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Fluorine in PDB 1a5s: Crystal Structure of Wild-Type Tryptophan Synthase Complexed with 5- Fluoroindole Propanol Phosphate and L-Ser Bound As Amino Acrylate to the Beta Site
Enzymatic activity of Crystal Structure of Wild-Type Tryptophan Synthase Complexed with 5- Fluoroindole Propanol Phosphate and L-Ser Bound As Amino Acrylate to the Beta Site
All present enzymatic activity of Crystal Structure of Wild-Type Tryptophan Synthase Complexed with 5- Fluoroindole Propanol Phosphate and L-Ser Bound As Amino Acrylate to the Beta Site:
4.2.1.20;
4.2.1.20;
Protein crystallography data
The structure of Crystal Structure of Wild-Type Tryptophan Synthase Complexed with 5- Fluoroindole Propanol Phosphate and L-Ser Bound As Amino Acrylate to the Beta Site, PDB code: 1a5s
was solved by
T.R.Schneider,
E.Gerhardt,
M.Lee,
P.-H.Liang,
K.S.Anderson,
I.Schlichting,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 10.00 / 2.30 |
| Space group | C 1 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 182.700, 60.800, 67.500, 90.00, 94.60, 90.00 |
| R / Rfree (%) | 17.7 / 24.7 |
Other elements in 1a5s:
The structure of Crystal Structure of Wild-Type Tryptophan Synthase Complexed with 5- Fluoroindole Propanol Phosphate and L-Ser Bound As Amino Acrylate to the Beta Site also contains other interesting chemical elements:
| Sodium | (Na) | 1 atom |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Wild-Type Tryptophan Synthase Complexed with 5- Fluoroindole Propanol Phosphate and L-Ser Bound As Amino Acrylate to the Beta Site
(pdb code 1a5s). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of Wild-Type Tryptophan Synthase Complexed with 5- Fluoroindole Propanol Phosphate and L-Ser Bound As Amino Acrylate to the Beta Site, PDB code: 1a5s:
In total only one binding site of Fluorine was determined in the Crystal Structure of Wild-Type Tryptophan Synthase Complexed with 5- Fluoroindole Propanol Phosphate and L-Ser Bound As Amino Acrylate to the Beta Site, PDB code: 1a5s:
Fluorine binding site 1 out of 1 in 1a5s
Go back to
Fluorine Binding Sites List in 1a5s
Fluorine binding site 1 out
of 1 in the Crystal Structure of Wild-Type Tryptophan Synthase Complexed with 5- Fluoroindole Propanol Phosphate and L-Ser Bound As Amino Acrylate to the Beta Site
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Crystal Structure of Wild-Type Tryptophan Synthase Complexed with 5- Fluoroindole Propanol Phosphate and L-Ser Bound As Amino Acrylate to the Beta Site within 5.0Å range:
|
Reference:
T.R.Schneider,
E.Gerhardt,
M.Lee,
P.H.Liang,
K.S.Anderson,
I.Schlichting.
Loop Closure and Intersubunit Communication in Tryptophan Synthase. Biochemistry V. 37 5394 1998.
ISSN: ISSN 0006-2960
PubMed: 9548921
DOI: 10.1021/BI9728957
Page generated: Mon Jul 14 10:18:12 2025
ISSN: ISSN 0006-2960
PubMed: 9548921
DOI: 10.1021/BI9728957
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