Fluorine in PDB 8oz2: Human Aldose Reductase Mutant A299G/L300A in Complex with A Ligand with An Idd Structure ({5-Fluoro-2-[(3-Nitrobenzyl) Carbamoyl]Phenoxy}Acetic Acid)

Enzymatic activity of Human Aldose Reductase Mutant A299G/L300A in Complex with A Ligand with An Idd Structure ({5-Fluoro-2-[(3-Nitrobenzyl) Carbamoyl]Phenoxy}Acetic Acid)

Protein crystallography data

Fluorine Binding Sites:

Fluorine binding site 1 out of 1 in 8oz2

Fluorine Binding Sites List in 8oz2

Fluorine binding site 1 out of 1 in the Human Aldose Reductase Mutant A299G/L300A in Complex with A Ligand with An Idd Structure ({5-Fluoro-2-[(3-Nitrobenzyl) Carbamoyl]Phenoxy}Acetic Acid)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Human Aldose Reductase Mutant A299G/L300A in Complex with A Ligand with An Idd Structure ({5-Fluoro-2-[(3-Nitrobenzyl) Carbamoyl]Phenoxy}Acetic Acid) within 5.0Å range: probe atom residue distance (Å) B Occ A:F402 b:9.2 occ:1.00 F27 A:30L402 0.0 9.2 1.0 C26 A:30L402 1.4 8.3 1.0 C24 A:30L402 2.3 9.1 1.0 C28 A:30L402 2.3 7.5 1.0 HD1 A:TYR48 2.7 6.5 1.0 HG13 A:VAL47 2.7 7.3 1.0 HA A:TYR48 3.1 6.7 1.0 O A:VAL47 3.2 6.2 1.0 HE1 A:TRP20 3.3 8.0 1.0 HG22 A:VAL47 3.3 7.4 1.0 O A:HOH910 3.4 10.4 1.0 O A:HOH710 3.5 14.2 1.0 HD1 A:TRP20 3.5 7.7 1.0 CD1 A:TYR48 3.6 5.5 1.0 C22 A:30L402 3.6 9.0 1.0 C30 A:30L402 3.6 7.1 1.0 NE1 A:TRP20 3.6 6.7 1.0 CG1 A:VAL47 3.7 6.1 1.0 O A:HOH569 3.7 7.5 1.0 C A:VAL47 3.7 5.5 1.0 CD1 A:TRP20 3.8 6.4 1.0 HE1 A:TYR48 3.9 6.5 1.0 CA A:TYR48 4.0 5.6 1.0 HG11 A:VAL47 4.1 7.3 1.0 N A:TYR48 4.1 5.2 1.0 CG2 A:VAL47 4.1 6.2 1.0 C21 A:30L402 4.1 8.0 1.0 CE1 A:TYR48 4.2 5.4 1.0 HG12 A:VAL47 4.2 7.3 1.0 HG21 A:VAL47 4.3 7.4 1.0 CB A:VAL47 4.3 5.9 1.0 CE2 A:TRP20 4.6 6.7 1.0 CG A:TYR48 4.6 5.5 1.0 CA A:VAL47 4.6 5.8 1.0 H A:TYR48 4.7 6.2 1.0 O31 A:30L402 4.8 6.5 1.0 O A:HOH964 4.8 8.6 1.0 CB A:TYR48 4.8 5.4 1.0 O A:HOH651 4.8 9.2 1.0 CG A:TRP20 4.8 6.3 1.0 HG23 A:VAL47 4.9 7.4 1.0 C A:TYR48 5.0 5.6 1.0

Reference: