|
Fluorine in PDB 8ous: Crystal Structure of Dlk in Complex with Compound 19Enzymatic activity of Crystal Structure of Dlk in Complex with Compound 19
All present enzymatic activity of Crystal Structure of Dlk in Complex with Compound 19:
2.7.11.25; Protein crystallography data
The structure of Crystal Structure of Dlk in Complex with Compound 19, PDB code: 8ous
was solved by
M.Zebisch,
P.A.Mcewan,
J.J.Barker,
J.B.Cross,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Dlk in Complex with Compound 19
(pdb code 8ous). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structure of Dlk in Complex with Compound 19, PDB code: 8ous: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 8ousGo back to Fluorine Binding Sites List in 8ous
Fluorine binding site 1 out
of 3 in the Crystal Structure of Dlk in Complex with Compound 19
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 8ousGo back to Fluorine Binding Sites List in 8ous
Fluorine binding site 2 out
of 3 in the Crystal Structure of Dlk in Complex with Compound 19
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 8ousGo back to Fluorine Binding Sites List in 8ous
Fluorine binding site 3 out
of 3 in the Crystal Structure of Dlk in Complex with Compound 19
Mono view Stereo pair view
Reference:
K.Le,
M.J.Soth,
J.B.Cross,
G.Liu,
W.J.Ray,
J.Ma,
S.G.Goodwani,
P.J.Acton,
V.Buggia-Prevot,
O.Akkermans,
J.Barker,
M.L.Conner,
Y.Jiang,
Z.Liu,
P.Mcewan,
J.Warner-Schmidt,
A.Xu,
M.Zebisch,
C.J.Heijnen,
B.Abrahams,
P.Jones.
Discovery of Iacs-52825, A Potent and Selective Dlk Inhibitor For Treatment of Chemotherapy-Induced Peripheral Neuropathy. J.Med.Chem. 2023.
Page generated: Fri Aug 2 21:15:32 2024
ISSN: ISSN 0022-2623 PubMed: 37436942 DOI: 10.1021/ACS.JMEDCHEM.3C00788 |
Last articlesZn in 9JPJZn in 9JP7 Zn in 9JPK Zn in 9JPL Zn in 9GN6 Zn in 9GN7 Zn in 9GKU Zn in 9GKW Zn in 9GKX Zn in 9GL0 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |