Fluorine in PDB 8r8p: Solution Structure of Smn-Cx Bound to the Rna Helix Formed Upon SMN2 EXON7 5'-Splice Site Recognition

The binding sites of Fluorine atom in the Solution Structure of Smn-Cx Bound to the Rna Helix Formed Upon SMN2 EXON7 5'-Splice Site Recognition (pdb code 8r8p). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Solution Structure of Smn-Cx Bound to the Rna Helix Formed Upon SMN2 EXON7 5'-Splice Site Recognition, PDB code: 8r8p:

Fluorine binding site 1 out of 1 in the Solution Structure of Smn-Cx Bound to the Rna Helix Formed Upon SMN2 EXON7 5'-Splice Site Recognition


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Solution Structure of Smn-Cx Bound to the Rna Helix Formed Upon SMN2 EXON7 5'-Splice Site Recognition within 5.0Å range: probe atom residue distance (Å) B Occ B:F101 b:0.0 occ:1.00 F4 B:YB3101 0.0 0.0 1.0 C3 B:YB3101 1.3 0.0 1.0 C5 B:YB3101 2.3 0.0 1.0 C2 B:YB3101 2.3 0.0 1.0 H2 B:YB3101 2.6 0.0 1.0 N11 B:YB3101 2.9 0.0 1.0 N6 B:YB3101 3.6 0.0 1.0 OP2 B:G13 3.6 0.0 1.0 C1 B:YB3101 3.6 0.0 1.0 N7 B:G13 3.8 0.0 1.0 H8 B:G13 3.9 0.0 1.0 C8 B:G13 4.0 0.0 1.0 C9 B:YB3101 4.2 0.0 1.0 C7 B:YB3101 4.2 0.0 1.0 H18 B:YB3101 4.4 0.0 1.0 H3' B:G13 4.4 0.0 1.0 C8 B:YB3101 4.5 0.0 1.0 O5' B:G13 4.7 0.0 1.0 P B:G13 4.7 0.0 1.0 C5 B:G13 4.7 0.0 1.0 OP2 B:A14 4.8 0.0 1.0 C19 B:YB3101 4.8 0.0 1.0 H3' B:G12 4.9 0.0 1.0

F.Malard, A.Wolter, J.Marquevielle, E.Morvan, A.Ecoutin, S.Rudisser, F.H.Allain, S.Campagne. The Diversity of Splicing Modifiers Acting on A-1 Bulged 5'-Splice Sites Reveals Rules For Rational Drug Design To Be Published.