Fluorine in PDB 9f1u: Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 81-Degree Helical Twist

Enzymatic activity of Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 81-Degree Helical Twist

Other elements in 9f1u:

Fluorine Binding Sites:

Fluorine binding site 1 out of 4 in 9f1u

Fluorine Binding Sites List in 9f1u

Fluorine binding site 1 out of 4 in the Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 81-Degree Helical Twist


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 81-Degree Helical Twist within 5.0Å range: probe atom residue distance (Å) B Occ A:F1102 b:162.2 occ:1.00 F1 A:ALF1102 0.0 162.2 1.0 AL A:ALF1102 1.8 162.2 1.0 HH21 A:ARG824 2.1 154.0 1.0 O2B A:ADP1101 2.4 146.6 1.0 F4 A:ALF1102 2.5 162.2 1.0 F3 A:ALF1102 2.5 162.2 1.0 OD2 A:ASP797 2.6 142.8 1.0 NH2 A:ARG824 2.7 154.0 1.0 HH22 A:ARG824 2.9 154.0 1.0 HB2 A:ASP797 3.4 142.8 1.0 PB A:ADP1101 3.5 146.6 1.0 F2 A:ALF1102 3.6 162.2 1.0 CG A:ASP797 3.6 142.8 1.0 O3B A:ADP1101 3.7 146.6 1.0 CZ A:ARG824 3.9 154.0 1.0 HE A:ARG824 3.9 154.0 1.0 HB A:THR332 4.0 139.6 1.0 CB A:ASP797 4.0 142.8 1.0 HA A:ASP797 4.2 142.8 1.0 NE A:ARG824 4.3 154.0 1.0 O1B A:ADP1101 4.4 146.6 1.0 H A:GLY333 4.4 138.2 1.0 HG22 A:THR332 4.4 139.6 1.0 HA2 A:GLY795 4.5 132.2 1.0 CA A:ASP797 4.7 142.8 1.0 O3A A:ADP1101 4.7 146.6 1.0 HD3 A:LYS336 4.7 121.5 1.0 OD1 A:ASP797 4.7 142.8 1.0 CB A:THR332 4.8 139.6 1.0 HG21 A:THR332 4.8 139.6 1.0 HB3 A:ASP797 4.8 142.8 1.0 HA A:THR332 4.8 139.6 1.0 NH1 A:ARG824 4.9 154.0 1.0 CG2 A:THR332 4.9 139.6 1.0 HG2 A:ARG822 4.9 148.1 1.0 HH12 A:ARG824 4.9 154.0 1.0

Fluorine binding site 2 out of 4 in 9f1u

Fluorine Binding Sites List in 9f1u

Fluorine binding site 2 out of 4 in the Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 81-Degree Helical Twist


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 81-Degree Helical Twist within 5.0Å range: probe atom residue distance (Å) B Occ A:F1102 b:162.2 occ:1.00 F2 A:ALF1102 0.0 162.2 1.0 AL A:ALF1102 1.8 162.2 1.0 F4 A:ALF1102 2.5 162.2 1.0 F3 A:ALF1102 2.6 162.2 1.0 HD3 A:LYS336 2.8 121.5 1.0 O1B A:ADP1101 2.9 146.6 1.0 HG3 A:LYS336 3.1 121.5 1.0 HG23 A:THR337 3.3 119.0 1.0 PB A:ADP1101 3.3 146.6 1.0 O3B A:ADP1101 3.4 146.6 1.0 HE2 A:LYS336 3.5 121.5 1.0 CD A:LYS336 3.5 121.5 1.0 O2B A:ADP1101 3.6 146.6 1.0 F1 A:ALF1102 3.6 162.2 1.0 CG A:LYS336 3.6 121.5 1.0 HG2 A:LYS336 3.8 121.5 1.0 CE A:LYS336 4.0 121.5 1.0 CG2 A:THR337 4.0 119.0 1.0 HZ2 A:LYS336 4.0 121.5 1.0 HG21 A:THR337 4.1 119.0 1.0 HG22 A:THR337 4.1 119.0 1.0 OD1 A:ASP444 4.3 90.8 1.0 HD2 A:LYS336 4.4 121.5 1.0 NZ A:LYS336 4.5 121.5 1.0 H A:THR337 4.8 119.0 1.0 HE3 A:LYS336 4.8 121.5 1.0 O3A A:ADP1101 4.9 146.6 1.0 OD2 A:ASP797 5.0 142.8 1.0 HZ3 A:LYS336 5.0 121.5 1.0

Fluorine binding site 3 out of 4 in 9f1u

Fluorine Binding Sites List in 9f1u

Fluorine binding site 3 out of 4 in the Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 81-Degree Helical Twist


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 81-Degree Helical Twist within 5.0Å range: probe atom residue distance (Å) B Occ A:F1102 b:162.2 occ:1.00 F3 A:ALF1102 0.0 162.2 1.0 AL A:ALF1102 1.8 162.2 1.0 HD3 A:LYS336 2.4 121.5 1.0 F1 A:ALF1102 2.5 162.2 1.0 O2B A:ADP1101 2.5 146.6 1.0 F2 A:ALF1102 2.6 162.2 1.0 HZ2 A:LYS336 2.9 121.5 1.0 HA A:THR332 3.2 139.6 1.0 O1B A:ADP1101 3.3 146.6 1.0 CD A:LYS336 3.3 121.5 1.0 PB A:ADP1101 3.3 146.6 1.0 HG22 A:THR332 3.4 139.6 1.0 H A:GLY333 3.4 138.2 1.0 F4 A:ALF1102 3.6 162.2 1.0 NZ A:LYS336 3.7 121.5 1.0 HB A:THR332 3.7 139.6 1.0 HD2 A:LYS336 3.7 121.5 1.0 CE A:LYS336 3.8 121.5 1.0 HE2 A:LYS336 3.9 121.5 1.0 HH21 A:ARG824 3.9 154.0 1.0 CA A:THR332 4.0 139.6 1.0 HZ1 A:LYS336 4.0 121.5 1.0 CB A:THR332 4.1 139.6 1.0 CG2 A:THR332 4.2 139.6 1.0 O3B A:ADP1101 4.2 146.6 1.0 N A:GLY333 4.2 138.2 1.0 HG3 A:LYS336 4.2 121.5 1.0 CG A:LYS336 4.2 121.5 1.0 HZ3 A:LYS336 4.3 121.5 1.0 HG2 A:LYS336 4.3 121.5 1.0 OD2 A:ASP797 4.5 142.8 1.0 HG21 A:THR332 4.5 139.6 1.0 O3A A:ADP1101 4.7 146.6 1.0 C A:THR332 4.7 139.6 1.0 NH2 A:ARG824 4.8 154.0 1.0 HE3 A:LYS336 4.8 121.5 1.0 HE A:ARG824 4.8 154.0 1.0 HG23 A:THR332 4.9 139.6 1.0 HB2 A:ALA490 4.9 122.3 1.0

Fluorine binding site 4 out of 4 in 9f1u

Fluorine Binding Sites List in 9f1u

Fluorine binding site 4 out of 4 in the Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 81-Degree Helical Twist


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 81-Degree Helical Twist within 5.0Å range: probe atom residue distance (Å) B Occ A:F1102 b:162.2 occ:1.00 F4 A:ALF1102 0.0 162.2 1.0 AL A:ALF1102 1.8 162.2 1.0 F1 A:ALF1102 2.5 162.2 1.0 F2 A:ALF1102 2.5 162.2 1.0 O3B A:ADP1101 2.8 146.6 1.0 HB2 A:ASP797 2.8 142.8 1.0 OD2 A:ASP797 3.3 142.8 1.0 O2B A:ADP1101 3.4 146.6 1.0 PB A:ADP1101 3.5 146.6 1.0 F3 A:ALF1102 3.6 162.2 1.0 CB A:ASP797 3.6 142.8 1.0 CG A:ASP797 3.8 142.8 1.0 HB3 A:ASP797 4.0 142.8 1.0 O1B A:ADP1101 4.1 146.6 1.0 HA2 A:GLY795 4.2 132.2 1.0 OE1 A:GLN372 4.4 115.0 1.0 HD13 A:LEU369 4.4 109.5 1.0 HH21 A:ARG824 4.4 154.0 1.0 H A:ASP797 4.6 142.8 1.0 HG21 A:THR337 4.6 119.0 1.0 HG23 A:THR337 4.6 119.0 1.0 CA A:ASP797 4.7 142.8 1.0 HH22 A:ARG824 4.8 154.0 1.0 HD22 A:LEU369 4.8 109.5 1.0 HA A:ASP797 4.8 142.8 1.0 NH2 A:ARG824 4.8 154.0 1.0 OD1 A:ASP797 4.9 142.8 1.0 O3A A:ADP1101 4.9 146.6 1.0

Reference: