Fluorine in PDB 9mel: Structure of the Human Twik-2 Potassium Channel in Complex with Pimozide

The structure of Structure of the Human Twik-2 Potassium Channel in Complex with Pimozide also contains other interesting chemical elements:

Potassium

(K)

3 atoms

The binding sites of Fluorine atom in the Structure of the Human Twik-2 Potassium Channel in Complex with Pimozide (pdb code 9mel). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Structure of the Human Twik-2 Potassium Channel in Complex with Pimozide, PDB code: 9mel:
Jump to Fluorine binding site number: 1; 2; 3; 4;

Fluorine binding site 1 out of 4 in the Structure of the Human Twik-2 Potassium Channel in Complex with Pimozide


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of the Human Twik-2 Potassium Channel in Complex with Pimozide within 5.0Å range: probe atom residue distance (Å) B Occ B:F401 b:46.2 occ:0.50 F01 B:1II401 0.0 46.2 0.5 C33 B:1II401 1.4 44.8 0.5 C19 B:1II401 2.3 43.8 0.5 C23 B:1II401 2.3 45.5 0.5 C31 B:1II401 2.3 42.8 0.5 C29 B:1II401 2.4 46.0 0.5 CG2 B:VAL250 3.0 41.2 1.0 CD2 B:LEU246 3.4 42.6 1.0 CD1 B:LEU138 3.5 36.9 1.0 C27 B:1II401 3.6 43.1 0.5 C25 B:1II401 3.6 46.6 0.5 C24 B:1II401 3.6 46.2 0.5 C14 B:1II401 3.6 44.4 0.5 O B:LEU246 3.9 37.2 1.0 C20 B:1II401 4.1 45.6 0.5 CB B:VAL250 4.4 42.9 1.0 CB B:LEU246 4.5 27.5 1.0 CG B:LEU246 4.6 36.3 1.0 N05 B:1II401 4.6 45.2 0.5 C18 B:1II401 4.6 45.2 0.5 C09 B:1II401 4.6 41.0 0.5 C B:LEU246 4.6 33.5 1.0 C22 B:1II401 4.6 46.1 0.5 C07 B:1II401 4.7 43.8 0.5 N B:VAL250 4.8 42.9 1.0 CA B:LEU246 4.8 28.6 1.0 CG B:LEU138 4.8 37.0 1.0 CA B:VAL250 4.9 42.2 1.0 CB B:LEU138 4.9 32.7 1.0 C10 B:1II401 5.0 44.0 0.5 CG2 B:THR214 5.0 31.9 1.0

Fluorine binding site 2 out of 4 in the Structure of the Human Twik-2 Potassium Channel in Complex with Pimozide


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Structure of the Human Twik-2 Potassium Channel in Complex with Pimozide within 5.0Å range: probe atom residue distance (Å) B Occ B:F401 b:46.2 occ:0.50 F01 B:1II401 0.0 46.2 0.5 C33 B:1II401 1.4 44.7 0.5 C19 B:1II401 2.2 43.9 0.5 C31 B:1II401 2.3 43.0 0.5 C29 B:1II401 2.4 45.5 0.5 C23 B:1II401 2.4 45.2 0.5 CG2 A:VAL250 3.0 41.2 1.0 CD1 A:LEU138 3.5 36.1 1.0 C14 B:1II401 3.5 44.3 0.5 C27 B:1II401 3.6 43.0 0.5 C25 B:1II401 3.6 46.3 0.5 C24 B:1II401 3.8 45.8 0.5 CD2 A:LEU246 3.8 42.8 1.0 C20 B:1II401 4.1 45.6 0.5 O A:LEU246 4.2 36.3 1.0 N05 B:1II401 4.4 44.7 0.5 CB A:VAL250 4.4 42.5 1.0 C07 B:1II401 4.5 43.1 0.5 C18 B:1II401 4.6 45.2 0.5 SD A:MET135 4.7 51.7 0.5 C22 B:1II401 4.7 46.0 0.5 CG A:LEU138 4.8 36.6 1.0 C09 B:1II401 4.8 41.4 0.5 CB A:LEU246 4.8 26.9 1.0 CB A:LEU138 4.8 32.0 1.0 N A:VAL250 4.9 42.6 1.0 C10 B:1II401 4.9 43.4 0.5 CA A:VAL250 4.9 42.1 1.0 C A:LEU246 5.0 32.9 1.0 CG A:LEU246 5.0 36.2 1.0

Fluorine binding site 3 out of 4 in the Structure of the Human Twik-2 Potassium Channel in Complex with Pimozide


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Structure of the Human Twik-2 Potassium Channel in Complex with Pimozide within 5.0Å range: probe atom residue distance (Å) B Occ B:F401 b:53.6 occ:0.50 F02 B:1II401 0.0 53.6 0.5 C34 B:1II401 1.4 48.1 0.5 C32 B:1II401 2.3 44.0 0.5 C30 B:1II401 2.3 48.9 0.5 C28 B:1II401 3.6 43.8 0.5 C26 B:1II401 3.6 46.4 0.5 C21 B:1II401 4.1 45.1 0.5 CG A:PRO132 4.3 53.8 1.0 CD1 A:LEU128 4.5 56.3 1.0 CD2 B:LEU253 4.7 46.9 1.0 CD A:PRO132 4.9 47.5 1.0 O A:LEU128 4.9 55.2 1.0

Fluorine binding site 4 out of 4 in the Structure of the Human Twik-2 Potassium Channel in Complex with Pimozide


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Structure of the Human Twik-2 Potassium Channel in Complex with Pimozide within 5.0Å range: probe atom residue distance (Å) B Occ B:F401 b:52.7 occ:0.50 F02 B:1II401 0.0 52.7 0.5 C34 B:1II401 1.4 47.6 0.5 C32 B:1II401 2.3 43.2 0.5 C30 B:1II401 2.3 48.8 0.5 C28 B:1II401 3.6 43.4 0.5 C26 B:1II401 3.6 45.6 0.5 C21 B:1II401 4.1 45.1 0.5 CG B:PRO132 4.2 54.3 1.0 CD2 A:LEU253 4.6 46.2 1.0 CD1 B:LEU128 4.6 56.5 1.0 CD B:PRO132 4.8 47.6 1.0 O B:LEU128 5.0 54.8 1.0

N.K.Khanra, C.Wang, B.Delgado, S.B.Long. Structure of Human TWIK2 Bound to Pimozide To Be Published.