Experimental structures of coordination spheres of Fluorine (F) in bioorganic molecules from X-Ray and NMR experiments. Coordination spheres were calculated with 5.0 Angstroms radius around Fluorine atoms.
PDB files 951-1000 (2vew - 2wf7):- 2vew - Crystal Strucutre of Protein Tyrosine Phosphatase 1B in Complex With An Isothiazolidinone-Containing Inhibitor
- 2vex - Crystal Strucutre of Protein Tyrosine Phosphatase 1B in Complex With An Isothiazolidinone-Containing Inhibitor
- 2vey - Crystal Strucutre of Protein Tyrosine Phosphatase 1B in Complex With An Isothiazolidinone-Containing Inhibitor
- 2vfz - Crystal Structure of Alpha-1,3 Galactosyltransferase (R365K) in Complex With Udp-2F-Galactose
- 2vh0 - Structure and Property Based Design of Factor Xa Inhibitors: Biaryl Pyrrolidin-2-Ones Incorporating Basic Heterocyclic Motifs
- 2vh6 - Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones With Biaryl P4 Motifs
- 2vj7 - Human Bace-1 in Complex With 3-(Ethylamino)-N-((1S,2R)-2- Hydroxy-1-(Phenylmethyl)-3-(((3-(Trifluoromethyl)Phenyl) Methyl)Amino)Propyl)-5-(2-Oxo-1-Pyrrolidinyl)Benzamide
- 2vk7 - The Structure of Clostridium Perfringens Nani Sialidase and Its Catalytic Intermediates
- 2vkq - Crystal Structure of Human Cytosolic 5'-Nucleotidase III ( Cn-III, NT5C3) in Complex With Beryllium Trifluoride
- 2vnm - Human Bace-1 in Complex With 3-(1,1-Dioxidotetrahydro-2H-1, 2-Thiazin-2-Yl)-5-(Ethylamino)-N-((1S,2R)-2-Hydroxy-1-( Phenylmethyl)-3-(((3-(Trifluoromethyl)Phenyl)Methyl)Amino) Propyl)Benzamide
- 2vnn - Human Bace-1 in Complex With 7-Ethyl-N-((1S,2R)-2-Hydroxy-1- (Phenylmethyl)-3-(((3-(Trifluoromethyl)Phenyl)Methyl)Amino) Propyl)-1-Methyl-3,4-Dihydro-1H-(1,2,5)Thiadiazepino(3,4,5- Hi)Indole-9-Carboxamide 2,2-Dioxide
- 2vp6 - Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase
- 2vpp - Drosophila Melanogaster Deoxyribonucleoside Kinase Successfully Activates Gemcitabine in Transduced Cancer Cell Lines
- 2vqj - Structure of HDAC4 Catalytic Domain Bound to A Trifluoromethylketone Inhbitor
- 2vqo - Structure Of HDAC4 Catalytic Domain With A Gain-of-Function Muation Bound to A Trifluoromethylketone Inhbitor
- 2vqq - Structure of HDAC4 Catalytic Domain (A Double Cysteine-To- Alanine Mutant) Bound to A Trifluoromethylketone Inhbitor
- 2vr1 - Crystal Structure of Biotin Carboxylase From E. Coli in Complex With Atp Analog, ADPCF2P.
- 2vs2 - Neutron Diffraction Structure of Endothiapepsin in Complex With A Gem- Diol Inhibitor.
- 2vtd - Crystal Structure of Murd Ligase in Complex With D-Glu Containing Sulfonamide Inhibitor
- 2vtn - Identification of N-(4-Piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1H-Pyrazole-3-Carboxamide (AT7519), A Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-Ray Crystallography and Structure Based Drug Design.
- 2vto - Identification of N-(4-Piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1H-Pyrazole-3-Carboxamide (AT7519), A Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-Ray Crystallography and Structure Based Drug Design.
- 2vtp - Identification of N-(4-Piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1H-Pyrazole-3-Carboxamide (AT7519), A Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-Ray Crystallography and Structure Based Drug Design.
- 2vtq - Identification of N-(4-Piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1H-Pyrazole-3-Carboxamide (AT7519), A Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-Ray Crystallography and Structure Based Drug Design.
- 2vtt - Identification of N-(4-Piperidinyl)-4-(2,6- Dichlorobenzoylamino)-1H-Pyrazole-3-Carboxamide (AT7519), A Novel Cyclin Dependent Kinase Inhibitor Using Fragment- Based X-Ray Crystallography and Structure Based Drug Design.
- 2vui - Crystal Structure of the Hupr Receiver Domain in Inhibitory Phospho-State
- 2vvc - Aminopyrrolidine Factor Xa Inhibitor
- 2vvt - Glutamate Racemase (Muri) From E. Faecalis in Complex With A 9-Benzyl Purine Inhibitor
- 2vvu - Aminopyrrolidine Factor Xa Inhibitor
- 2vvv - Aminopyrrolidine-Related Triazole Factor Xa Inhibitor
- 2vwl - Aminopyrrolidine Factor Xa Inhibitor
- 2vwm - Aminopyrrolidine Factor Xa Inhibitor
- 2vwn - Aminopyrrolidine Factor Xa Inhibitor
- 2vwo - Aminopyrrolidine Factor Xa Inhibitor
- 2vz2 - Human Mao B in Complex With Mofegiline
- 2w0w - Crystal Structure of Glmu From Haemophilus Influenzae in Complex With Quinazoline Inhibitor 2
- 2w17 - CDK2 in Complex With the Imidazole Pyrimidine Amide, Compound (S)-8B
- 2w1c - Structure Determination of Aurora Kinase in Complex With Inhibitor
- 2w3i - Crystal Structure of Fxa in Complex With 4,4-Disubstituted Pyrrolidine-1,2-Dicarboxamide Inhibitor 2
- 2w3k - Crystal Structure of Fxa in Complex With 4,4-Disubstituted Pyrrolidine-1,2-Dicarboxamide Inhibitor 1
- 2w4o - Crystal Structure of Human CAMK4 in Complex With 4-Amino( Sulfamoyl-Phenylamino)-Triazole-Carbothioic Acid (2,6- Difluoro-Phenyl)-Amide)
- 2w5u - Flavodoxin From Helicobacter Pylori in Complex With the C3 Inhibitor
- 2wap - 3D-Crystal Structure of Humanized-Rat Fatty Acid Amide Hydrolase (Faah) Conjugated With the Drug-Like Urea Inhibitor Pf-3845
- 2wb4 - Activated Diguanylate Cyclase Pled in Complex With C-Di-Gmp
- 2wbk - Structure Of The Michaelis Complex Of Beta-Mannosidase, MAN2A, Provides Insight Into the Conformational Itinerary of Mannoside Hydrolysis
- 2weg - Thermodynamic Optimisation of Carbonic Anhydrase Fragment Inhibitors
- 2weo - Thermodynamic Optimisation of Carbonic Anhydrase Fragment Inhibitors
- 2wf0 - Human Bace-1 in Complex With 4-Ethyl-N-((1S,2R)-2-Hydroxy-1- (Phenylmethyl)-3-(((3-(Trifluoromethyl)Phenyl)Methyl)Amino) Propyl)-8-(2-Oxo-1-Pyrrolidinyl)-6-Quinolinecarboxamide
- 2wf5 - Structure of Beta-Phosphoglucomutase Inhibited With Glucose- 6-Phospahte and Trifluoromagnesate
- 2wf6 - Structure of Beta-Phosphoglucomutase Inhibited With Glucose- 6-Phospahte and Aluminium Tetrafluoride
- 2wf7 - Structure of Beta-Phosphoglucomutase Inhibited With Glucose- 6-Phosphonate and Aluminium Tetrafluoride
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| We would like to acknowledge that these pictures of PDB structures of Fluorine coordination spheres were produced with valuable advice from our colleagues from http://3dpdb.com. |