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Atomistry » Fluorine » PDB 1rw8-1uda » 1tkx » |
Fluorine in PDB 1tkx: Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with GW490745Enzymatic activity of Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with GW490745
All present enzymatic activity of Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with GW490745:
2.7.7.49; Protein crystallography data
The structure of Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with GW490745, PDB code: 1tkx
was solved by
J.Ren,
A.L.Hopkins,
D.I.Stuart,
D.K.Stammers,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with GW490745
(pdb code 1tkx). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with GW490745, PDB code: 1tkx: Fluorine binding site 1 out of 1 in 1tkxGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with GW490745
![]() Mono view ![]() Stereo pair view
Reference:
G.A.Freeman,
C.W.Andrews Iii,
A.L.Hopkins,
G.S.Lowell,
L.T.Schaller,
J.R.Cowan,
S.S.Gonzales,
G.W.Koszalka,
R.J.Hazen,
L.R.Boone,
R.G.Ferris,
K.L.Creech,
G.B.Roberts,
S.A.Short,
K.Weaver,
D.J.Reynolds,
J.Milton,
J.Ren,
D.I.Stuart,
D.K.Stammers,
J.H.Chan.
Design of Non-Nucleoside Inhibitors of Hiv-1 Reverse Transcriptase with Improved Drug Resistance Properties. 2. J.Med.Chem. V. 47 5923 2004.
Page generated: Wed Jul 31 12:57:38 2024
ISSN: ISSN 0022-2623 PubMed: 15537347 DOI: 10.1021/JM040072R |
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