Fluorine in PDB 8ua1: CDC48-SHP1 Unfolding Native Substrate, Class 9

All present enzymatic activity of CDC48-SHP1 Unfolding Native Substrate, Class 9:
3.6.4.6;

The structure of CDC48-SHP1 Unfolding Native Substrate, Class 9 also contains other interesting chemical elements:

Magnesium

(Mg)

7 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 21;

Binding sites:

The binding sites of Fluorine atom in the CDC48-SHP1 Unfolding Native Substrate, Class 9 (pdb code 8ua1). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 21 binding sites of Fluorine where determined in the CDC48-SHP1 Unfolding Native Substrate, Class 9, PDB code: 8ua1:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Fluorine binding site 1 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 9


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of CDC48-SHP1 Unfolding Native Substrate, Class 9 within 5.0Å range: probe atom residue distance (Å) B Occ A:F901 b:91.0 occ:1.00 F1 A:08T901 0.0 91.0 1.0 BE A:08T901 1.5 86.3 1.0 MG A:MG902 2.0 86.3 1.0 O2B A:08T901 2.5 83.8 1.0 F3 A:08T901 2.5 87.4 1.0 O3B A:08T901 2.5 81.2 1.0 F2 A:08T901 2.6 89.7 1.0 PB A:08T901 3.0 77.5 1.0 OG1 A:THR262 3.7 83.8 1.0 O3A A:08T901 4.0 80.4 1.0 O1B A:08T901 4.2 77.7 1.0 NH2 B:ARG372 4.5 82.8 1.0 OE2 A:GLU315 4.6 128.4 1.0 NH1 B:ARG372 4.8 78.5 1.0 CB A:THR262 4.8 80.3 1.0 CD A:LYS261 4.9 67.7 1.0 CB A:LYS261 4.9 66.7 1.0 N A:THR262 4.9 78.5 1.0 O2A A:08T901 5.0 86.3 1.0

Fluorine binding site 2 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 9


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of CDC48-SHP1 Unfolding Native Substrate, Class 9 within 5.0Å range: probe atom residue distance (Å) B Occ A:F901 b:89.7 occ:1.00 F2 A:08T901 0.0 89.7 1.0 BE A:08T901 1.6 86.3 1.0 F3 A:08T901 2.5 87.4 1.0 F1 A:08T901 2.6 91.0 1.0 O3B A:08T901 2.6 81.2 1.0 NZ A:LYS261 2.8 76.6 1.0 PB A:08T901 3.4 77.5 1.0 CD A:LYS261 3.4 67.7 1.0 O2B A:08T901 3.5 83.8 1.0 CA A:PRO257 3.7 72.9 1.0 N A:GLY258 3.7 78.2 1.0 CE A:LYS261 3.7 71.3 1.0 O1B A:08T901 3.7 77.7 1.0 O A:PRO256 4.0 72.6 1.0 C A:PRO257 4.2 76.2 1.0 CG A:LYS261 4.2 66.3 1.0 MG A:MG902 4.4 86.3 1.0 N A:PRO257 4.5 73.7 1.0 CB A:PRO257 4.5 78.0 1.0 CB A:LYS261 4.6 66.7 1.0 C A:PRO256 4.6 72.9 1.0 CB A:ASN358 4.7 97.9 1.0 CA A:GLY258 4.8 80.4 1.0 O3A A:08T901 4.8 80.4 1.0 N A:THR259 4.8 71.5 1.0 O A:GLY255 4.9 84.0 1.0

Fluorine binding site 3 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 9


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of CDC48-SHP1 Unfolding Native Substrate, Class 9 within 5.0Å range: probe atom residue distance (Å) B Occ A:F901 b:87.4 occ:1.00 F3 A:08T901 0.0 87.4 1.0 BE A:08T901 1.5 86.3 1.0 F2 A:08T901 2.5 89.7 1.0 F1 A:08T901 2.5 91.0 1.0 O3B A:08T901 2.6 81.2 1.0 N A:GLY258 3.6 78.2 1.0 CA A:PRO257 3.6 72.9 1.0 CB A:PRO257 3.7 78.0 1.0 NH1 B:ARG372 3.7 78.5 1.0 PB A:08T901 4.0 77.5 1.0 CD B:ARG369 4.1 77.2 1.0 C A:PRO257 4.1 76.2 1.0 NE B:ARG369 4.2 79.1 1.0 O2B A:08T901 4.4 83.8 1.0 MG A:MG902 4.4 86.3 1.0 CZ B:ARG369 4.5 84.8 1.0 NH2 B:ARG372 4.6 82.8 1.0 CA A:GLY258 4.6 80.4 1.0 CZ B:ARG372 4.6 79.3 1.0 NH1 B:ARG369 4.7 86.0 1.0 O3A A:08T901 4.8 80.4 1.0 O1B A:08T901 4.9 77.7 1.0 N A:PRO257 4.9 73.7 1.0

Fluorine binding site 4 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 9


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of CDC48-SHP1 Unfolding Native Substrate, Class 9 within 5.0Å range: probe atom residue distance (Å) B Occ A:F903 b:75.2 occ:1.00 F1 A:08T903 0.0 75.2 1.0 BE A:08T903 1.5 78.7 1.0 MG A:MG904 1.8 76.8 1.0 F3 A:08T903 2.5 83.3 1.0 F2 A:08T903 2.5 85.3 1.0 O3B A:08T903 2.6 75.6 1.0 O2B A:08T903 2.6 75.0 1.0 PB A:08T903 3.1 79.0 1.0 NH2 B:ARG648 3.4 81.5 1.0 OG1 A:THR535 3.7 76.2 1.0 O3A A:08T903 3.9 74.5 1.0 OE2 A:GLU588 4.1 107.0 1.0 O1A A:08T903 4.2 76.1 1.0 O1B A:08T903 4.4 75.3 1.0 CZ B:ARG648 4.4 73.1 1.0 OD1 A:ASN634 4.5 96.9 1.0 NH1 B:ARG648 4.6 71.7 1.0 PA A:08T903 4.7 69.6 1.0 CB A:THR535 4.9 71.7 1.0 CD A:LYS534 5.0 69.5 1.0

Fluorine binding site 5 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 9


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of CDC48-SHP1 Unfolding Native Substrate, Class 9 within 5.0Å range: probe atom residue distance (Å) B Occ A:F903 b:85.3 occ:1.00 F2 A:08T903 0.0 85.3 1.0 BE A:08T903 1.6 78.7 1.0 F3 A:08T903 2.5 83.3 1.0 F1 A:08T903 2.5 75.2 1.0 O3B A:08T903 2.6 75.6 1.0 OD1 A:ASN634 2.6 96.9 1.0 ND2 A:ASN634 2.7 90.1 1.0 CG A:ASN634 3.0 91.2 1.0 PB A:08T903 3.4 79.0 1.0 O2B A:08T903 3.4 75.0 1.0 O1B A:08T903 3.9 75.3 1.0 OE2 A:GLU588 3.9 107.0 1.0 CE A:LYS534 4.0 67.5 1.0 CA A:PRO530 4.0 68.2 1.0 MG A:MG904 4.0 76.8 1.0 CD A:LYS534 4.0 69.5 1.0 CB A:PRO530 4.4 70.1 1.0 CB A:ASN634 4.4 91.3 1.0 N A:GLY531 4.5 72.8 1.0 O3A A:08T903 4.8 74.5 1.0 C A:PRO530 4.9 74.7 1.0 NH2 B:ARG648 4.9 81.5 1.0 N A:PRO530 4.9 68.5 1.0 CA A:ASN634 4.9 90.1 1.0 O A:PRO529 4.9 72.0 1.0 N A:ASN634 5.0 84.8 1.0

Fluorine binding site 6 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 9


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of CDC48-SHP1 Unfolding Native Substrate, Class 9 within 5.0Å range: probe atom residue distance (Å) B Occ A:F903 b:83.3 occ:1.00 F3 A:08T903 0.0 83.3 1.0 BE A:08T903 1.5 78.7 1.0 F2 A:08T903 2.5 85.3 1.0 F1 A:08T903 2.5 75.2 1.0 NH1 B:ARG648 2.5 71.7 1.0 O3B A:08T903 2.6 75.6 1.0 NH2 B:ARG648 2.7 81.5 1.0 CZ B:ARG648 3.0 73.1 1.0 ND2 A:ASN634 3.7 90.1 1.0 NE B:ARG645 3.8 67.7 1.0 PB A:08T903 4.0 79.0 1.0 MG A:MG904 4.0 76.8 1.0 NH2 B:ARG645 4.1 78.7 1.0 OD1 A:ASN634 4.2 96.9 1.0 CZ B:ARG645 4.3 71.9 1.0 NE B:ARG648 4.4 71.0 1.0 CB A:PRO530 4.4 70.1 1.0 O2B A:08T903 4.4 75.0 1.0 CG A:ASN634 4.4 91.2 1.0 CD B:ARG645 4.7 68.5 1.0 N A:GLY531 4.7 72.8 1.0 CA A:PRO530 4.7 68.2 1.0 OE2 A:GLU588 4.7 107.0 1.0 O3A A:08T903 4.7 74.5 1.0 O B:ALA642 4.8 73.2 1.0 CB B:ALA642 4.8 71.6 1.0 O1B A:08T903 5.0 75.3 1.0

Fluorine binding site 7 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 9


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of CDC48-SHP1 Unfolding Native Substrate, Class 9 within 5.0Å range: probe atom residue distance (Å) B Occ B:F901 b:76.2 occ:1.00 F1 B:08T901 0.0 76.2 1.0 BE B:08T901 1.5 74.2 1.0 MG B:MG902 1.8 80.2 1.0 F3 B:08T901 2.5 73.5 1.0 O3B B:08T901 2.5 69.9 1.0 F2 B:08T901 2.6 77.4 1.0 O2B B:08T901 2.7 71.4 1.0 PB B:08T901 3.1 65.2 1.0 OG1 B:THR262 3.6 71.3 1.0 NH2 C:ARG372 3.8 72.0 1.0 O3A B:08T901 4.0 73.8 1.0 OE2 B:GLU315 4.4 100.1 1.0 O1B B:08T901 4.5 62.9 1.0 OD1 B:ASN358 4.6 73.0 1.0 CB B:THR262 4.6 66.8 1.0 NH2 C:ARG369 4.8 73.7 1.0 NZ B:LYS261 4.9 56.5 1.0 N B:THR262 4.9 61.9 1.0 CZ C:ARG372 5.0 69.4 1.0

Fluorine binding site 8 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 9


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of CDC48-SHP1 Unfolding Native Substrate, Class 9 within 5.0Å range: probe atom residue distance (Å) B Occ B:F901 b:77.4 occ:1.00 F2 B:08T901 0.0 77.4 1.0 BE B:08T901 1.6 74.2 1.0 NZ B:LYS261 2.5 56.5 1.0 F3 B:08T901 2.5 73.5 1.0 F1 B:08T901 2.6 76.2 1.0 O3B B:08T901 2.6 69.9 1.0 OD1 B:ASN358 2.9 73.0 1.0 O2B B:08T901 3.3 71.4 1.0 PB B:08T901 3.3 65.2 1.0 CE B:LYS261 3.6 53.4 1.0 CD B:LYS261 3.7 52.4 1.0 CA B:PRO257 3.7 62.3 1.0 O1B B:08T901 3.8 62.9 1.0 CG B:ASN358 3.8 69.7 1.0 N B:GLY258 3.8 63.6 1.0 MG B:MG902 4.0 80.2 1.0 ND2 B:ASN358 4.0 70.1 1.0 O B:PRO256 4.2 69.1 1.0 CG B:LYS261 4.3 53.3 1.0 C B:PRO257 4.3 63.4 1.0 CB B:PRO257 4.5 69.4 1.0 CB B:LYS261 4.5 54.3 1.0 N B:PRO257 4.6 63.9 1.0 O3A B:08T901 4.7 73.8 1.0 C B:PRO256 4.7 67.7 1.0 CA B:GLY258 4.9 67.3 1.0 N B:THR259 4.9 60.3 1.0

Fluorine binding site 9 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 9


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of CDC48-SHP1 Unfolding Native Substrate, Class 9 within 5.0Å range: probe atom residue distance (Å) B Occ B:F901 b:73.5 occ:1.00 F3 B:08T901 0.0 73.5 1.0 BE B:08T901 1.5 74.2 1.0 F2 B:08T901 2.5 77.4 1.0 F1 B:08T901 2.5 76.2 1.0 O3B B:08T901 2.6 69.9 1.0 NH2 C:ARG372 3.5 72.0 1.0 ND2 B:ASN358 3.6 70.1 1.0 NH1 C:ARG372 3.7 68.6 1.0 CB B:PRO257 3.7 69.4 1.0 N B:GLY258 3.7 63.6 1.0 CA B:PRO257 3.8 62.3 1.0 PB B:08T901 4.0 65.2 1.0 OD1 B:ASN358 4.0 73.0 1.0 NE C:ARG369 4.0 64.3 1.0 MG B:MG902 4.1 80.2 1.0 CZ C:ARG372 4.1 69.4 1.0 CG B:ASN358 4.2 69.7 1.0 C B:PRO257 4.3 63.4 1.0 O2B B:08T901 4.4 71.4 1.0 NH2 C:ARG369 4.5 73.7 1.0 OE2 B:GLU315 4.6 100.1 1.0 CZ C:ARG369 4.6 66.6 1.0 NZ B:LYS261 4.7 56.5 1.0 CD C:ARG369 4.8 64.9 1.0 CA B:GLY258 4.8 67.3 1.0 CB C:ALA366 4.8 65.5 1.0 O3A B:08T901 4.8 73.8 1.0 O1B B:08T901 4.9 62.9 1.0

Fluorine binding site 10 out of 21 in the CDC48-SHP1 Unfolding Native Substrate, Class 9


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 10 of CDC48-SHP1 Unfolding Native Substrate, Class 9 within 5.0Å range: probe atom residue distance (Å) B Occ B:F903 b:82.4 occ:1.00 F1 B:08T903 0.0 82.4 1.0 BE B:08T903 1.5 75.1 1.0 MG B:MG904 1.9 82.3 1.0 F3 B:08T903 2.5 73.8 1.0 O3B B:08T903 2.5 70.2 1.0 F2 B:08T903 2.6 77.8 1.0 O2B B:08T903 2.6 75.9 1.0 PB B:08T903 3.0 72.2 1.0 NH2 C:ARG648 3.5 72.0 1.0 OG1 B:THR535 3.6 78.2 1.0 O3A B:08T903 3.9 76.3 1.0 OE2 B:GLU588 4.1 95.1 1.0 O1B B:08T903 4.4 65.8 1.0 NH2 C:ARG645 4.6 78.5 1.0 CZ C:ARG648 4.7 69.6 1.0 CB B:THR535 4.9 73.1 1.0 NZ B:LYS534 5.0 66.1 1.0 N B:GLY531 5.0 70.7 1.0

I.Cooney, H.L.Schubert, K.Cedeno, O.N.Fisher, R.Carson, J.C.Price, C.P.Hill, P.S.Shen. Visualization of the CDC48 Aaa+ Atpase Protein Unfolding Pathway. Nat Commun V. 15 7505 2024.
ISSN: ESSN 2041-1723
PubMed: 39209885
DOI: 10.1038/S41467-024-51835-3