Fluorine in PDB 1ysg: Solution Structure of the Anti-Apoptotic Protein Bcl-Xl in Complex with "Sar By uc(Nmr)" Ligands

The binding sites of Fluorine atom in the Solution Structure of the Anti-Apoptotic Protein Bcl-Xl in Complex with "Sar By uc(Nmr)" Ligands (pdb code 1ysg). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Solution Structure of the Anti-Apoptotic Protein Bcl-Xl in Complex with "Sar By uc(Nmr)" Ligands, PDB code: 1ysg:

Fluorine binding site 1 out of 1 in the Solution Structure of the Anti-Apoptotic Protein Bcl-Xl in Complex with "Sar By uc(Nmr)" Ligands


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Solution Structure of the Anti-Apoptotic Protein Bcl-Xl in Complex with "Sar By uc(Nmr)" Ligands within 5.0Å range: probe atom residue distance (Å) B Occ A:F1000 b:0.4 occ:1.00 F1 A:4FC1000 0.0 0.4 1.0 C2 A:4FC1000 1.3 0.3 1.0 C1 A:4FC1000 2.4 1.2 1.0 C3 A:4FC1000 2.4 1.3 1.0 HA2 A:4FC1000 2.6 2.2 1.0 HA1 A:4FC1000 2.6 2.1 1.0 HD23 A:LEU112 2.7 1.4 1.0 CD2 A:PHE109 2.9 1.1 1.0 HA A:PHE109 2.9 0.6 1.0 CG A:PHE109 3.0 0.6 1.0 HD2 A:PHE109 3.1 1.9 1.0 HB1 A:ALA108 3.1 0.9 1.0 HD13 A:LEU112 3.2 1.1 1.0 CE2 A:PHE109 3.3 1.3 1.0 O A:ALA108 3.4 1.2 1.0 CA A:PHE109 3.5 0.7 1.0 C A:ALA108 3.5 0.5 1.0 N A:PHE109 3.5 0.7 1.0 CD1 A:PHE109 3.6 1.5 1.0 CB A:PHE109 3.6 0.8 1.0 HB2 A:PHE109 3.6 1.0 1.0 HB3 A:TYR105 3.6 0.8 1.0 C6 A:4FC1000 3.6 1.1 1.0 C4 A:4FC1000 3.6 1.3 1.0 HE2 A:PHE109 3.8 2.2 1.0 CZ A:PHE109 3.8 0.6 1.0 CD2 A:LEU112 3.8 0.7 1.0 CE1 A:PHE109 3.9 1.3 1.0 CB A:ALA108 4.0 0.7 1.0 HB3 A:ALA108 4.0 1.3 1.0 HD13 A:LEU134 4.1 1.9 1.0 H A:PHE109 4.1 1.2 1.0 C5 A:4FC1000 4.1 0.3 1.0 CD1 A:LEU112 4.1 0.5 1.0 HD1 A:PHE109 4.2 2.4 1.0 HD22 A:LEU112 4.2 1.0 1.0 HB2 A:TYR105 4.3 0.8 1.0 HD21 A:LEU112 4.3 1.1 1.0 CA A:ALA108 4.4 0.5 1.0 HB2 A:LEU112 4.4 0.8 1.0 CB A:TYR105 4.4 0.8 1.0 HD11 A:LEU112 4.4 0.9 1.0 HB2 A:4FC1000 4.5 2.0 1.0 HB1 A:4FC1000 4.5 2.2 1.0 CG A:LEU112 4.5 0.5 1.0 HZ A:PHE109 4.5 0.7 1.0 HB3 A:PHE109 4.6 1.1 1.0 HD22 A:LEU134 4.6 1.9 1.0 O A:TYR105 4.6 1.0 1.0 HE1 A:PHE109 4.7 2.2 1.0 HB3 A:ALA146 4.7 0.9 1.0 HD21 A:LEU134 4.9 1.7 1.0 HB2 A:ALA108 4.9 1.4 1.0 HD12 A:LEU112 4.9 1.3 1.0 C A:PHE109 4.9 0.8 1.0 CB A:LEU112 5.0 0.8 1.0

T.Oltersdorf, S.W.Elmore, A.R.Shoemaker, R.C.Armstrong, D.J.Augeri, B.A.Belli, M.Bruncko, T.L.Deckwerth, J.Dinges, P.J.Hajduk, M.K.Joseph, S.Kitada, S.J.Korsmeyer, A.R.Kunzer, A.Letai, C.Li, M.J.Mitten, D.G.Nettesheim, S.Ng, P.M.Nimmer, J.M.O'connor, A.Oleksijew, A.M.Petros, J.C.Reed, W.Shen, S.K.Tahir, C.B.Thompson, K.J.Tomaselli, B.Wang, M.D.Wendt, H.Zhang, S.W.Fesik, S.H.Rosenberg. An Inhibitor of Bcl-2 Family Proteins Induces Regression of Solid Tumours Nature V. 435 677 2005.
ISSN: ISSN 0028-0836
PubMed: 15902208
DOI: 10.1038/NATURE03579