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Fluorine in PDB 8tlc: Human Mitochondrial Serine Hydroxymethyltransferase (SHMT2) in Complex with Plp, Glycine and Tri-Glutamate AGF347 InhibitorProtein crystallography data
The structure of Human Mitochondrial Serine Hydroxymethyltransferase (SHMT2) in Complex with Plp, Glycine and Tri-Glutamate AGF347 Inhibitor, PDB code: 8tlc
was solved by
J.M.Katinas,
C.E.Dann Iii,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Human Mitochondrial Serine Hydroxymethyltransferase (SHMT2) in Complex with Plp, Glycine and Tri-Glutamate AGF347 Inhibitor
(pdb code 8tlc). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Human Mitochondrial Serine Hydroxymethyltransferase (SHMT2) in Complex with Plp, Glycine and Tri-Glutamate AGF347 Inhibitor, PDB code: 8tlc: Fluorine binding site 1 out of 1 in 8tlcGo back to Fluorine Binding Sites List in 8tlc
Fluorine binding site 1 out
of 1 in the Human Mitochondrial Serine Hydroxymethyltransferase (SHMT2) in Complex with Plp, Glycine and Tri-Glutamate AGF347 Inhibitor
Mono view Stereo pair view
Reference:
J.M.Katinas,
M.J.Nayeen,
M.Schneider,
K.Shah,
A.N.Fifer,
L.M.Klapper,
A.Sharma,
K.Thalluri,
M.S.Van Nieuwenhze,
Z.Hou,
A.Gangjee,
L.H.Matherly,
C.E.Dann 3Rd.
Structural Characterization of 5-Substituted Pyrrolo[3,2- D ]Pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2. Biochemistry 2024.
Page generated: Sat Aug 3 00:29:47 2024
ISSN: ISSN 0006-2960 PubMed: 38324671 DOI: 10.1021/ACS.BIOCHEM.3C00613 |
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