8jpe

Go back to Fluorine Binding Sites List in 8jpe
Fluorine binding site 3 out of 4 in the Focused Refinement Structure of Galpha(Q) in NTSR1-GRK2-Galpha(Q) Complexes


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Focused Refinement Structure of Galpha(Q) in NTSR1-GRK2-Galpha(Q) Complexes within 5.0Å range:
probe atom residue distance (Å) B Occ
Q:F403

b:96.7
occ:1.00
 F3 Q:ALF403 0.0 96.7 1.0
AL Q:ALF403 1.8 96.7 1.0
MG Q:MG402 2.3 87.4 1.0
F2 Q:ALF403 2.5 96.7 1.0
F1 Q:ALF403 2.5 96.7 1.0
O3B Q:GDP401 2.8 99.5 1.0
N Q:THR186 3.0 89.8 1.0
CB Q:THR186 3.2 89.8 1.0
O2B Q:GDP401 3.2 99.5 1.0
CA Q:THR186 3.5 89.8 1.0
PB Q:GDP401 3.6 99.5 1.0
F4 Q:ALF403 3.6 96.7 1.0
OG1 Q:THR186 3.6 89.8 1.0
O Q:THR186 3.7 89.8 1.0
C Q:THR186 4.0 89.8 1.0
O2A Q:GDP401 4.0 99.5 1.0
C Q:PRO185 4.0 95.8 1.0
CA Q:PRO185 4.2 95.8 1.0
OG Q:SER53 4.2 91.8 1.0
CA Q:GLY207 4.5 80.2 1.0
CG2 Q:THR186 4.5 89.8 1.0
O1B Q:GDP401 4.5 99.5 1.0
O Q:VAL184 4.6 101.1 1.0
N Q:GLY208 4.7 88.3 1.0
O Q:VAL206 4.8 80.0 1.0
O3A Q:GDP401 4.8 99.5 1.0
PA Q:GDP401 5.0 99.5 1.0

Fluorine binding site 4 out of 4 in 8jpe

Go back to Fluorine Binding Sites List in 8jpe
Fluorine binding site 4 out of 4 in the Focused Refinement Structure of Galpha(Q) in NTSR1-GRK2-Galpha(Q) Complexes


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Focused Refinement Structure of Galpha(Q) in NTSR1-GRK2-Galpha(Q) Complexes within 5.0Å range:
probe atom residue distance (Å) B Occ
Q:F403

b:96.7
occ:1.00
 F4 Q:ALF403 0.0 96.7 1.0
AL Q:ALF403 1.8 96.7 1.0
N Q:GLU49 2.5 101.9 1.0
F1 Q:ALF403 2.5 96.7 1.0
F2 Q:ALF403 2.5 96.7 1.0
O2B Q:GDP401 2.7 99.5 1.0
CA Q:GLY48 2.8 92.4 1.0
C Q:GLY48 3.0 92.4 1.0
NH2 Q:ARG183 3.5 103.4 1.0
CA Q:GLU49 3.6 101.9 1.0
F3 Q:ALF403 3.6 96.7 1.0
NE2 Q:GLN209 3.8 89.5 1.0
N Q:GLY48 4.1 92.4 1.0
PB Q:GDP401 4.2 99.5 1.0
O Q:GLY48 4.2 92.4 1.0
CG Q:GLU49 4.3 101.9 1.0
N Q:GLY208 4.3 88.3 1.0
CB Q:GLU49 4.4 101.9 1.0
O2A Q:GDP401 4.5 99.5 1.0
CA Q:GLY208 4.5 88.3 1.0
CZ Q:ARG183 4.6 103.4 1.0
C Q:GLU49 4.7 101.9 1.0
O3B Q:GDP401 4.7 99.5 1.0
N Q:GLN209 4.7 89.5 1.0
O Q:THR47 4.7 88.8 1.0
CD Q:GLN209 4.7 89.5 1.0
C Q:GLY208 4.8 88.3 1.0
NZ Q:LYS52 4.8 94.6 1.0
CG Q:GLN209 4.8 89.5 1.0
N Q:SER50 4.8 97.6 1.0
O1B Q:GDP401 4.9 99.5 1.0
C Q:THR47 4.9 88.8 1.0
NH1 Q:ARG183 4.9 103.4 1.0

Reference:

J.Duan, H.Liu, F.Zhao, Q.Yuan, Y.Ji, X.Cai, X.He, X.Li, J.Li, K.Wu, T.Gao, S.Zhu, S.Lin, M.W.Wang, X.Cheng, W.Yin, Y.Jiang, D.Yang, H.E.Xu. Gpcr Activation and GRK2 Assembly By A Biased Intracellular Agonist. Nature 2023.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-023-06395-9
Page generated: Thu Dec 28 04:38:11 2023

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy