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Fluorine in PDB 1gj8: Engineering Inhibitors Highly Selective For the S1 Sites of SER190 Trypsin-Like Serine Protease Drug Targets
Enzymatic activity of Engineering Inhibitors Highly Selective For the S1 Sites of SER190 Trypsin-Like Serine Protease Drug Targets
All present enzymatic activity of Engineering Inhibitors Highly Selective For the S1 Sites of SER190 Trypsin-Like Serine Protease Drug Targets:
3.4.21.73;
3.4.21.73;
Protein crystallography data
The structure of Engineering Inhibitors Highly Selective For the S1 Sites of SER190 Trypsin-Like Serine Protease Drug Targets, PDB code: 1gj8
was solved by
B.A.Katz,
P.A.Sprengeler,
C.Luong,
E.Verner,
J.R.Spencer,
J.G.Breitenbucher,
H.Hui,
D.Mcgee,
D.Allen,
A.Martelli,
R.L.Mackman,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 7.00 / 1.64 |
| Space group | C 1 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 81.770, 50.020, 66.940, 90.00, 113.76, 90.00 |
| R / Rfree (%) | 18.8 / 22.1 |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Engineering Inhibitors Highly Selective For the S1 Sites of SER190 Trypsin-Like Serine Protease Drug Targets
(pdb code 1gj8). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Engineering Inhibitors Highly Selective For the S1 Sites of SER190 Trypsin-Like Serine Protease Drug Targets, PDB code: 1gj8:
In total only one binding site of Fluorine was determined in the Engineering Inhibitors Highly Selective For the S1 Sites of SER190 Trypsin-Like Serine Protease Drug Targets, PDB code: 1gj8:
Fluorine binding site 1 out of 1 in 1gj8
Go back to
Fluorine Binding Sites List in 1gj8
Fluorine binding site 1 out
of 1 in the Engineering Inhibitors Highly Selective For the S1 Sites of SER190 Trypsin-Like Serine Protease Drug Targets
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Engineering Inhibitors Highly Selective For the S1 Sites of SER190 Trypsin-Like Serine Protease Drug Targets within 5.0Å range:
|
Reference:
B.A.Katz,
P.A.Sprengeler,
C.Luong,
E.Verner,
K.Elrod,
M.Kirtley,
J.Janc,
J.R.Spencer,
J.G.Breitenbucher,
H.Hui,
D.Mcgee,
D.Allen,
A.Martelli,
R.L.Mackman.
Engineering Inhibitors Highly Selective For the S1 Sites of SER190 Trypsin-Like Serine Protease Drug Targets. Chem.Biol. V. 8 1107 2001.
ISSN: ISSN 1074-5521
PubMed: 11731301
DOI: 10.1016/S1074-5521(01)00084-9
Page generated: Mon Jul 14 10:49:20 2025
ISSN: ISSN 1074-5521
PubMed: 11731301
DOI: 10.1016/S1074-5521(01)00084-9
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