Fluorine in PDB 8v7c: Human Dna Polymerase Eta-Dna-Dt Primer Gemctp Insertion Ternary Complex at PH7.0 (K+ Mes) with 1 CA2+ Ion

All present enzymatic activity of Human Dna Polymerase Eta-Dna-Dt Primer Gemctp Insertion Ternary Complex at PH7.0 (K+ Mes) with 1 CA2+ Ion:
2.7.7.7;

The structure of Human Dna Polymerase Eta-Dna-Dt Primer Gemctp Insertion Ternary Complex at PH7.0 (K+ Mes) with 1 CA2+ Ion, PDB code: 8v7c was solved by C.Chang, Y.Gao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.81 / 1.79
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	98.854, 98.854, 82.122, 90, 90, 120
R / Rfree (%)	17.9 / 20.7

The structure of Human Dna Polymerase Eta-Dna-Dt Primer Gemctp Insertion Ternary Complex at PH7.0 (K+ Mes) with 1 CA2+ Ion also contains other interesting chemical elements:

Calcium	(Ca)	1 atom
Potassium	(K)	1 atom

The binding sites of Fluorine atom in the Human Dna Polymerase Eta-Dna-Dt Primer Gemctp Insertion Ternary Complex at PH7.0 (K+ Mes) with 1 CA2+ Ion (pdb code 8v7c). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Human Dna Polymerase Eta-Dna-Dt Primer Gemctp Insertion Ternary Complex at PH7.0 (K+ Mes) with 1 CA2+ Ion, PDB code: 8v7c:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in the Human Dna Polymerase Eta-Dna-Dt Primer Gemctp Insertion Ternary Complex at PH7.0 (K+ Mes) with 1 CA2+ Ion


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Human Dna Polymerase Eta-Dna-Dt Primer Gemctp Insertion Ternary Complex at PH7.0 (K+ Mes) with 1 CA2+ Ion within 5.0Å range: probe atom residue distance (Å) B Occ A:F504 b:33.9 occ:0.85 F1 A:GTF504 0.0 33.9 0.8 C2' A:GTF504 1.4 27.9 0.8 F2 A:GTF504 2.2 32.0 0.8 C3' A:GTF504 2.4 27.2 0.8 C1' A:GTF504 2.4 26.6 0.8 O3' A:GTF504 2.6 25.3 0.8 CD2 A:PHE18 2.9 22.0 1.0 CG A:PHE18 2.9 19.2 1.0 CE2 A:PHE18 3.2 25.1 1.0 C4' A:GTF504 3.2 24.9 0.8 CD1 A:PHE18 3.2 20.9 1.0 O4' A:GTF504 3.3 31.4 0.8 CZ A:PHE18 3.4 26.8 1.0 CE1 A:PHE18 3.4 24.2 1.0 N1 A:GTF504 3.5 30.9 0.8 CB A:PHE18 3.6 16.4 1.0 O2 A:GTF504 3.7 31.5 0.8 CB A:ALA49 3.9 17.7 1.0 C2 A:GTF504 4.0 32.4 0.8 O A:ILE48 4.1 27.5 1.0 O A:HOH615 4.3 46.0 1.0 CD1 A:ILE48 4.4 30.8 1.0 N A:PHE18 4.5 16.6 1.0 CG1 A:ILE48 4.5 24.1 1.0 C6 A:GTF504 4.5 31.2 0.8 C A:ILE48 4.5 23.9 1.0 C5' A:GTF504 4.6 31.3 0.8 CA A:PHE18 4.6 16.7 1.0 CB A:ILE48 4.7 27.8 1.0 CA A:ALA49 4.9 20.5 1.0 N A:ALA49 4.9 22.2 1.0

Fluorine binding site 2 out of 2 in the Human Dna Polymerase Eta-Dna-Dt Primer Gemctp Insertion Ternary Complex at PH7.0 (K+ Mes) with 1 CA2+ Ion


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Human Dna Polymerase Eta-Dna-Dt Primer Gemctp Insertion Ternary Complex at PH7.0 (K+ Mes) with 1 CA2+ Ion within 5.0Å range: probe atom residue distance (Å) B Occ A:F504 b:32.0 occ:0.85 F2 A:GTF504 0.0 32.0 0.8 C2' A:GTF504 1.4 27.9 0.8 F1 A:GTF504 2.2 33.9 0.8 O A:ILE48 2.4 27.5 1.0 C3' A:GTF504 2.4 27.2 0.8 C1' A:GTF504 2.4 26.6 0.8 N1 A:GTF504 2.6 30.9 0.8 NH2 A:ARG61 3.1 33.7 1.0 C2 A:GTF504 3.1 32.4 0.8 C6 A:GTF504 3.2 31.2 0.8 O3' A:GTF504 3.2 25.3 0.8 C A:ILE48 3.3 23.9 1.0 O2 A:GTF504 3.4 31.5 0.8 O4' A:GTF504 3.5 31.4 0.8 C4' A:GTF504 3.5 24.9 0.8 NE A:ARG61 3.6 34.0 1.0 CB A:ALA49 3.8 17.7 1.0 CZ A:ARG61 3.8 38.1 1.0 N3 A:GTF504 4.0 30.5 0.8 C5 A:GTF504 4.0 28.6 0.8 N A:ALA49 4.0 22.2 1.0 CA A:ALA49 4.0 20.5 1.0 CB A:ILE48 4.1 27.8 1.0 CA A:ILE48 4.2 20.8 1.0 C4 A:GTF504 4.4 31.4 0.8 O2B A:GTF504 4.4 26.2 0.8 CG1 A:ILE48 4.5 24.1 1.0 O5' A:GTF504 4.5 26.8 0.8 C5' A:GTF504 4.6 31.3 0.8 CD2 A:PHE18 4.9 22.0 1.0 CD A:ARG61 4.9 36.4 1.0 CD1 A:ILE48 4.9 30.8 1.0 O A:HOH647 5.0 23.8 1.0 CG A:PHE18 5.0 19.2 1.0

C.Chang, Y.Gao. Human Dna Polymerase Eta-Dna-Dt Primer Gemctp Insertion Ternary Complex at PH7.0 (K+ Mes) with 1 CA2+ Ion To Be Published.