Fluorine in PDB 8u9z: CDC48-SHP1 Unfolding Native Substrate, Class 7

All present enzymatic activity of CDC48-SHP1 Unfolding Native Substrate, Class 7:
3.6.4.6;

The structure of CDC48-SHP1 Unfolding Native Substrate, Class 7 also contains other interesting chemical elements:

Magnesium

(Mg)

6 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 18;

Binding sites:

The binding sites of Fluorine atom in the CDC48-SHP1 Unfolding Native Substrate, Class 7 (pdb code 8u9z). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 18 binding sites of Fluorine where determined in the CDC48-SHP1 Unfolding Native Substrate, Class 7, PDB code: 8u9z:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Fluorine binding site 1 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 7


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of CDC48-SHP1 Unfolding Native Substrate, Class 7 within 5.0Å range: probe atom residue distance (Å) B Occ A:F901 b:145.8 occ:1.00 F1 A:08T901 0.0 145.8 1.0 BE A:08T901 1.5 145.8 1.0 MG A:MG902 1.9 144.0 1.0 F3 A:08T901 2.5 145.8 1.0 F2 A:08T901 2.6 145.8 1.0 O2B A:08T901 2.6 154.8 1.0 O3B A:08T901 2.6 154.8 1.0 PB A:08T901 3.1 154.8 1.0 OG1 A:THR262 3.1 150.7 1.0 CG A:LYS261 3.9 141.0 1.0 NH2 B:ARG372 4.0 148.9 1.0 O3A A:08T901 4.2 154.8 1.0 CD A:LYS261 4.2 141.0 1.0 CB A:THR262 4.2 150.7 1.0 O1B A:08T901 4.2 154.8 1.0 O2A A:08T901 4.6 154.8 1.0 N A:THR262 4.7 150.7 1.0 OD2 A:ASP314 4.8 172.8 1.0

Fluorine binding site 2 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 7


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of CDC48-SHP1 Unfolding Native Substrate, Class 7 within 5.0Å range: probe atom residue distance (Å) B Occ A:F901 b:145.8 occ:1.00 F2 A:08T901 0.0 145.8 1.0 BE A:08T901 1.6 145.8 1.0 F3 A:08T901 2.5 145.8 1.0 F1 A:08T901 2.6 145.8 1.0 O3B A:08T901 2.6 154.8 1.0 CA A:PRO257 3.5 146.0 1.0 N A:GLY258 3.5 143.7 1.0 CD A:LYS261 3.5 141.0 1.0 PB A:08T901 3.6 154.8 1.0 CE A:LYS261 3.7 141.0 1.0 NZ A:LYS261 3.8 141.0 1.0 O2B A:08T901 3.9 154.8 1.0 CG A:LYS261 3.9 141.0 1.0 O1B A:08T901 3.9 154.8 1.0 C A:PRO257 4.0 146.0 1.0 CB A:PRO257 4.1 146.0 1.0 ND2 A:ASN358 4.3 175.9 1.0 MG A:MG902 4.3 144.0 1.0 O A:PRO256 4.3 142.4 1.0 N A:PRO257 4.5 146.0 1.0 CB A:ASN358 4.5 175.9 1.0 CA A:GLY258 4.7 143.7 1.0 C A:PRO256 4.8 142.4 1.0 CG A:ASN358 4.9 175.9 1.0 CA A:ASN358 4.9 175.9 1.0 O3A A:08T901 4.9 154.8 1.0

Fluorine binding site 3 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 7


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of CDC48-SHP1 Unfolding Native Substrate, Class 7 within 5.0Å range: probe atom residue distance (Å) B Occ A:F901 b:145.8 occ:1.00 F3 A:08T901 0.0 145.8 1.0 BE A:08T901 1.5 145.8 1.0 F2 A:08T901 2.5 145.8 1.0 F1 A:08T901 2.5 145.8 1.0 O3B A:08T901 2.6 154.8 1.0 NH2 B:ARG372 2.9 148.9 1.0 NH2 B:ARG369 3.7 150.2 1.0 MG A:MG902 3.9 144.0 1.0 PB A:08T901 4.0 154.8 1.0 N A:GLY258 4.0 143.7 1.0 CZ B:ARG372 4.0 148.9 1.0 CB A:PRO257 4.2 146.0 1.0 CA A:PRO257 4.3 146.0 1.0 O2B A:08T901 4.4 154.8 1.0 CZ B:ARG369 4.5 150.2 1.0 NE B:ARG369 4.5 150.2 1.0 NE B:ARG372 4.6 148.9 1.0 C A:PRO257 4.7 146.0 1.0 O3A A:08T901 4.7 154.8 1.0 NH1 B:ARG372 4.9 148.9 1.0 CA A:GLY258 4.9 143.7 1.0 ND2 A:ASN358 4.9 175.9 1.0 O1B A:08T901 5.0 154.8 1.0

Fluorine binding site 4 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 7


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of CDC48-SHP1 Unfolding Native Substrate, Class 7 within 5.0Å range: probe atom residue distance (Å) B Occ A:F903 b:124.3 occ:1.00 F1 A:08T903 0.0 124.3 1.0 BE A:08T903 1.5 124.3 1.0 MG A:MG904 2.2 124.5 1.0 F3 A:08T903 2.5 124.3 1.0 F2 A:08T903 2.6 124.3 1.0 O3B A:08T903 2.6 125.2 1.0 O2B A:08T903 2.9 125.2 1.0 PB A:08T903 3.3 125.2 1.0 NH2 B:ARG648 3.9 137.2 1.0 NH1 B:ARG645 3.9 128.8 1.0 OG1 A:THR535 4.1 117.0 1.0 O3A A:08T903 4.3 125.2 1.0 O1B A:08T903 4.5 125.2 1.0 NH1 B:ARG648 4.5 137.2 1.0 CZ B:ARG648 4.7 137.2 1.0 O1A A:08T903 4.8 125.2 1.0 NZ A:LYS534 4.8 128.1 1.0 N A:GLY531 4.9 127.0 1.0

Fluorine binding site 5 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 7


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of CDC48-SHP1 Unfolding Native Substrate, Class 7 within 5.0Å range: probe atom residue distance (Å) B Occ A:F903 b:124.3 occ:1.00 F2 A:08T903 0.0 124.3 1.0 BE A:08T903 1.6 124.3 1.0 NZ A:LYS534 2.4 128.1 1.0 F3 A:08T903 2.5 124.3 1.0 F1 A:08T903 2.6 124.3 1.0 O3B A:08T903 2.6 125.2 1.0 PB A:08T903 3.3 125.2 1.0 O2B A:08T903 3.5 125.2 1.0 CE A:LYS534 3.6 128.1 1.0 O1B A:08T903 3.6 125.2 1.0 CA A:PRO530 3.7 121.9 1.0 N A:GLY531 3.7 127.0 1.0 CD A:LYS534 3.8 128.1 1.0 O A:PRO529 4.0 126.2 1.0 MG A:MG904 4.1 124.5 1.0 C A:PRO530 4.2 121.9 1.0 ND2 A:ASN634 4.3 153.3 1.0 NH1 B:ARG645 4.4 128.8 1.0 CG A:LYS534 4.5 128.1 1.0 N A:PRO530 4.5 121.9 1.0 C A:PRO529 4.6 126.2 1.0 CB A:PRO530 4.6 121.9 1.0 CB A:ASN634 4.6 153.3 1.0 CB A:LYS534 4.7 128.1 1.0 CG A:ASN634 4.7 153.3 1.0 CA A:GLY531 4.8 127.0 1.0 O3A A:08T903 4.8 125.2 1.0 CA A:ASN634 4.8 153.3 1.0 O A:GLY528 4.9 133.3 1.0

Fluorine binding site 6 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 7


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of CDC48-SHP1 Unfolding Native Substrate, Class 7 within 5.0Å range: probe atom residue distance (Å) B Occ A:F903 b:124.3 occ:1.00 F3 A:08T903 0.0 124.3 1.0 BE A:08T903 1.5 124.3 1.0 F2 A:08T903 2.5 124.3 1.0 F1 A:08T903 2.5 124.3 1.0 NH1 B:ARG645 2.6 128.8 1.0 O3B A:08T903 2.6 125.2 1.0 N A:GLY531 3.3 127.0 1.0 CA A:PRO530 3.3 121.9 1.0 CB A:PRO530 3.4 121.9 1.0 NH1 B:ARG648 3.6 137.2 1.0 ND2 A:ASN634 3.8 153.3 1.0 C A:PRO530 3.8 121.9 1.0 CZ B:ARG645 3.9 128.8 1.0 PB A:08T903 4.0 125.2 1.0 MG A:MG904 4.3 124.5 1.0 NH2 B:ARG648 4.4 137.2 1.0 CA A:GLY531 4.4 127.0 1.0 CZ B:ARG648 4.5 137.2 1.0 O2B A:08T903 4.5 125.2 1.0 N A:PRO530 4.6 121.9 1.0 CD B:ARG645 4.6 128.8 1.0 NZ A:LYS534 4.6 128.1 1.0 CG A:PRO530 4.6 121.9 1.0 NE B:ARG645 4.7 128.8 1.0 NH2 B:ARG645 4.7 128.8 1.0 CG A:ASN634 4.8 153.3 1.0 O1B A:08T903 4.8 125.2 1.0 CB B:ALA642 4.9 135.4 1.0 O3A A:08T903 4.9 125.2 1.0

Fluorine binding site 7 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 7


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of CDC48-SHP1 Unfolding Native Substrate, Class 7 within 5.0Å range: probe atom residue distance (Å) B Occ B:F901 b:128.4 occ:1.00 F1 B:08T901 0.0 128.4 1.0 BE B:08T901 1.5 128.4 1.0 MG B:MG902 2.1 123.4 1.0 F3 B:08T901 2.5 128.4 1.0 F2 B:08T901 2.6 128.4 1.0 O3B B:08T901 2.6 145.5 1.0 O2B B:08T901 2.7 145.5 1.0 PB B:08T901 3.0 145.5 1.0 O1A B:08T901 3.3 145.5 1.0 OG1 B:THR262 3.6 113.0 1.0 O3A B:08T901 3.6 145.5 1.0 PA B:08T901 4.0 145.5 1.0 NH2 C:ARG369 4.0 132.2 1.0 OD2 C:ASP343 4.3 132.7 1.0 O2A B:08T901 4.4 145.5 1.0 O1B B:08T901 4.5 145.5 1.0 CB B:THR262 4.6 113.0 1.0 NH2 C:ARG372 4.7 133.7 1.0 CE B:LYS261 4.8 119.1 1.0 CG C:ASP343 4.9 132.7 1.0 N B:THR262 5.0 113.0 1.0

Fluorine binding site 8 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 7


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of CDC48-SHP1 Unfolding Native Substrate, Class 7 within 5.0Å range: probe atom residue distance (Å) B Occ B:F901 b:128.4 occ:1.00 F2 B:08T901 0.0 128.4 1.0 BE B:08T901 1.6 128.4 1.0 F3 B:08T901 2.5 128.4 1.0 F1 B:08T901 2.6 128.4 1.0 O3B B:08T901 2.6 145.5 1.0 ND2 B:ASN358 2.8 135.9 1.0 OD1 B:ASN358 3.0 135.9 1.0 CG B:ASN358 3.2 135.9 1.0 O2B B:08T901 3.5 145.5 1.0 PB B:08T901 3.6 145.5 1.0 CE B:LYS261 3.6 119.1 1.0 NZ B:LYS261 3.8 119.1 1.0 CA B:PRO257 3.8 114.8 1.0 CB B:PRO257 4.0 114.8 1.0 MG B:MG902 4.3 123.4 1.0 O1B B:08T901 4.4 145.5 1.0 OE2 B:GLU315 4.5 144.3 1.0 N B:PRO257 4.6 114.8 1.0 N B:GLY258 4.7 124.3 1.0 CB B:ASN358 4.7 135.9 1.0 O3A B:08T901 4.8 145.5 1.0 C B:PRO257 4.8 114.8 1.0 O B:PRO256 4.9 122.5 1.0

Fluorine binding site 9 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 7


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of CDC48-SHP1 Unfolding Native Substrate, Class 7 within 5.0Å range: probe atom residue distance (Å) B Occ B:F901 b:128.4 occ:1.00 F3 B:08T901 0.0 128.4 1.0 BE B:08T901 1.5 128.4 1.0 F2 B:08T901 2.5 128.4 1.0 F1 B:08T901 2.5 128.4 1.0 O3B B:08T901 2.6 145.5 1.0 NH2 C:ARG369 2.9 132.2 1.0 NH2 C:ARG372 3.3 133.7 1.0 NE C:ARG369 3.5 132.2 1.0 NH1 C:ARG372 3.5 133.7 1.0 CZ C:ARG369 3.6 132.2 1.0 CB B:PRO257 3.7 114.8 1.0 CZ C:ARG372 3.9 133.7 1.0 PB B:08T901 4.0 145.5 1.0 CA B:PRO257 4.0 114.8 1.0 N B:GLY258 4.1 124.3 1.0 MG B:MG902 4.3 123.4 1.0 OD2 C:ASP343 4.3 132.7 1.0 O1A B:08T901 4.4 145.5 1.0 O2B B:08T901 4.4 145.5 1.0 ND2 B:ASN358 4.5 135.9 1.0 O3A B:08T901 4.5 145.5 1.0 C B:PRO257 4.6 114.8 1.0 NH1 C:ARG369 4.8 132.2 1.0 CD C:ARG369 4.8 132.2 1.0 OD1 B:ASN358 4.8 135.9 1.0 CD1 C:LEU339 4.9 125.5 1.0

Fluorine binding site 10 out of 18 in the CDC48-SHP1 Unfolding Native Substrate, Class 7


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 10 of CDC48-SHP1 Unfolding Native Substrate, Class 7 within 5.0Å range: probe atom residue distance (Å) B Occ B:F903 b:119.1 occ:1.00 F1 B:08T903 0.0 119.1 1.0 BE B:08T903 1.5 119.1 1.0 MG B:MG904 2.0 119.6 1.0 F3 B:08T903 2.5 119.1 1.0 O2B B:08T903 2.5 109.9 1.0 F2 B:08T903 2.6 119.1 1.0 O3B B:08T903 2.6 109.9 1.0 PB B:08T903 3.0 109.9 1.0 OG1 B:THR535 3.4 120.8 1.0 O3A B:08T903 3.8 109.9 1.0 OE2 B:GLU588 4.2 143.4 1.0 NH1 C:ARG648 4.2 125.2 1.0 NH1 C:ARG645 4.3 120.2 1.0 O1B B:08T903 4.4 109.9 1.0 NH2 C:ARG648 4.5 125.2 1.0 CG B:LYS534 4.6 123.7 1.0 CB B:THR535 4.6 120.8 1.0 CD B:LYS534 4.7 123.7 1.0 CZ C:ARG648 4.8 125.2 1.0 CE B:LYS534 4.9 123.7 1.0 N B:GLY531 5.0 126.0 1.0

I.Cooney, H.L.Schubert, K.Cedeno, O.N.Fisher, R.Carson, J.C.Price, C.P.Hill, P.S.Shen. Visualization of the CDC48 Aaa+ Atpase Protein Unfolding Pathway. Nat Commun V. 15 7505 2024.
ISSN: ESSN 2041-1723
PubMed: 39209885
DOI: 10.1038/S41467-024-51835-3