Fluorine in PDB 8k2w: Structure of CXCR3 Complexed with Antagonist AMG487

The binding sites of Fluorine atom in the Structure of CXCR3 Complexed with Antagonist AMG487 (pdb code 8k2w). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Structure of CXCR3 Complexed with Antagonist AMG487, PDB code: 8k2w:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in the Structure of CXCR3 Complexed with Antagonist AMG487


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of CXCR3 Complexed with Antagonist AMG487 within 5.0Å range: probe atom residue distance (Å) B Occ R:F404 b:56.5 occ:1.00 F1 R:FI6404 0.0 56.5 1.0 C32 R:FI6404 1.3 55.6 1.0 F2 R:FI6404 2.1 59.0 1.0 F3 R:FI6404 2.1 50.7 1.0 O4 R:FI6404 2.2 46.6 1.0 C29 R:FI6404 2.8 41.0 1.0 C28 R:FI6404 2.8 40.0 1.0 CD2 R:LEU56 4.0 44.1 1.0 C30 R:FI6404 4.1 38.4 1.0 C27 R:FI6404 4.1 37.0 1.0 CD1 R:LEU56 4.3 42.9 1.0 CG R:LEU56 4.5 39.3 1.0

Fluorine binding site 2 out of 3 in the Structure of CXCR3 Complexed with Antagonist AMG487


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Structure of CXCR3 Complexed with Antagonist AMG487 within 5.0Å range: probe atom residue distance (Å) B Occ R:F404 b:59.0 occ:1.00 F2 R:FI6404 0.0 59.0 1.0 C32 R:FI6404 1.3 55.6 1.0 F3 R:FI6404 2.1 50.7 1.0 F1 R:FI6404 2.1 56.5 1.0 O4 R:FI6404 2.2 46.6 1.0 C29 R:FI6404 3.5 41.0 1.0 C28 R:FI6404 4.1 40.0 1.0 C30 R:FI6404 4.6 38.4 1.0 CG2 R:VAL310 4.8 26.8 1.0

Fluorine binding site 3 out of 3 in the Structure of CXCR3 Complexed with Antagonist AMG487


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Structure of CXCR3 Complexed with Antagonist AMG487 within 5.0Å range: probe atom residue distance (Å) B Occ R:F404 b:50.7 occ:1.00 F3 R:FI6404 0.0 50.7 1.0 C32 R:FI6404 1.3 55.6 1.0 F2 R:FI6404 2.1 59.0 1.0 F1 R:FI6404 2.1 56.5 1.0 O4 R:FI6404 2.2 46.6 1.0 C29 R:FI6404 2.8 41.0 1.0 C28 R:FI6404 2.9 40.0 1.0 C30 R:FI6404 4.1 38.4 1.0 C27 R:FI6404 4.1 37.0 1.0 CB R:SER309 4.3 36.7 1.0 CG2 R:VAL306 4.5 57.0 1.0 CG2 R:VAL310 4.6 26.8 1.0 OG R:SER309 4.9 41.9 1.0

H.Jiao, B.Pang, Y.Chiang, Q.Chen, Q.Pan, R.Ren, H.Hu. Structure Basis For the Modulation of Cxc Chemokine Receptor 3 By Antagonist AMG487 Cell Discov 2023.
ISSN: ESSN 2056-5968