Fluorine in PDB 8wfl: Human Glycine Transporter 1 in Complex with Pf-03463275 in Outward Facing Conformation

The structure of Human Glycine Transporter 1 in Complex with Pf-03463275 in Outward Facing Conformation also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Fluorine atom in the Human Glycine Transporter 1 in Complex with Pf-03463275 in Outward Facing Conformation (pdb code 8wfl). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Human Glycine Transporter 1 in Complex with Pf-03463275 in Outward Facing Conformation, PDB code: 8wfl:

Fluorine binding site 1 out of 1 in the Human Glycine Transporter 1 in Complex with Pf-03463275 in Outward Facing Conformation


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Human Glycine Transporter 1 in Complex with Pf-03463275 in Outward Facing Conformation within 5.0Å range: probe atom residue distance (Å) B Occ A:F701 b:82.5 occ:1.00 F02 A:W5X701 0.0 82.5 1.0 C25 A:W5X701 1.4 76.2 1.0 C23 A:W5X701 2.5 65.5 1.0 C22 A:W5X701 2.5 78.5 1.0 CL01 A:W5X701 3.3 98.2 1.0 CG2 A:VAL145 3.3 69.2 1.0 C20 A:W5X701 3.9 70.4 1.0 C19 A:W5X701 3.9 69.9 1.0 CD1 A:LEU470 3.9 76.3 1.0 CG A:LEU470 4.0 78.8 1.0 CD2 A:LEU470 4.0 77.5 1.0 CE2 A:TYR141 4.3 80.6 1.0 CD2 A:TYR141 4.4 74.7 1.0 C17 A:W5X701 4.4 69.7 1.0 CB A:VAL145 4.5 69.2 1.0 OD2 A:ASP474 4.6 81.4 1.0 CG A:ASP474 4.6 80.0 1.0 CG1 A:VAL145 4.6 70.1 1.0 CZ2 A:TRP70 4.7 69.7 1.0 CB A:ASP474 4.7 79.0 1.0 O A:TYR141 4.8 79.7 1.0 CD2 A:LEU471 4.9 70.5 1.0

Y.Wei, R.Li, Y.Meng, T.Hu, J.Zhao, Y.Gao, Q.Bai, N.Li, Y.Zhao. Transport Mechanism and Pharmacology of the Human GLYT1. Cell 2024.
ISSN: ISSN 1097-4172
PubMed: 38513663
DOI: 10.1016/J.CELL.2024.02.026