Fluorine in PDB 8x0b: Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465

The binding sites of Fluorine atom in the Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465 (pdb code 8x0b). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465, PDB code: 8x0b:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in the Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465 within 5.0Å range: probe atom residue distance (Å) B Occ A:F903 b:179.1 occ:1.00 F1 A:XQT903 0.0 179.1 1.0 C15 A:XQT903 1.4 161.2 1.0 C16 A:XQT903 2.3 152.9 1.0 C14 A:XQT903 2.4 150.7 1.0 OG A:SER654 2.5 128.9 1.0 O A:GLY624 2.5 164.9 1.0 CA A:GLY628 3.1 118.2 1.0 CA A:ILE625 3.2 135.1 1.0 N A:GLY628 3.3 125.6 1.0 C A:GLY624 3.3 154.8 1.0 O A:ILE625 3.4 150.5 1.0 C17 A:XQT903 3.6 140.6 1.0 C13 A:XQT903 3.6 142.8 1.0 C A:ILE625 3.6 145.6 1.0 N A:ILE625 3.7 142.5 1.0 CB A:SER654 3.9 129.3 1.0 CB A:ALA810 4.1 144.5 1.0 C18 A:XQT903 4.1 136.5 1.0 C A:GLY628 4.1 122.0 1.0 CB A:ILE625 4.4 133.3 1.0 N A:TYR629 4.4 133.4 1.0 CA A:GLY624 4.6 164.8 1.0 C A:LEU627 4.6 140.7 1.0 C A:SER654 4.6 144.1 1.0 O A:SER654 4.7 161.1 1.0 CG2 A:ILE625 4.7 125.0 1.0 CA A:SER654 4.7 139.1 1.0 N A:CYS626 4.8 164.5 1.0 CA A:ALA810 4.8 139.4 1.0 C12 A:XQT903 4.8 147.4 1.0 CG1 A:ILE625 4.8 147.1 1.0

Fluorine binding site 2 out of 2 in the Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465 within 5.0Å range: probe atom residue distance (Å) B Occ B:F903 b:164.1 occ:1.00 F1 B:XQT903 0.0 164.1 1.0 C15 B:XQT903 1.4 143.1 1.0 C16 B:XQT903 2.3 143.9 1.0 C14 B:XQT903 2.3 136.1 1.0 O B:GLY624 2.4 179.2 1.0 C B:GLY624 3.0 165.5 1.0 OG B:SER654 3.4 147.4 1.0 CA B:ILE625 3.4 150.2 1.0 N B:ILE625 3.4 149.9 1.0 C17 B:XQT903 3.6 144.8 1.0 C13 B:XQT903 3.6 140.8 1.0 CA B:GLY628 3.9 133.5 1.0 CD1 B:ILE625 3.9 161.9 1.0 N B:GLY628 4.0 137.7 1.0 CA B:GLY624 4.0 177.6 1.0 C18 B:XQT903 4.1 146.1 1.0 C B:ILE625 4.1 152.4 1.0 O B:ILE625 4.1 144.5 1.0 O B:SER654 4.2 162.5 1.0 CB B:SER658 4.3 144.1 1.0 C B:SER654 4.3 167.1 1.0 CA B:PRO655 4.4 158.7 1.0 N B:PRO655 4.5 167.8 1.0 CG1 B:ILE625 4.5 161.9 1.0 CB B:SER654 4.5 157.3 1.0 CB B:ILE625 4.6 161.1 1.0 OG B:SER658 4.6 143.0 1.0 C12 B:XQT903 4.8 138.7 1.0 CB B:ALA810 4.9 125.2 1.0

K.R.Vinothkumar, G.Lebon, G.Cannone. Conformational Diversity in Class C Gpcr Positive Allosteric Modulation To Be Published.