Fluorine in PDB 8x0c: Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465, Conformer 1

The binding sites of Fluorine atom in the Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465, Conformer 1 (pdb code 8x0c). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465, Conformer 1, PDB code: 8x0c:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in the Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465, Conformer 1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465, Conformer 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:F903 b:41.7 occ:1.00 F1 A:XQT903 0.0 41.7 1.0 C15 A:XQT903 1.4 41.7 1.0 OG A:SER654 2.2 41.5 1.0 C16 A:XQT903 2.3 41.7 1.0 C14 A:XQT903 2.4 41.7 1.0 O A:GLY624 2.4 41.9 1.0 O A:SER654 2.9 41.6 1.0 C A:GLY624 2.9 42.0 1.0 OG A:SER658 3.0 41.9 1.0 C A:SER654 3.2 41.5 1.0 CB A:SER654 3.4 41.5 1.0 N A:ILE625 3.4 41.9 1.0 CA A:ILE625 3.5 41.9 1.0 C17 A:XQT903 3.6 41.7 1.0 C13 A:XQT903 3.6 41.7 1.0 CA A:SER654 3.7 41.5 1.0 N A:PRO655 3.8 41.4 1.0 CA A:GLY624 3.8 42.1 1.0 N A:GLY628 4.0 41.7 1.0 CB A:SER658 4.1 41.9 1.0 C18 A:XQT903 4.1 41.7 1.0 CA A:GLY628 4.1 41.7 1.0 CA A:PRO655 4.2 41.4 1.0 C A:ILE625 4.3 41.9 1.0 O A:ILE625 4.5 41.9 1.0 CD A:PRO655 4.7 41.4 1.0 CB A:ILE625 4.7 41.9 1.0 C12 A:XQT903 4.8 41.6 1.0 CG1 A:ILE625 4.8 41.9 1.0 N A:SER658 4.9 41.9 1.0

Fluorine binding site 2 out of 2 in the Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465, Conformer 1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Human Fl Metabotropic Glutamate Receptor 5, MGLU5-5M with Quisqualate and VU0424465, Conformer 1 within 5.0Å range: probe atom residue distance (Å) B Occ B:F903 b:41.6 occ:1.00 F1 B:XQT903 0.0 41.6 1.0 C15 B:XQT903 1.4 41.5 1.0 C16 B:XQT903 2.3 41.5 1.0 C14 B:XQT903 2.3 41.5 1.0 O B:GLY624 2.5 41.9 1.0 OG B:SER654 2.9 41.5 1.0 C B:GLY624 3.0 42.0 1.0 CA B:ILE625 3.2 41.9 1.0 N B:ILE625 3.3 41.9 1.0 C17 B:XQT903 3.6 41.5 1.0 C13 B:XQT903 3.6 41.5 1.0 C B:ILE625 4.0 42.0 1.0 O B:ILE625 4.0 42.0 1.0 CA B:GLY624 4.0 42.0 1.0 C18 B:XQT903 4.1 41.4 1.0 CB B:SER658 4.1 41.9 1.0 O B:SER654 4.1 41.7 1.0 N B:GLY628 4.2 41.8 1.0 CB B:SER654 4.2 41.5 1.0 C B:SER654 4.2 41.6 1.0 CA B:GLY628 4.2 41.8 1.0 CG1 B:ILE625 4.3 41.8 1.0 CB B:ILE625 4.3 41.8 1.0 N B:PRO655 4.4 41.6 1.0 CA B:PRO655 4.5 41.6 1.0 OG B:SER658 4.6 41.9 1.0 CA B:SER654 4.7 41.6 1.0 C12 B:XQT903 4.8 41.4 1.0

K.R.Vinothkumar, G.Lebon, G.Cannone. Conformational Diversity in Class C Gpcr Positive Allosteric Modulation To Be Published.