Fluorine in PDB 8xox: The Crystal Structure of FAK2 From Biortus.

All present enzymatic activity of The Crystal Structure of FAK2 From Biortus.:
2.7.10.2;

The structure of The Crystal Structure of FAK2 From Biortus., PDB code: 8xox was solved by F.Wang, W.Cheng, Z.Lv, C.Ju, J.Wang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.38 / 1.90
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	37.797, 59.132, 67.295, 90, 95.03, 90
R / Rfree (%)	16.9 / 23

The binding sites of Fluorine atom in the The Crystal Structure of FAK2 From Biortus. (pdb code 8xox). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the The Crystal Structure of FAK2 From Biortus., PDB code: 8xox:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in the The Crystal Structure of FAK2 From Biortus.


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of The Crystal Structure of FAK2 From Biortus. within 5.0Å range: probe atom residue distance (Å) B Occ A:F701 b:23.5 occ:1.00 F29 A:YAM701 0.0 23.5 1.0 C8 A:YAM701 1.3 22.9 1.0 F28 A:YAM701 2.1 20.3 1.0 F27 A:YAM701 2.1 25.3 1.0 C6 A:YAM701 2.3 20.5 1.0 C7 A:YAM701 2.7 18.5 1.0 CB A:MET502 3.4 19.8 1.0 O A:GLU503 3.4 21.7 1.0 CB A:VAL487 3.6 17.7 1.0 C5 A:YAM701 3.6 20.9 1.0 CE A:MET502 3.7 23.3 1.0 CG1 A:VAL487 3.8 17.9 1.0 CG A:MET502 3.8 20.4 1.0 N2 A:YAM701 4.0 19.3 1.0 CE2 A:TYR505 4.0 18.4 1.0 CG2 A:VAL487 4.1 19.1 1.0 N10 A:YAM701 4.2 22.3 1.0 CD2 A:TYR505 4.3 19.0 1.0 C A:GLU503 4.6 19.0 1.0 SD A:MET502 4.7 20.8 1.0 CA A:MET502 4.7 18.4 1.0 N A:GLU503 4.7 15.8 1.0 N4 A:YAM701 4.7 19.2 1.0 CB A:ALA455 4.7 22.2 1.0 CA A:VAL487 4.8 18.1 1.0 C3 A:YAM701 4.8 18.9 1.0 O A:LYS488 4.8 19.8 1.0 C A:MET502 4.9 18.8 1.0 O A:HOH833 4.9 24.5 1.0

Fluorine binding site 2 out of 3 in the The Crystal Structure of FAK2 From Biortus.


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of The Crystal Structure of FAK2 From Biortus. within 5.0Å range: probe atom residue distance (Å) B Occ A:F701 b:20.3 occ:1.00 F28 A:YAM701 0.0 20.3 1.0 C8 A:YAM701 1.3 22.9 1.0 F27 A:YAM701 2.1 25.3 1.0 F29 A:YAM701 2.1 23.5 1.0 C6 A:YAM701 2.4 20.5 1.0 N10 A:YAM701 3.0 22.3 1.0 C5 A:YAM701 3.0 20.9 1.0 CG A:MET502 3.3 20.4 1.0 CB A:MET502 3.3 19.8 1.0 C7 A:YAM701 3.4 18.5 1.0 O A:HOH833 3.5 24.5 1.0 CB A:ALA455 3.9 22.2 1.0 CD A:LYS457 4.1 35.2 1.0 CE A:MET502 4.1 23.3 1.0 N4 A:YAM701 4.3 19.2 1.0 C12 A:YAM701 4.3 22.9 1.0 OD2 A:ASP567 4.5 44.9 1.0 SD A:MET502 4.5 20.8 1.0 N2 A:YAM701 4.6 19.3 1.0 CG A:LYS457 4.6 29.9 1.0 O A:GLU503 4.7 21.7 1.0 CA A:MET502 4.9 18.4 1.0 C3 A:YAM701 4.9 18.9 1.0 O A:ALA455 4.9 23.4 1.0

Fluorine binding site 3 out of 3 in the The Crystal Structure of FAK2 From Biortus.


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of The Crystal Structure of FAK2 From Biortus. within 5.0Å range: probe atom residue distance (Å) B Occ A:F701 b:25.3 occ:1.00 F27 A:YAM701 0.0 25.3 1.0 C8 A:YAM701 1.3 22.9 1.0 F28 A:YAM701 2.1 20.3 1.0 F29 A:YAM701 2.1 23.5 1.0 C6 A:YAM701 2.3 20.5 1.0 C5 A:YAM701 3.0 20.9 1.0 N10 A:YAM701 3.0 22.3 1.0 O A:HOH833 3.0 24.5 1.0 C7 A:YAM701 3.4 18.5 1.0 O A:HOH914 3.6 34.3 1.0 CG1 A:VAL487 3.8 17.9 1.0 CG2 A:VAL487 4.0 19.1 1.0 CB A:VAL487 4.0 17.7 1.0 OD2 A:ASP567 4.0 44.9 1.0 N4 A:YAM701 4.2 19.2 1.0 CD2 A:LEU556 4.3 23.2 1.0 C12 A:YAM701 4.4 22.9 1.0 C17 A:YAM701 4.4 23.9 1.0 CE A:MET502 4.4 23.3 1.0 N2 A:YAM701 4.6 19.3 1.0 CG A:LEU556 4.7 21.2 1.0 CG A:ASP567 4.7 35.5 1.0 CG A:MET502 4.8 20.4 1.0 C3 A:YAM701 4.8 18.9 1.0 CB A:MET502 4.9 19.8 1.0 C13 A:YAM701 4.9 22.1 1.0

F.Wang, W.Cheng, Z.Lv, C.Ju, J.Wang. The Crystal Structure of FAK2 From Biortus. To Be Published.