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Atomistry » Fluorine » PDB 8qow-8str » 8skl » |
Fluorine in PDB 8skl: PTP1B in Complex with 182Enzymatic activity of PTP1B in Complex with 182
All present enzymatic activity of PTP1B in Complex with 182:
3.1.3.48; Protein crystallography data
The structure of PTP1B in Complex with 182, PDB code: 8skl
was solved by
J.J.Babon,
H.Chen,
T.Tiganis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8skl:
The structure of PTP1B in Complex with 182 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the PTP1B in Complex with 182
(pdb code 8skl). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the PTP1B in Complex with 182, PDB code: 8skl: Fluorine binding site 1 out of 1 in 8sklGo back to Fluorine Binding Sites List in 8skl
Fluorine binding site 1 out
of 1 in the PTP1B in Complex with 182
Mono view Stereo pair view
Reference:
S.Liang,
E.Tran,
X.Du,
J.Dong,
H.Sudholz,
H.Chen,
Z.Qu,
N.Huntington,
J.Babon,
N.Kershaw,
Z.Y.Zhang,
J.Baell,
F.Wiede,
T.Tiganis.
A Small Molecule Inhibitor of PTP1B and PTPN2 Enhances T Cell Anti-Tumor Immunity. Biorxiv 2023.
Page generated: Thu Dec 28 04:48:25 2023
ISSN: ISSN 2692-8205 PubMed: 37397992 DOI: 10.1101/2023.06.16.545220 |
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