Fluorine in PDB 8utb: ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738

The structure of ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738 also contains other interesting chemical elements:

Chlorine

(Cl)

15 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 15;

Binding sites:

The binding sites of Fluorine atom in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738 (pdb code 8utb). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 15 binding sites of Fluorine where determined in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738, PDB code: 8utb:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Fluorine binding site 1 out of 15 in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738 within 5.0Å range: probe atom residue distance (Å) B Occ A:F601 b:59.3 occ:1.00 F A:XG3601 0.0 59.3 1.0 C6 A:XG3601 1.3 59.3 1.0 F1 A:XG3601 2.1 59.3 1.0 F2 A:XG3601 2.1 59.3 1.0 C5 A:XG3601 2.4 59.3 1.0 HE2 A:MET278 2.5 46.3 1.0 HE1 A:MET278 2.6 46.3 1.0 H A:XG3601 2.7 59.3 1.0 C A:XG3601 2.9 59.3 1.0 CE A:MET278 3.0 46.3 1.0 HB2 A:ALA275 3.2 48.2 1.0 HA A:ALA275 3.3 48.2 1.0 C4 A:XG3601 3.5 59.3 1.0 HE3 A:MET278 3.6 46.3 1.0 HB1 A:ALA275 3.7 48.2 1.0 H2 A:XG3601 3.8 59.3 1.0 CB A:ALA275 3.8 48.2 1.0 CA A:ALA275 4.0 48.2 1.0 C1 A:XG3601 4.2 59.3 1.0 HG22 B:ILE216 4.3 50.8 1.0 SD A:MET278 4.3 46.3 1.0 HG21 B:ILE216 4.4 50.8 1.0 HB3 A:MET278 4.4 46.3 1.0 C3 A:XG3601 4.7 59.3 1.0 HB3 A:ALA275 4.7 48.2 1.0 HB B:ILE216 4.7 50.8 1.0 CG2 B:ILE216 4.8 50.8 1.0 N A:ALA275 4.8 48.2 1.0 HD11 A:ILE279 4.9 43.6 1.0 H1 A:XG3601 4.9 59.3 1.0 HD3 B:PRO217 4.9 50.1 1.0 C2 A:XG3601 5.0 59.3 1.0

Fluorine binding site 2 out of 15 in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738 within 5.0Å range: probe atom residue distance (Å) B Occ A:F601 b:59.3 occ:1.00 F1 A:XG3601 0.0 59.3 1.0 C6 A:XG3601 1.3 59.3 1.0 F2 A:XG3601 2.1 59.3 1.0 F A:XG3601 2.1 59.3 1.0 C5 A:XG3601 2.4 59.3 1.0 HE1 A:MET278 2.5 46.3 1.0 HD3 B:PRO217 3.0 50.1 1.0 H A:XG3601 3.1 59.3 1.0 C A:XG3601 3.1 59.3 1.0 HB B:ILE216 3.2 50.8 1.0 C4 A:XG3601 3.3 59.3 1.0 HG22 B:ILE216 3.4 50.8 1.0 CE A:MET278 3.4 46.3 1.0 O B:LEU212 3.5 54.9 1.0 H2 A:XG3601 3.5 59.3 1.0 HE2 A:MET278 3.6 46.3 1.0 HD2 B:PRO217 3.7 50.1 1.0 CD B:PRO217 3.7 50.1 1.0 HG21 B:ILE216 3.9 50.8 1.0 CG2 B:ILE216 3.9 50.8 1.0 CB B:ILE216 4.0 50.8 1.0 HE3 A:MET278 4.0 46.3 1.0 HD13 B:ILE216 4.2 50.8 1.0 C1 A:XG3601 4.3 59.3 1.0 SD A:MET278 4.4 46.3 1.0 C3 A:XG3601 4.5 59.3 1.0 HG3 B:PRO217 4.6 50.1 1.0 HA B:ASN213 4.7 55.3 1.0 C B:LEU212 4.7 54.9 1.0 HG12 B:ILE216 4.7 50.8 1.0 N B:PRO217 4.8 50.1 1.0 CG B:PRO217 4.8 50.1 1.0 CG1 B:ILE216 4.8 50.8 1.0 HG23 B:ILE216 4.8 50.8 1.0 C2 A:XG3601 4.9 59.3 1.0 CD1 B:ILE216 4.9 50.8 1.0

Fluorine binding site 3 out of 15 in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738 within 5.0Å range: probe atom residue distance (Å) B Occ A:F601 b:59.3 occ:1.00 F2 A:XG3601 0.0 59.3 1.0 C6 A:XG3601 1.3 59.3 1.0 F1 A:XG3601 2.1 59.3 1.0 F A:XG3601 2.1 59.3 1.0 C5 A:XG3601 2.4 59.3 1.0 H2 A:XG3601 2.4 59.3 1.0 C4 A:XG3601 2.7 59.3 1.0 O B:LEU212 3.4 54.9 1.0 C A:XG3601 3.6 59.3 1.0 HD22 B:LEU212 3.8 54.9 1.0 HD13 B:ILE216 3.8 50.8 1.0 HB3 B:LEU212 3.9 54.9 1.0 H A:XG3601 4.0 59.3 1.0 HB B:ILE216 4.1 50.8 1.0 HB2 A:ALA275 4.1 48.2 1.0 C3 A:XG3601 4.1 59.3 1.0 HE1 A:MET278 4.1 46.3 1.0 C B:LEU212 4.4 54.9 1.0 O A:XG3601 4.4 59.3 1.0 HG21 B:ILE216 4.5 50.8 1.0 HA B:LEU212 4.5 54.9 1.0 HE2 A:MET278 4.6 46.3 1.0 HG12 B:ILE216 4.6 50.8 1.0 HG22 B:ILE216 4.6 50.8 1.0 CD2 B:LEU212 4.7 54.9 1.0 CB B:LEU212 4.7 54.9 1.0 CD1 B:ILE216 4.7 50.8 1.0 C1 A:XG3601 4.8 59.3 1.0 CB B:ILE216 4.8 50.8 1.0 CA B:LEU212 4.8 54.9 1.0 HD13 B:LEU212 4.8 54.9 1.0 CE A:MET278 4.8 46.3 1.0 CG2 B:ILE216 4.8 50.8 1.0 HB1 A:ALA275 4.9 48.2 1.0 CB A:ALA275 4.9 48.2 1.0 HD3 B:PRO217 4.9 50.1 1.0 CG1 B:ILE216 4.9 50.8 1.0 C2 A:XG3601 4.9 59.3 1.0

Fluorine binding site 4 out of 15 in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738 within 5.0Å range: probe atom residue distance (Å) B Occ B:F602 b:59.3 occ:1.00 F B:XG3602 0.0 59.3 1.0 C6 B:XG3602 1.3 59.3 1.0 F1 B:XG3602 2.1 59.3 1.0 F2 B:XG3602 2.1 59.3 1.0 C5 B:XG3602 2.4 59.3 1.0 HE2 B:MET278 2.6 46.5 1.0 HE1 B:MET278 2.6 46.5 1.0 H B:XG3602 2.7 59.3 1.0 C B:XG3602 2.9 59.3 1.0 CE B:MET278 3.0 46.5 1.0 HB2 B:ALA275 3.2 49.1 1.0 HA B:ALA275 3.3 49.1 1.0 C4 B:XG3602 3.5 59.3 1.0 HE3 B:MET278 3.6 46.5 1.0 HB1 B:ALA275 3.7 49.1 1.0 H2 B:XG3602 3.8 59.3 1.0 CB B:ALA275 3.8 49.1 1.0 CA B:ALA275 4.0 49.1 1.0 C1 B:XG3602 4.2 59.3 1.0 HG22 C:ILE216 4.3 50.5 1.0 SD B:MET278 4.3 46.5 1.0 HG21 C:ILE216 4.4 50.5 1.0 HB3 B:MET278 4.4 46.5 1.0 C3 B:XG3602 4.7 59.3 1.0 HB3 B:ALA275 4.7 49.1 1.0 HB C:ILE216 4.7 50.5 1.0 CG2 C:ILE216 4.8 50.5 1.0 N B:ALA275 4.8 49.1 1.0 HD11 B:ILE279 4.9 43.9 1.0 H1 B:XG3602 4.9 59.3 1.0 HD3 C:PRO217 4.9 49.6 1.0 C2 B:XG3602 5.0 59.3 1.0

Fluorine binding site 5 out of 15 in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738 within 5.0Å range: probe atom residue distance (Å) B Occ B:F602 b:59.3 occ:1.00 F1 B:XG3602 0.0 59.3 1.0 C6 B:XG3602 1.3 59.3 1.0 F2 B:XG3602 2.1 59.3 1.0 F B:XG3602 2.1 59.3 1.0 C5 B:XG3602 2.3 59.3 1.0 HE1 B:MET278 2.5 46.5 1.0 HD3 C:PRO217 3.0 49.6 1.0 H B:XG3602 3.1 59.3 1.0 C B:XG3602 3.1 59.3 1.0 HB C:ILE216 3.2 50.5 1.0 C4 B:XG3602 3.3 59.3 1.0 HG22 C:ILE216 3.3 50.5 1.0 CE B:MET278 3.4 46.5 1.0 O C:LEU212 3.5 54.3 1.0 H2 B:XG3602 3.5 59.3 1.0 HE2 B:MET278 3.6 46.5 1.0 HD2 C:PRO217 3.6 49.6 1.0 CD C:PRO217 3.7 49.6 1.0 HG21 C:ILE216 3.9 50.5 1.0 CG2 C:ILE216 3.9 50.5 1.0 CB C:ILE216 4.0 50.5 1.0 HE3 B:MET278 4.0 46.5 1.0 HD13 C:ILE216 4.2 50.5 1.0 C1 B:XG3602 4.3 59.3 1.0 SD B:MET278 4.4 46.5 1.0 C3 B:XG3602 4.5 59.3 1.0 HG3 C:PRO217 4.6 49.6 1.0 HA C:ASN213 4.7 55.5 1.0 C C:LEU212 4.7 54.3 1.0 HG12 C:ILE216 4.7 50.5 1.0 CG1 C:ILE216 4.8 50.5 1.0 N C:PRO217 4.8 49.6 1.0 CG C:PRO217 4.8 49.6 1.0 HG23 C:ILE216 4.8 50.5 1.0 CD1 C:ILE216 4.9 50.5 1.0 C2 B:XG3602 4.9 59.3 1.0

Fluorine binding site 6 out of 15 in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738 within 5.0Å range: probe atom residue distance (Å) B Occ B:F602 b:59.3 occ:1.00 F2 B:XG3602 0.0 59.3 1.0 C6 B:XG3602 1.3 59.3 1.0 F1 B:XG3602 2.1 59.3 1.0 F B:XG3602 2.1 59.3 1.0 C5 B:XG3602 2.4 59.3 1.0 H2 B:XG3602 2.4 59.3 1.0 C4 B:XG3602 2.7 59.3 1.0 O C:LEU212 3.4 54.3 1.0 C B:XG3602 3.6 59.3 1.0 HD22 C:LEU212 3.7 54.3 1.0 HD13 C:ILE216 3.8 50.5 1.0 HB3 C:LEU212 3.9 54.3 1.0 H B:XG3602 4.0 59.3 1.0 HB C:ILE216 4.1 50.5 1.0 HB2 B:ALA275 4.1 49.1 1.0 C3 B:XG3602 4.1 59.3 1.0 HE1 B:MET278 4.1 46.5 1.0 C C:LEU212 4.4 54.3 1.0 O B:XG3602 4.4 59.3 1.0 HG21 C:ILE216 4.4 50.5 1.0 HA C:LEU212 4.5 54.3 1.0 HG12 C:ILE216 4.6 50.5 1.0 HE2 B:MET278 4.6 46.5 1.0 HG22 C:ILE216 4.6 50.5 1.0 CD2 C:LEU212 4.7 54.3 1.0 CB C:LEU212 4.7 54.3 1.0 CD1 C:ILE216 4.7 50.5 1.0 CB C:ILE216 4.8 50.5 1.0 C1 B:XG3602 4.8 59.3 1.0 CA C:LEU212 4.8 54.3 1.0 HD13 C:LEU212 4.8 54.3 1.0 CE B:MET278 4.8 46.5 1.0 CG2 C:ILE216 4.8 50.5 1.0 HB1 B:ALA275 4.9 49.1 1.0 CB B:ALA275 4.9 49.1 1.0 CG1 C:ILE216 4.9 50.5 1.0 HD3 C:PRO217 4.9 49.6 1.0 C2 B:XG3602 4.9 59.3 1.0

Fluorine binding site 7 out of 15 in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738 within 5.0Å range: probe atom residue distance (Å) B Occ C:F602 b:59.6 occ:1.00 F C:XG3602 0.0 59.6 1.0 C6 C:XG3602 1.3 59.6 1.0 F1 C:XG3602 2.1 59.6 1.0 F2 C:XG3602 2.1 59.6 1.0 C5 C:XG3602 2.4 59.6 1.0 HE2 C:MET278 2.5 45.8 1.0 HE1 C:MET278 2.6 45.8 1.0 H C:XG3602 2.7 59.6 1.0 C C:XG3602 2.9 59.6 1.0 CE C:MET278 3.0 45.8 1.0 HB2 C:ALA275 3.2 48.8 1.0 HA C:ALA275 3.3 48.8 1.0 C4 C:XG3602 3.5 59.6 1.0 HE3 C:MET278 3.6 45.8 1.0 HB1 C:ALA275 3.7 48.8 1.0 H2 C:XG3602 3.8 59.6 1.0 CB C:ALA275 3.8 48.8 1.0 CA C:ALA275 4.0 48.8 1.0 C1 C:XG3602 4.2 59.6 1.0 HG22 D:ILE216 4.3 50.8 1.0 SD C:MET278 4.3 45.8 1.0 HG21 D:ILE216 4.4 50.8 1.0 HB3 C:MET278 4.4 45.8 1.0 C3 C:XG3602 4.7 59.6 1.0 HB3 C:ALA275 4.7 48.8 1.0 HB D:ILE216 4.7 50.8 1.0 CG2 D:ILE216 4.8 50.8 1.0 N C:ALA275 4.8 48.8 1.0 HD11 C:ILE279 4.9 43.6 1.0 H1 C:XG3602 4.9 59.6 1.0 HD3 D:PRO217 4.9 50.1 1.0 C2 C:XG3602 5.0 59.6 1.0

Fluorine binding site 8 out of 15 in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738 within 5.0Å range: probe atom residue distance (Å) B Occ C:F602 b:59.6 occ:1.00 F1 C:XG3602 0.0 59.6 1.0 C6 C:XG3602 1.3 59.6 1.0 F2 C:XG3602 2.1 59.6 1.0 F C:XG3602 2.1 59.6 1.0 C5 C:XG3602 2.4 59.6 1.0 HE1 C:MET278 2.5 45.8 1.0 HD3 D:PRO217 3.0 50.1 1.0 H C:XG3602 3.1 59.6 1.0 C C:XG3602 3.1 59.6 1.0 HB D:ILE216 3.2 50.8 1.0 C4 C:XG3602 3.3 59.6 1.0 HG22 D:ILE216 3.3 50.8 1.0 CE C:MET278 3.4 45.8 1.0 O D:LEU212 3.5 54.9 1.0 H2 C:XG3602 3.5 59.6 1.0 HE2 C:MET278 3.6 45.8 1.0 HD2 D:PRO217 3.6 50.1 1.0 CD D:PRO217 3.7 50.1 1.0 HG21 D:ILE216 3.9 50.8 1.0 CG2 D:ILE216 3.9 50.8 1.0 CB D:ILE216 4.0 50.8 1.0 HE3 C:MET278 4.0 45.8 1.0 HD13 D:ILE216 4.2 50.8 1.0 C1 C:XG3602 4.3 59.6 1.0 SD C:MET278 4.4 45.8 1.0 C3 C:XG3602 4.5 59.6 1.0 HG3 D:PRO217 4.6 50.1 1.0 HA D:ASN213 4.7 55.6 1.0 C D:LEU212 4.7 54.9 1.0 HG12 D:ILE216 4.7 50.8 1.0 CG1 D:ILE216 4.8 50.8 1.0 N D:PRO217 4.8 50.1 1.0 CG D:PRO217 4.8 50.1 1.0 HG23 D:ILE216 4.8 50.8 1.0 CD1 D:ILE216 4.9 50.8 1.0 C2 C:XG3602 4.9 59.6 1.0

Fluorine binding site 9 out of 15 in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738 within 5.0Å range: probe atom residue distance (Å) B Occ C:F602 b:59.6 occ:1.00 F2 C:XG3602 0.0 59.6 1.0 C6 C:XG3602 1.3 59.6 1.0 F1 C:XG3602 2.1 59.6 1.0 F C:XG3602 2.1 59.6 1.0 C5 C:XG3602 2.4 59.6 1.0 H2 C:XG3602 2.4 59.6 1.0 C4 C:XG3602 2.7 59.6 1.0 O D:LEU212 3.4 54.9 1.0 C C:XG3602 3.6 59.6 1.0 HD22 D:LEU212 3.7 54.9 1.0 HD13 D:ILE216 3.8 50.8 1.0 HB3 D:LEU212 3.9 54.9 1.0 H C:XG3602 4.0 59.6 1.0 HB D:ILE216 4.1 50.8 1.0 HB2 C:ALA275 4.1 48.8 1.0 C3 C:XG3602 4.1 59.6 1.0 HE1 C:MET278 4.1 45.8 1.0 C D:LEU212 4.4 54.9 1.0 O C:XG3602 4.4 59.6 1.0 HG21 D:ILE216 4.4 50.8 1.0 HA D:LEU212 4.5 54.9 1.0 HG12 D:ILE216 4.6 50.8 1.0 HE2 C:MET278 4.6 45.8 1.0 HG22 D:ILE216 4.6 50.8 1.0 CD2 D:LEU212 4.7 54.9 1.0 CB D:LEU212 4.7 54.9 1.0 CD1 D:ILE216 4.7 50.8 1.0 CB D:ILE216 4.8 50.8 1.0 C1 C:XG3602 4.8 59.6 1.0 CA D:LEU212 4.8 54.9 1.0 HD13 D:LEU212 4.8 54.9 1.0 CE C:MET278 4.8 45.8 1.0 CG2 D:ILE216 4.8 50.8 1.0 HB1 C:ALA275 4.9 48.8 1.0 CG1 D:ILE216 4.9 50.8 1.0 CB C:ALA275 4.9 48.8 1.0 HD3 D:PRO217 4.9 50.1 1.0 C2 C:XG3602 4.9 59.6 1.0

Fluorine binding site 10 out of 15 in the ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 10 of ALPHA7-Nicotinic Acetylcholine Receptor Bound to Epibatidine and Ns- 1738 within 5.0Å range: probe atom residue distance (Å) B Occ D:F602 b:60.7 occ:1.00 F D:XG3602 0.0 60.7 1.0 C6 D:XG3602 1.3 60.7 1.0 F1 D:XG3602 2.1 60.7 1.0 F2 D:XG3602 2.1 60.7 1.0 C5 D:XG3602 2.4 60.7 1.0 HE2 D:MET278 2.5 45.8 1.0 HE1 D:MET278 2.6 45.8 1.0 H D:XG3602 2.7 60.7 1.0 C D:XG3602 2.9 60.7 1.0 CE D:MET278 3.0 45.8 1.0 HB2 D:ALA275 3.2 48.1 1.0 HA D:ALA275 3.3 48.1 1.0 C4 D:XG3602 3.5 60.7 1.0 HE3 D:MET278 3.6 45.8 1.0 HB1 D:ALA275 3.7 48.1 1.0 H2 D:XG3602 3.8 60.7 1.0 CB D:ALA275 3.8 48.1 1.0 CA D:ALA275 4.0 48.1 1.0 C1 D:XG3602 4.2 60.7 1.0 HG22 E:ILE216 4.3 51.3 1.0 SD D:MET278 4.3 45.8 1.0 HG21 E:ILE216 4.4 51.3 1.0 HB3 D:MET278 4.4 45.8 1.0 C3 D:XG3602 4.7 60.7 1.0 HB3 D:ALA275 4.7 48.1 1.0 HB E:ILE216 4.7 51.3 1.0 CG2 E:ILE216 4.8 51.3 1.0 N D:ALA275 4.8 48.1 1.0 HD11 D:ILE279 4.9 43.4 1.0 H1 D:XG3602 4.9 60.7 1.0 HD3 E:PRO217 4.9 50.5 1.0 C2 D:XG3602 5.0 60.7 1.0

S.M.Burke, M.Avstrikova, C.M.Noviello, N.Mukhtasimova, J.P.Changeux, G.A.Thakur, S.M.Sine, M.Cecchini, R.E.Hibbs. Structural Mechanisms of ALPHA7 Nicotinic Receptor Allosteric Modulation and Activation To Be Published.