Fluorine in PDB 8u9q: CDC48-SHP1 Unfolding Native Substrate, Class 6

All present enzymatic activity of CDC48-SHP1 Unfolding Native Substrate, Class 6:
3.6.4.6;

The structure of CDC48-SHP1 Unfolding Native Substrate, Class 6 also contains other interesting chemical elements:

Magnesium

(Mg)

6 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 18;

Binding sites:

The binding sites of Fluorine atom in the CDC48-SHP1 Unfolding Native Substrate, Class 6 (pdb code 8u9q). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 18 binding sites of Fluorine where determined in the CDC48-SHP1 Unfolding Native Substrate, Class 6, PDB code: 8u9q:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Fluorine binding site 1 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 6


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of CDC48-SHP1 Unfolding Native Substrate, Class 6 within 5.0Å range: probe atom residue distance (Å) B Occ A:F901 b:196.0 occ:1.00 F1 A:08T901 0.0 196.0 1.0 BE A:08T901 1.5 196.0 1.0 F3 A:08T901 2.5 196.0 1.0 F2 A:08T901 2.5 196.0 1.0 O3B A:08T901 2.6 197.3 1.0 O2B A:08T901 2.9 197.3 1.0 PB A:08T901 3.2 197.3 1.0 CE A:LYS261 3.5 189.3 1.0 OD2 B:ASP343 3.7 214.4 1.0 O1B A:08T901 3.9 197.3 1.0 NZ A:LYS261 4.1 189.3 1.0 CG A:LYS261 4.2 189.3 1.0 OG1 A:THR262 4.2 183.6 1.0 NH1 B:ARG369 4.3 210.1 1.0 CD A:LYS261 4.3 189.3 1.0 MG A:MG902 4.3 185.6 1.0 N A:GLY258 4.4 191.9 1.0 O3A A:08T901 4.6 197.3 1.0 NH2 B:ARG372 4.7 216.7 1.0 NH1 B:ARG372 4.9 216.7 1.0 CA A:PRO257 4.9 204.4 1.0 CG B:ASP343 4.9 214.4 1.0

Fluorine binding site 2 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 6


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of CDC48-SHP1 Unfolding Native Substrate, Class 6 within 5.0Å range: probe atom residue distance (Å) B Occ A:F901 b:196.0 occ:1.00 F2 A:08T901 0.0 196.0 1.0 BE A:08T901 1.6 196.0 1.0 NZ A:LYS261 2.5 189.3 1.0 F3 A:08T901 2.5 196.0 1.0 F1 A:08T901 2.5 196.0 1.0 O3B A:08T901 2.6 197.3 1.0 N A:GLY258 2.6 191.9 1.0 O1B A:08T901 2.9 197.3 1.0 CA A:PRO257 3.0 204.4 1.0 CE A:LYS261 3.0 189.3 1.0 O A:PRO256 3.1 201.9 1.0 C A:PRO257 3.1 204.4 1.0 PB A:08T901 3.2 197.3 1.0 N A:THR259 3.6 193.2 1.0 CA A:GLY258 3.7 191.9 1.0 CG A:LYS261 3.8 189.3 1.0 C A:PRO256 3.8 201.9 1.0 N A:PRO257 3.8 204.4 1.0 O2B A:08T901 3.9 197.3 1.0 CD A:LYS261 4.0 189.3 1.0 C A:GLY258 4.1 191.9 1.0 CB A:PRO257 4.1 204.4 1.0 O A:PRO257 4.2 204.4 1.0 NH1 B:ARG369 4.3 210.1 1.0 OD1 A:ASN358 4.4 229.3 1.0 OG1 A:THR259 4.4 193.2 1.0 O3A A:08T901 4.6 197.3 1.0 CA A:THR259 4.7 193.2 1.0 CB A:THR259 4.7 193.2 1.0 O A:GLY255 4.8 211.9 1.0 N A:GLY260 4.9 184.3 1.0 CG A:ASN358 4.9 229.3 1.0

Fluorine binding site 3 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 6


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of CDC48-SHP1 Unfolding Native Substrate, Class 6 within 5.0Å range: probe atom residue distance (Å) B Occ A:F901 b:196.0 occ:1.00 F3 A:08T901 0.0 196.0 1.0 BE A:08T901 1.5 196.0 1.0 NH1 B:ARG369 2.5 210.1 1.0 F2 A:08T901 2.5 196.0 1.0 F1 A:08T901 2.5 196.0 1.0 O3B A:08T901 2.6 197.3 1.0 N A:GLY258 2.8 191.9 1.0 CA A:PRO257 3.1 204.4 1.0 CB A:PRO257 3.3 204.4 1.0 C A:PRO257 3.4 204.4 1.0 NH1 B:ARG372 3.5 216.7 1.0 CZ B:ARG369 3.8 210.1 1.0 CA A:GLY258 3.8 191.9 1.0 PB A:08T901 4.0 197.3 1.0 OD2 B:ASP343 4.5 214.4 1.0 N A:PRO257 4.5 204.4 1.0 CZ B:ARG372 4.5 216.7 1.0 NH2 B:ARG372 4.5 216.7 1.0 O1B A:08T901 4.6 197.3 1.0 O2B A:08T901 4.6 197.3 1.0 CD B:ARG369 4.6 210.1 1.0 NH2 B:ARG369 4.6 210.1 1.0 NE B:ARG369 4.6 210.1 1.0 O A:PRO257 4.6 204.4 1.0 CB B:ALA366 4.8 205.7 1.0 ND2 A:ASN358 4.8 229.3 1.0 NZ A:LYS261 4.8 189.3 1.0 CG A:PRO257 4.8 204.4 1.0 O A:PRO256 4.9 201.9 1.0 CE A:LYS261 5.0 189.3 1.0 C A:GLY258 5.0 191.9 1.0

Fluorine binding site 4 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 6


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of CDC48-SHP1 Unfolding Native Substrate, Class 6 within 5.0Å range: probe atom residue distance (Å) B Occ A:F903 b:196.0 occ:1.00 F1 A:08T903 0.0 196.0 1.0 BE A:08T903 1.5 196.0 1.0 MG A:MG904 1.9 181.9 1.0 O1A A:08T903 2.4 192.4 1.0 F3 A:08T903 2.5 196.0 1.0 F2 A:08T903 2.5 196.0 1.0 OD2 B:ASP619 2.6 230.4 1.0 O3B A:08T903 2.6 192.4 1.0 O2B A:08T903 2.8 192.4 1.0 CG B:ASP619 2.9 230.4 1.0 PB A:08T903 3.0 192.4 1.0 OG1 A:THR535 3.1 183.3 1.0 OD1 B:ASP619 3.2 230.4 1.0 O3A A:08T903 3.3 192.4 1.0 PA A:08T903 3.5 192.4 1.0 CB A:THR535 3.9 183.3 1.0 CB B:ASP619 3.9 230.4 1.0 NH2 B:ARG648 4.0 222.4 1.0 O B:ASP619 4.2 230.4 1.0 O2A A:08T903 4.3 192.4 1.0 O1B A:08T903 4.5 192.4 1.0 NH2 B:ARG645 4.6 213.3 1.0 N A:THR535 4.6 183.3 1.0 C B:ASP619 4.6 230.4 1.0 O5' A:08T903 4.6 192.4 1.0 CZ B:ARG648 4.8 222.4 1.0 CG2 A:THR535 4.9 183.3 1.0 CA B:ASP619 4.9 230.4 1.0 CA A:THR535 4.9 183.3 1.0 NH1 B:ARG648 5.0 222.4 1.0

Fluorine binding site 5 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 6


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of CDC48-SHP1 Unfolding Native Substrate, Class 6 within 5.0Å range: probe atom residue distance (Å) B Occ A:F903 b:196.0 occ:1.00 F2 A:08T903 0.0 196.0 1.0 BE A:08T903 1.6 196.0 1.0 F3 A:08T903 2.5 196.0 1.0 F1 A:08T903 2.5 196.0 1.0 O3B A:08T903 2.6 192.4 1.0 O2B A:08T903 3.5 192.4 1.0 NH2 B:ARG648 3.5 222.4 1.0 PB A:08T903 3.6 192.4 1.0 MG A:MG904 3.6 181.9 1.0 CB A:PRO530 3.8 188.5 1.0 CA A:PRO530 4.0 188.5 1.0 OE2 A:GLU588 4.1 253.3 1.0 NH1 B:ARG648 4.2 222.4 1.0 OD2 B:ASP619 4.2 230.4 1.0 CZ B:ARG648 4.3 222.4 1.0 O1B A:08T903 4.6 192.4 1.0 NZ A:LYS534 4.6 185.7 1.0 CE A:LYS534 4.7 185.7 1.0 N A:GLY531 4.7 186.9 1.0 O3A A:08T903 4.7 192.4 1.0 OG1 A:THR535 4.8 183.3 1.0 O1A A:08T903 4.8 192.4 1.0 CG B:ASP619 4.8 230.4 1.0 C A:PRO530 5.0 188.5 1.0

Fluorine binding site 6 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 6


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of CDC48-SHP1 Unfolding Native Substrate, Class 6 within 5.0Å range: probe atom residue distance (Å) B Occ A:F903 b:196.0 occ:1.00 F3 A:08T903 0.0 196.0 1.0 BE A:08T903 1.5 196.0 1.0 OD2 B:ASP619 2.3 230.4 1.0 F2 A:08T903 2.5 196.0 1.0 F1 A:08T903 2.5 196.0 1.0 O3B A:08T903 2.6 192.4 1.0 NH1 B:ARG648 2.7 222.4 1.0 NH2 B:ARG645 2.8 213.3 1.0 NH2 B:ARG648 2.9 222.4 1.0 CZ B:ARG645 3.0 213.3 1.0 CZ B:ARG648 3.1 222.4 1.0 CG B:ASP619 3.2 230.4 1.0 NE B:ARG645 3.2 213.3 1.0 CB B:ASP619 3.6 230.4 1.0 CB A:PRO530 3.7 188.5 1.0 NH1 B:ARG645 3.8 213.3 1.0 N A:GLY531 3.9 186.9 1.0 PB A:08T903 4.0 192.4 1.0 O1A A:08T903 4.0 192.4 1.0 NE B:ARG648 4.2 222.4 1.0 OD1 B:ASP619 4.2 230.4 1.0 CD B:ARG645 4.2 213.3 1.0 CA A:PRO530 4.3 188.5 1.0 MG A:MG904 4.3 181.9 1.0 O3A A:08T903 4.4 192.4 1.0 O2B A:08T903 4.5 192.4 1.0 C A:PRO530 4.6 188.5 1.0 CA A:GLY531 4.9 186.9 1.0 PA A:08T903 4.9 192.4 1.0

Fluorine binding site 7 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 6


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of CDC48-SHP1 Unfolding Native Substrate, Class 6 within 5.0Å range: probe atom residue distance (Å) B Occ B:F901 b:210.2 occ:1.00 F1 B:08T901 0.0 210.2 1.0 BE B:08T901 1.5 210.2 1.0 MG B:MG902 2.2 201.3 1.0 F3 B:08T901 2.5 210.2 1.0 F2 B:08T901 2.6 210.2 1.0 O3B B:08T901 2.6 201.6 1.0 O2B B:08T901 2.7 201.6 1.0 PB B:08T901 3.1 201.6 1.0 OG1 B:THR262 3.4 192.1 1.0 NH2 C:ARG372 3.4 232.6 1.0 NH2 C:ARG369 3.7 236.2 1.0 CG B:LYS261 4.2 192.5 1.0 O3A B:08T901 4.2 201.6 1.0 O1B B:08T901 4.3 201.6 1.0 CD B:LYS261 4.4 192.5 1.0 CB B:THR262 4.5 192.1 1.0 CZ C:ARG372 4.6 232.6 1.0 CZ C:ARG369 4.7 236.2 1.0 NZ B:LYS261 4.8 192.5 1.0 N B:GLY258 4.9 204.5 1.0 NH1 C:ARG372 4.9 232.6 1.0 N B:THR262 5.0 192.1 1.0 NE C:ARG369 5.0 236.2 1.0

Fluorine binding site 8 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 6


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of CDC48-SHP1 Unfolding Native Substrate, Class 6 within 5.0Å range: probe atom residue distance (Å) B Occ B:F901 b:210.2 occ:1.00 F2 B:08T901 0.0 210.2 1.0 BE B:08T901 1.6 210.2 1.0 F3 B:08T901 2.5 210.2 1.0 F1 B:08T901 2.6 210.2 1.0 O3B B:08T901 2.6 201.6 1.0 NZ B:LYS261 2.7 192.5 1.0 CA B:PRO257 3.2 202.8 1.0 OD1 B:ASN358 3.2 225.8 1.0 CD B:LYS261 3.4 192.5 1.0 PB B:08T901 3.5 201.6 1.0 CE B:LYS261 3.5 192.5 1.0 N B:GLY258 3.7 204.5 1.0 O2B B:08T901 3.7 201.6 1.0 O1B B:08T901 3.7 201.6 1.0 CB B:PRO257 3.8 202.8 1.0 CG B:LYS261 3.8 192.5 1.0 C B:PRO257 4.0 202.8 1.0 CG B:ASN358 4.1 225.8 1.0 O B:PRO256 4.2 205.1 1.0 N B:PRO257 4.2 202.8 1.0 ND2 B:ASN358 4.3 225.8 1.0 MG B:MG902 4.4 201.3 1.0 C B:PRO256 4.5 205.1 1.0 O B:GLY255 4.9 210.3 1.0 O3A B:08T901 4.9 201.6 1.0 CA B:GLY258 4.9 204.5 1.0 NH2 C:ARG369 4.9 236.2 1.0 N B:THR259 4.9 197.5 1.0 NH2 C:ARG372 5.0 232.6 1.0

Fluorine binding site 9 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 6


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of CDC48-SHP1 Unfolding Native Substrate, Class 6 within 5.0Å range: probe atom residue distance (Å) B Occ B:F901 b:210.2 occ:1.00 F3 B:08T901 0.0 210.2 1.0 BE B:08T901 1.5 210.2 1.0 F2 B:08T901 2.5 210.2 1.0 F1 B:08T901 2.5 210.2 1.0 O3B B:08T901 2.6 201.6 1.0 NH2 C:ARG372 2.9 232.6 1.0 NH1 C:ARG372 3.1 232.6 1.0 NH2 C:ARG369 3.1 236.2 1.0 NE C:ARG369 3.2 236.2 1.0 CB B:PRO257 3.2 202.8 1.0 CZ C:ARG372 3.4 232.6 1.0 CZ C:ARG369 3.6 236.2 1.0 N B:GLY258 3.6 204.5 1.0 CA B:PRO257 3.6 202.8 1.0 PB B:08T901 4.0 201.6 1.0 C B:PRO257 4.2 202.8 1.0 MG B:MG902 4.2 201.3 1.0 CD C:ARG369 4.3 236.2 1.0 O2B B:08T901 4.4 201.6 1.0 ND2 B:ASN358 4.6 225.8 1.0 CG B:PRO257 4.6 202.8 1.0 NE C:ARG372 4.7 232.6 1.0 CA B:GLY258 4.7 204.5 1.0 OD1 B:ASN358 4.7 225.8 1.0 O3A B:08T901 4.8 201.6 1.0 NH1 C:ARG369 4.9 236.2 1.0 O1B B:08T901 4.9 201.6 1.0 N B:PRO257 4.9 202.8 1.0

Fluorine binding site 10 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 6


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 10 of CDC48-SHP1 Unfolding Native Substrate, Class 6 within 5.0Å range: probe atom residue distance (Å) B Occ B:F903 b:211.7 occ:1.00 F1 B:08T903 0.0 211.7 1.0 BE B:08T903 1.5 211.7 1.0 MG B:MG904 2.2 202.0 1.0 F3 B:08T903 2.5 211.7 1.0 F2 B:08T903 2.6 211.7 1.0 O3B B:08T903 2.6 199.8 1.0 NH2 C:ARG648 2.6 218.8 1.0 O3A B:08T903 3.0 199.8 1.0 PB B:08T903 3.0 199.8 1.0 O2B B:08T903 3.1 199.8 1.0 OG1 B:THR535 3.5 189.2 1.0 CZ C:ARG648 3.9 218.8 1.0 NH2 C:ARG645 4.0 217.6 1.0 O1A B:08T903 4.1 199.8 1.0 PA B:08T903 4.2 199.8 1.0 N B:GLY531 4.2 198.1 1.0 NH1 C:ARG648 4.4 218.8 1.0 CB C:ASP619 4.5 231.7 1.0 CB B:THR535 4.5 189.2 1.0 O1B B:08T903 4.5 199.8 1.0 OD2 C:ASP619 4.6 231.7 1.0 CA B:GLY531 4.7 198.1 1.0 NE C:ARG648 4.8 218.8 1.0 CZ C:ARG645 4.9 217.6 1.0 CG C:ASP619 5.0 231.7 1.0 O2A B:08T903 5.0 199.8 1.0

I.Cooney, H.L.Schubert, K.Cedeno, O.N.Fisher, R.Carson, J.C.Price, C.P.Hill, P.S.Shen. Visualization of the CDC48 Aaa+ Atpase Protein Unfolding Pathway. Nat Commun V. 15 7505 2024.
ISSN: ESSN 2041-1723
PubMed: 39209885
DOI: 10.1038/S41467-024-51835-3