Fluorine in PDB 8ua0: CDC48-SHP1 Unfolding Native Substrate, Class 8

All present enzymatic activity of CDC48-SHP1 Unfolding Native Substrate, Class 8:
3.6.4.6;

The structure of CDC48-SHP1 Unfolding Native Substrate, Class 8 also contains other interesting chemical elements:

Magnesium

(Mg)

7 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 21;

Binding sites:

The binding sites of Fluorine atom in the CDC48-SHP1 Unfolding Native Substrate, Class 8 (pdb code 8ua0). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 21 binding sites of Fluorine where determined in the CDC48-SHP1 Unfolding Native Substrate, Class 8, PDB code: 8ua0:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Fluorine binding site 1 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 8


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of CDC48-SHP1 Unfolding Native Substrate, Class 8 within 5.0Å range: probe atom residue distance (Å) B Occ A:F901 b:114.7 occ:1.00 F1 A:08T901 0.0 114.7 1.0 BE A:08T901 1.5 114.7 1.0 MG A:MG902 2.1 108.9 1.0 F3 A:08T901 2.5 114.7 1.0 F2 A:08T901 2.6 114.7 1.0 O3B A:08T901 2.6 109.4 1.0 O2B A:08T901 2.8 109.4 1.0 PB A:08T901 3.2 109.4 1.0 ND2 A:ASN358 3.4 126.9 1.0 NH2 B:ARG372 3.7 112.8 1.0 OG1 A:THR262 3.9 112.9 1.0 NH2 B:ARG369 4.2 112.6 1.0 CG A:ASN358 4.3 126.9 1.0 CE A:LYS261 4.3 108.1 1.0 OD1 A:ASN358 4.3 126.9 1.0 O1B A:08T901 4.3 109.4 1.0 O3A A:08T901 4.3 109.4 1.0 OE2 A:GLU315 4.6 125.6 1.0 CZ B:ARG372 4.8 112.8 1.0 NZ A:LYS261 4.8 108.1 1.0 N A:GLY258 4.9 108.0 1.0 NH1 B:ARG372 5.0 112.8 1.0

Fluorine binding site 2 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 8


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of CDC48-SHP1 Unfolding Native Substrate, Class 8 within 5.0Å range: probe atom residue distance (Å) B Occ A:F901 b:114.7 occ:1.00 F2 A:08T901 0.0 114.7 1.0 BE A:08T901 1.6 114.7 1.0 ND2 A:ASN358 2.4 126.9 1.0 F3 A:08T901 2.5 114.7 1.0 F1 A:08T901 2.6 114.7 1.0 O3B A:08T901 2.6 109.4 1.0 NZ A:LYS261 2.9 108.1 1.0 CE A:LYS261 3.1 108.1 1.0 CA A:PRO257 3.1 103.7 1.0 N A:GLY258 3.3 108.0 1.0 PB A:08T901 3.4 109.4 1.0 CG A:ASN358 3.6 126.9 1.0 O1B A:08T901 3.6 109.4 1.0 O2B A:08T901 3.7 109.4 1.0 C A:PRO257 3.7 103.7 1.0 O A:PRO256 3.8 100.4 1.0 CB A:PRO257 4.0 103.7 1.0 N A:PRO257 4.0 103.7 1.0 C A:PRO256 4.3 100.4 1.0 OD1 A:ASN358 4.3 126.9 1.0 MG A:MG902 4.4 108.9 1.0 CB A:ASN358 4.4 126.9 1.0 CD A:LYS261 4.5 108.1 1.0 CA A:GLY258 4.5 108.0 1.0 O A:GLY255 4.8 109.3 1.0 N A:THR259 4.8 106.4 1.0 O3A A:08T901 4.9 109.4 1.0 NH2 B:ARG369 4.9 112.6 1.0 CG A:LYS261 4.9 108.1 1.0 CA A:ASN358 4.9 126.9 1.0 O A:PRO257 4.9 103.7 1.0

Fluorine binding site 3 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 8


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of CDC48-SHP1 Unfolding Native Substrate, Class 8 within 5.0Å range: probe atom residue distance (Å) B Occ A:F901 b:114.7 occ:1.00 F3 A:08T901 0.0 114.7 1.0 BE A:08T901 1.5 114.7 1.0 F2 A:08T901 2.5 114.7 1.0 F1 A:08T901 2.5 114.7 1.0 O3B A:08T901 2.6 109.4 1.0 ND2 A:ASN358 2.8 126.9 1.0 NH2 B:ARG369 3.1 112.6 1.0 NH2 B:ARG372 3.1 112.8 1.0 NH1 B:ARG372 3.1 112.8 1.0 CB A:PRO257 3.5 103.7 1.0 CZ B:ARG372 3.6 112.8 1.0 N A:GLY258 3.6 108.0 1.0 CA A:PRO257 3.6 103.7 1.0 PB A:08T901 4.0 109.4 1.0 CG A:ASN358 4.1 126.9 1.0 C A:PRO257 4.1 103.7 1.0 CZ B:ARG369 4.1 112.6 1.0 NE B:ARG369 4.2 112.6 1.0 MG A:MG902 4.4 108.9 1.0 O2B A:08T901 4.5 109.4 1.0 OD1 A:ASN358 4.6 126.9 1.0 CA A:GLY258 4.6 108.0 1.0 CB B:ALA366 4.9 102.8 1.0 O1B A:08T901 4.9 109.4 1.0 NE B:ARG372 4.9 112.8 1.0 O3A A:08T901 4.9 109.4 1.0 N A:PRO257 5.0 103.7 1.0

Fluorine binding site 4 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 8


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of CDC48-SHP1 Unfolding Native Substrate, Class 8 within 5.0Å range: probe atom residue distance (Å) B Occ A:F903 b:103.0 occ:1.00 F1 A:08T903 0.0 103.0 1.0 BE A:08T903 1.5 103.0 1.0 MG A:MG904 2.0 106.4 1.0 F3 A:08T903 2.5 103.0 1.0 F2 A:08T903 2.6 103.0 1.0 O3B A:08T903 2.6 98.8 1.0 O2B A:08T903 2.9 98.8 1.0 OG1 A:THR535 3.0 92.5 1.0 PB A:08T903 3.2 98.8 1.0 NH2 B:ARG648 3.5 102.1 1.0 O3A A:08T903 3.8 98.8 1.0 OE2 A:GLU588 4.0 125.0 1.0 CB A:THR535 4.0 92.5 1.0 O1A A:08T903 4.1 98.8 1.0 NH2 B:ARG645 4.5 97.7 1.0 PA A:08T903 4.6 98.8 1.0 OD2 A:ASP587 4.6 121.0 1.0 O1B A:08T903 4.6 98.8 1.0 N A:THR535 4.8 92.5 1.0 CZ B:ARG648 4.8 102.1 1.0 O B:ASP619 4.9 124.6 1.0 OD1 A:ASP587 4.9 121.0 1.0 CG2 A:THR535 5.0 92.5 1.0

Fluorine binding site 5 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 8


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of CDC48-SHP1 Unfolding Native Substrate, Class 8 within 5.0Å range: probe atom residue distance (Å) B Occ A:F903 b:103.0 occ:1.00 F2 A:08T903 0.0 103.0 1.0 BE A:08T903 1.6 103.0 1.0 F3 A:08T903 2.5 103.0 1.0 F1 A:08T903 2.6 103.0 1.0 O3B A:08T903 2.6 98.8 1.0 O2B A:08T903 3.3 98.8 1.0 PB A:08T903 3.4 98.8 1.0 OE2 A:GLU588 3.5 125.0 1.0 CE A:LYS534 3.8 92.6 1.0 MG A:MG904 3.9 106.4 1.0 CB A:ASN634 4.1 108.9 1.0 O1B A:08T903 4.2 98.8 1.0 ND2 A:ASN634 4.2 108.9 1.0 CG A:ASN634 4.3 108.9 1.0 CD A:GLU588 4.6 125.0 1.0 NH2 B:ARG648 4.6 102.1 1.0 N A:ASN634 4.7 108.9 1.0 CD A:LYS534 4.7 92.6 1.0 CA A:PRO530 4.7 88.5 1.0 O3A A:08T903 4.8 98.8 1.0 NZ A:LYS534 4.8 92.6 1.0 CA A:ASN634 4.9 108.9 1.0 OG1 A:THR535 4.9 92.5 1.0 OD1 A:ASN634 5.0 108.9 1.0 OE1 A:GLU588 5.0 125.0 1.0

Fluorine binding site 6 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 8


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of CDC48-SHP1 Unfolding Native Substrate, Class 8 within 5.0Å range: probe atom residue distance (Å) B Occ A:F903 b:103.0 occ:1.00 F3 A:08T903 0.0 103.0 1.0 BE A:08T903 1.5 103.0 1.0 NH2 B:ARG648 2.3 102.1 1.0 F2 A:08T903 2.5 103.0 1.0 F1 A:08T903 2.5 103.0 1.0 O3B A:08T903 2.6 98.8 1.0 CZ B:ARG648 3.4 102.1 1.0 NH2 B:ARG645 3.7 97.7 1.0 NE B:ARG648 3.7 102.1 1.0 PB A:08T903 4.0 98.8 1.0 MG A:MG904 4.1 106.4 1.0 NE B:ARG645 4.2 97.7 1.0 OE2 A:GLU588 4.2 125.0 1.0 CZ B:ARG645 4.4 97.7 1.0 ND2 A:ASN634 4.5 108.9 1.0 O2B A:08T903 4.5 98.8 1.0 NH1 B:ARG648 4.5 102.1 1.0 O3A A:08T903 4.7 98.8 1.0 CB A:PRO530 4.8 88.5 1.0 CD2 B:LEU615 4.8 109.5 1.0 O B:ALA642 4.9 95.7 1.0

Fluorine binding site 7 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 8


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of CDC48-SHP1 Unfolding Native Substrate, Class 8 within 5.0Å range: probe atom residue distance (Å) B Occ B:F901 b:101.3 occ:1.00 F1 B:08T901 0.0 101.3 1.0 BE B:08T901 1.5 101.3 1.0 MG B:MG902 2.0 113.2 1.0 F3 B:08T901 2.5 101.3 1.0 F2 B:08T901 2.6 101.3 1.0 O3B B:08T901 2.6 97.4 1.0 O2B B:08T901 2.8 97.4 1.0 OG1 B:THR262 3.0 95.4 1.0 PB B:08T901 3.2 97.4 1.0 NH2 C:ARG372 4.0 98.0 1.0 CB B:THR262 4.1 95.4 1.0 O3A B:08T901 4.4 97.4 1.0 O1B B:08T901 4.4 97.4 1.0 N B:THR262 4.4 95.4 1.0 O B:PRO257 4.4 94.2 1.0 OE2 B:GLU315 4.4 107.3 1.0 CE B:LYS261 4.6 92.9 1.0 OD1 B:ASP314 4.8 107.9 1.0 CB B:LYS261 4.9 92.9 1.0 CA B:THR262 4.9 95.4 1.0 NH2 C:ARG369 4.9 102.8 1.0

Fluorine binding site 8 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 8


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of CDC48-SHP1 Unfolding Native Substrate, Class 8 within 5.0Å range: probe atom residue distance (Å) B Occ B:F901 b:101.3 occ:1.00 F2 B:08T901 0.0 101.3 1.0 BE B:08T901 1.6 101.3 1.0 O B:PRO257 2.4 94.2 1.0 F3 B:08T901 2.5 101.3 1.0 F1 B:08T901 2.6 101.3 1.0 O3B B:08T901 2.6 97.4 1.0 OD1 B:ASN358 2.9 98.1 1.0 NZ B:LYS261 3.1 92.9 1.0 CE B:LYS261 3.2 92.9 1.0 PB B:08T901 3.4 97.4 1.0 C B:PRO257 3.4 94.2 1.0 O1B B:08T901 3.6 97.4 1.0 O2B B:08T901 3.7 97.4 1.0 CA B:PRO257 3.8 94.2 1.0 CG B:ASN358 3.8 98.1 1.0 MG B:MG902 3.9 113.2 1.0 ND2 B:ASN358 4.0 98.1 1.0 O B:PRO256 4.2 95.7 1.0 CD B:LYS261 4.6 92.9 1.0 N B:GLY258 4.6 93.3 1.0 OE2 B:GLU315 4.8 107.3 1.0 CB B:PRO257 4.8 94.2 1.0 O3A B:08T901 4.8 97.4 1.0 N B:PRO257 4.8 94.2 1.0 NH2 C:ARG372 4.9 98.0 1.0 C B:PRO256 4.9 95.7 1.0 CB B:LYS261 4.9 92.9 1.0 CG B:LYS261 5.0 92.9 1.0

Fluorine binding site 9 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 8


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of CDC48-SHP1 Unfolding Native Substrate, Class 8 within 5.0Å range: probe atom residue distance (Å) B Occ B:F901 b:101.3 occ:1.00 F3 B:08T901 0.0 101.3 1.0 BE B:08T901 1.5 101.3 1.0 NH2 C:ARG372 2.4 98.0 1.0 F2 B:08T901 2.5 101.3 1.0 F1 B:08T901 2.5 101.3 1.0 O3B B:08T901 2.6 97.4 1.0 CZ C:ARG372 3.3 98.0 1.0 NH1 C:ARG372 3.4 98.0 1.0 O B:PRO257 3.6 94.2 1.0 MG B:MG902 3.7 113.2 1.0 NH2 C:ARG369 3.8 102.8 1.0 PB B:08T901 4.0 97.4 1.0 NE C:ARG369 4.1 102.8 1.0 OE2 B:GLU315 4.3 107.3 1.0 C B:PRO257 4.4 94.2 1.0 CZ C:ARG369 4.4 102.8 1.0 ND2 B:ASN358 4.4 98.1 1.0 OD1 B:ASN358 4.5 98.1 1.0 O2B B:08T901 4.5 97.4 1.0 NE C:ARG372 4.6 98.0 1.0 CA B:PRO257 4.8 94.2 1.0 O1B B:08T901 4.8 97.4 1.0 O3A B:08T901 4.9 97.4 1.0 CG B:ASN358 4.9 98.1 1.0

Fluorine binding site 10 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 8


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 10 of CDC48-SHP1 Unfolding Native Substrate, Class 8 within 5.0Å range: probe atom residue distance (Å) B Occ B:F903 b:102.9 occ:1.00 F1 B:08T903 0.0 102.9 1.0 BE B:08T903 1.5 102.9 1.0 MG B:MG904 2.1 102.5 1.0 F3 B:08T903 2.5 102.9 1.0 F2 B:08T903 2.6 102.9 1.0 O3B B:08T903 2.6 89.7 1.0 O2B B:08T903 2.9 89.7 1.0 OE2 B:GLU588 2.9 112.1 1.0 PB B:08T903 3.2 89.7 1.0 NH2 C:ARG648 3.5 95.6 1.0 OG1 B:THR535 4.1 90.3 1.0 CD B:GLU588 4.2 112.1 1.0 O1B B:08T903 4.2 89.7 1.0 O3A B:08T903 4.5 89.7 1.0 CZ C:ARG648 4.6 95.6 1.0 CE B:LYS534 4.8 88.8 1.0 NH1 C:ARG648 4.8 95.6 1.0 OD1 B:ASP587 4.9 113.8 1.0 CG B:GLU588 5.0 112.1 1.0 OE1 B:GLU588 5.0 112.1 1.0

I.Cooney, H.L.Schubert, K.Cedeno, O.N.Fisher, R.Carson, J.C.Price, C.P.Hill, P.S.Shen. Visualization of the CDC48 Aaa+ Atpase Protein Unfolding Pathway. Nat Commun V. 15 7505 2024.
ISSN: ESSN 2041-1723
PubMed: 39209885
DOI: 10.1038/S41467-024-51835-3