Fluorine in PDB 8jwg: Cryo-Em Structure of Plasmodium Falciparum Multidrug Resistance Protein 1 Without H1 Helix in Complex with Mfq
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Cryo-Em Structure of Plasmodium Falciparum Multidrug Resistance Protein 1 Without H1 Helix in Complex with Mfq
(pdb code 8jwg). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 6 binding sites of Fluorine where determined in the
Cryo-Em Structure of Plasmodium Falciparum Multidrug Resistance Protein 1 Without H1 Helix in Complex with Mfq, PDB code: 8jwg:
Jump to Fluorine binding site number:
1;
2;
3;
4;
5;
6;
Fluorine binding site 1 out
of 6 in 8jwg
Go back to
Fluorine Binding Sites List in 8jwg
Fluorine binding site 1 out
of 6 in the Cryo-Em Structure of Plasmodium Falciparum Multidrug Resistance Protein 1 Without H1 Helix in Complex with Mfq
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Cryo-Em Structure of Plasmodium Falciparum Multidrug Resistance Protein 1 Without H1 Helix in Complex with Mfq within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F1500
b:79.5
occ:1.00
|
FAE
|
A:YMZ1500
|
0.0
|
79.5
|
1.0
|
CAZ
|
A:YMZ1500
|
1.4
|
79.5
|
1.0
|
FAF
|
A:YMZ1500
|
2.2
|
79.5
|
1.0
|
FAG
|
A:YMZ1500
|
2.2
|
79.5
|
1.0
|
CAT
|
A:YMZ1500
|
2.4
|
79.5
|
1.0
|
CAI
|
A:YMZ1500
|
2.7
|
79.5
|
1.0
|
CG
|
A:GLN1038
|
3.3
|
72.3
|
1.0
|
CAV
|
A:YMZ1500
|
3.7
|
79.5
|
1.0
|
CB
|
A:GLN1038
|
3.8
|
72.3
|
1.0
|
CAH
|
A:YMZ1500
|
4.1
|
79.5
|
1.0
|
NAP
|
A:YMZ1500
|
4.2
|
79.5
|
1.0
|
O
|
A:SER1034
|
4.3
|
81.8
|
1.0
|
N
|
A:GLN1038
|
4.5
|
72.3
|
1.0
|
O
|
A:GLN1035
|
4.5
|
78.4
|
1.0
|
CD
|
A:GLN1038
|
4.6
|
72.3
|
1.0
|
CA
|
A:GLN1038
|
4.8
|
72.3
|
1.0
|
CAU
|
A:YMZ1500
|
4.8
|
79.5
|
1.0
|
C
|
A:GLN1035
|
4.9
|
78.4
|
1.0
|
CAJ
|
A:YMZ1500
|
5.0
|
79.5
|
1.0
|
NE2
|
A:GLN1038
|
5.0
|
72.3
|
1.0
|
|
Fluorine binding site 2 out
of 6 in 8jwg
Go back to
Fluorine Binding Sites List in 8jwg
Fluorine binding site 2 out
of 6 in the Cryo-Em Structure of Plasmodium Falciparum Multidrug Resistance Protein 1 Without H1 Helix in Complex with Mfq
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Cryo-Em Structure of Plasmodium Falciparum Multidrug Resistance Protein 1 Without H1 Helix in Complex with Mfq within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F1500
b:79.5
occ:1.00
|
FAF
|
A:YMZ1500
|
0.0
|
79.5
|
1.0
|
CAZ
|
A:YMZ1500
|
1.4
|
79.5
|
1.0
|
FAG
|
A:YMZ1500
|
2.2
|
79.5
|
1.0
|
FAE
|
A:YMZ1500
|
2.2
|
79.5
|
1.0
|
CAT
|
A:YMZ1500
|
2.4
|
79.5
|
1.0
|
NAP
|
A:YMZ1500
|
2.9
|
79.5
|
1.0
|
CAV
|
A:YMZ1500
|
3.0
|
79.5
|
1.0
|
CAI
|
A:YMZ1500
|
3.4
|
79.5
|
1.0
|
CB
|
A:GLN1038
|
3.5
|
72.3
|
1.0
|
CG
|
A:GLN1038
|
3.6
|
72.3
|
1.0
|
CAR
|
A:YMZ1500
|
4.1
|
79.5
|
1.0
|
FAD
|
A:YMZ1500
|
4.2
|
79.5
|
1.0
|
CAU
|
A:YMZ1500
|
4.3
|
79.5
|
1.0
|
CAH
|
A:YMZ1500
|
4.6
|
79.5
|
1.0
|
CA
|
A:GLN1038
|
4.7
|
72.3
|
1.0
|
CAY
|
A:YMZ1500
|
4.8
|
79.5
|
1.0
|
N
|
A:GLN1038
|
4.8
|
72.3
|
1.0
|
CAJ
|
A:YMZ1500
|
4.9
|
79.5
|
1.0
|
O
|
A:GLN1035
|
5.0
|
78.4
|
1.0
|
|
Fluorine binding site 3 out
of 6 in 8jwg
Go back to
Fluorine Binding Sites List in 8jwg
Fluorine binding site 3 out
of 6 in the Cryo-Em Structure of Plasmodium Falciparum Multidrug Resistance Protein 1 Without H1 Helix in Complex with Mfq
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Cryo-Em Structure of Plasmodium Falciparum Multidrug Resistance Protein 1 Without H1 Helix in Complex with Mfq within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F1500
b:79.5
occ:1.00
|
FAG
|
A:YMZ1500
|
0.0
|
79.5
|
1.0
|
CAZ
|
A:YMZ1500
|
1.4
|
79.5
|
1.0
|
FAF
|
A:YMZ1500
|
2.2
|
79.5
|
1.0
|
FAE
|
A:YMZ1500
|
2.2
|
79.5
|
1.0
|
CAT
|
A:YMZ1500
|
2.4
|
79.5
|
1.0
|
NAP
|
A:YMZ1500
|
2.9
|
79.5
|
1.0
|
CAV
|
A:YMZ1500
|
3.0
|
79.5
|
1.0
|
CAI
|
A:YMZ1500
|
3.4
|
79.5
|
1.0
|
CAR
|
A:YMZ1500
|
4.1
|
79.5
|
1.0
|
FAD
|
A:YMZ1500
|
4.2
|
79.5
|
1.0
|
CAU
|
A:YMZ1500
|
4.3
|
79.5
|
1.0
|
O
|
A:GLN1035
|
4.5
|
78.4
|
1.0
|
CAH
|
A:YMZ1500
|
4.6
|
79.5
|
1.0
|
CAY
|
A:YMZ1500
|
4.8
|
79.5
|
1.0
|
CAJ
|
A:YMZ1500
|
4.9
|
79.5
|
1.0
|
|
Fluorine binding site 4 out
of 6 in 8jwg
Go back to
Fluorine Binding Sites List in 8jwg
Fluorine binding site 4 out
of 6 in the Cryo-Em Structure of Plasmodium Falciparum Multidrug Resistance Protein 1 Without H1 Helix in Complex with Mfq
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Cryo-Em Structure of Plasmodium Falciparum Multidrug Resistance Protein 1 Without H1 Helix in Complex with Mfq within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F1500
b:79.5
occ:1.00
|
FAC
|
A:YMZ1500
|
0.0
|
79.5
|
1.0
|
CAY
|
A:YMZ1500
|
1.4
|
79.5
|
1.0
|
FAB
|
A:YMZ1500
|
2.2
|
79.5
|
1.0
|
FAD
|
A:YMZ1500
|
2.2
|
79.5
|
1.0
|
CAR
|
A:YMZ1500
|
2.4
|
79.5
|
1.0
|
CAK
|
A:YMZ1500
|
3.0
|
79.5
|
1.0
|
NAP
|
A:YMZ1500
|
3.4
|
79.5
|
1.0
|
CG2
|
A:ILE328
|
3.9
|
69.9
|
1.0
|
CE
|
A:MET332
|
4.0
|
71.3
|
1.0
|
CD1
|
A:LEU71
|
4.2
|
64.8
|
1.0
|
CAS
|
A:YMZ1500
|
4.2
|
79.5
|
1.0
|
CAV
|
A:YMZ1500
|
4.6
|
79.5
|
1.0
|
CD1
|
A:ILE328
|
4.9
|
69.9
|
1.0
|
CAU
|
A:YMZ1500
|
4.9
|
79.5
|
1.0
|
|
Fluorine binding site 5 out
of 6 in 8jwg
Go back to
Fluorine Binding Sites List in 8jwg
Fluorine binding site 5 out
of 6 in the Cryo-Em Structure of Plasmodium Falciparum Multidrug Resistance Protein 1 Without H1 Helix in Complex with Mfq
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 5 of Cryo-Em Structure of Plasmodium Falciparum Multidrug Resistance Protein 1 Without H1 Helix in Complex with Mfq within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F1500
b:79.5
occ:1.00
|
FAD
|
A:YMZ1500
|
0.0
|
79.5
|
1.0
|
CAY
|
A:YMZ1500
|
1.4
|
79.5
|
1.0
|
FAB
|
A:YMZ1500
|
2.2
|
79.5
|
1.0
|
FAC
|
A:YMZ1500
|
2.2
|
79.5
|
1.0
|
CAR
|
A:YMZ1500
|
2.4
|
79.5
|
1.0
|
NAP
|
A:YMZ1500
|
2.7
|
79.5
|
1.0
|
CAK
|
A:YMZ1500
|
3.7
|
79.5
|
1.0
|
CD1
|
A:LEU71
|
3.7
|
64.8
|
1.0
|
CD2
|
A:LEU71
|
3.8
|
64.8
|
1.0
|
CAV
|
A:YMZ1500
|
4.1
|
79.5
|
1.0
|
FAF
|
A:YMZ1500
|
4.2
|
79.5
|
1.0
|
FAG
|
A:YMZ1500
|
4.2
|
79.5
|
1.0
|
CG
|
A:LEU71
|
4.3
|
64.8
|
1.0
|
CAZ
|
A:YMZ1500
|
4.7
|
79.5
|
1.0
|
CAS
|
A:YMZ1500
|
4.8
|
79.5
|
1.0
|
CAT
|
A:YMZ1500
|
4.9
|
79.5
|
1.0
|
CAU
|
A:YMZ1500
|
4.9
|
79.5
|
1.0
|
|
Fluorine binding site 6 out
of 6 in 8jwg
Go back to
Fluorine Binding Sites List in 8jwg
Fluorine binding site 6 out
of 6 in the Cryo-Em Structure of Plasmodium Falciparum Multidrug Resistance Protein 1 Without H1 Helix in Complex with Mfq
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 6 of Cryo-Em Structure of Plasmodium Falciparum Multidrug Resistance Protein 1 Without H1 Helix in Complex with Mfq within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F1500
b:79.5
occ:1.00
|
FAB
|
A:YMZ1500
|
0.0
|
79.5
|
1.0
|
CAY
|
A:YMZ1500
|
1.4
|
79.5
|
1.0
|
FAC
|
A:YMZ1500
|
2.2
|
79.5
|
1.0
|
FAD
|
A:YMZ1500
|
2.2
|
79.5
|
1.0
|
CAR
|
A:YMZ1500
|
2.4
|
79.5
|
1.0
|
CAK
|
A:YMZ1500
|
2.9
|
79.5
|
1.0
|
NAP
|
A:YMZ1500
|
3.4
|
79.5
|
1.0
|
CD1
|
A:ILE328
|
3.9
|
69.9
|
1.0
|
CAS
|
A:YMZ1500
|
4.2
|
79.5
|
1.0
|
CG2
|
A:ILE328
|
4.4
|
69.9
|
1.0
|
CD1
|
A:LEU71
|
4.5
|
64.8
|
1.0
|
CD2
|
A:LEU71
|
4.6
|
64.8
|
1.0
|
CAV
|
A:YMZ1500
|
4.6
|
79.5
|
1.0
|
CG1
|
A:ILE328
|
4.7
|
69.9
|
1.0
|
CAU
|
A:YMZ1500
|
4.9
|
79.5
|
1.0
|
|
Reference:
K.Si,
X.He,
L.Chen,
A.Zhang,
C.Guo,
M.Li.
The Structure of Plasmodium Falciparum Multidrug Resistance Protein 1 Reveals An N-Terminal Regulatory Domain. Proc.Natl.Acad.Sci.Usa V. 120 05120 2023.
ISSN: ESSN 1091-6490
PubMed: 37527341
DOI: 10.1073/PNAS.2219905120
Page generated: Fri Aug 2 21:03:55 2024
|