Atomistry » Fluorine » PDB 1xz3-1zzr » 1ysi
Atomistry »
  Fluorine »
    PDB 1xz3-1zzr »
      1ysi »

Fluorine in PDB 1ysi: Solution Structure of the Anti-Apoptotic Protein Bcl-Xl in Complex with An Acyl-Sulfonamide-Based Ligand

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Solution Structure of the Anti-Apoptotic Protein Bcl-Xl in Complex with An Acyl-Sulfonamide-Based Ligand (pdb code 1ysi). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Solution Structure of the Anti-Apoptotic Protein Bcl-Xl in Complex with An Acyl-Sulfonamide-Based Ligand, PDB code: 1ysi:

Fluorine binding site 1 out of 1 in 1ysi

Go back to Fluorine Binding Sites List in 1ysi
Fluorine binding site 1 out of 1 in the Solution Structure of the Anti-Apoptotic Protein Bcl-Xl in Complex with An Acyl-Sulfonamide-Based Ligand


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Solution Structure of the Anti-Apoptotic Protein Bcl-Xl in Complex with An Acyl-Sulfonamide-Based Ligand within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1000

b:1.0
occ:1.00
F7 A:N3B1000 0.0 1.0 1.0
C2 A:N3B1000 1.3 0.9 1.0
C1 A:N3B1000 2.4 1.5 1.0
C3 A:N3B1000 2.4 1.4 1.0
HA1 A:N3B1000 2.6 2.4 1.0
O A:ALA108 2.6 2.4 1.0
HA2 A:N3B1000 2.6 2.3 1.0
HD13 A:LEU112 2.9 1.2 1.0
HD21 A:LEU134 2.9 0.8 1.0
HD1 A:PHE109 3.0 2.2 1.0
HA A:PHE109 3.3 0.7 1.0
C A:ALA108 3.4 1.7 1.0
C4 A:N3B1000 3.6 1.4 1.0
C6 A:N3B1000 3.6 1.4 1.0
HB3 A:PHE109 3.8 1.9 1.0
HG A:LEU112 3.9 0.4 1.0
CD2 A:LEU134 3.9 0.3 1.0
CD1 A:LEU112 4.0 0.6 1.0
CA A:PHE109 4.0 0.8 1.0
CD1 A:PHE109 4.0 1.6 1.0
N A:PHE109 4.0 0.9 1.0
C5 A:N3B1000 4.1 0.7 1.0
HD22 A:LEU134 4.1 0.9 1.0
HA A:ALA108 4.1 2.5 1.0
HB2 A:ALA108 4.2 3.4 1.0
HD23 A:LEU134 4.3 1.0 1.0
CA A:ALA108 4.3 2.1 1.0
CB A:PHE109 4.4 1.3 1.0
CG A:LEU112 4.5 0.3 1.0
HB1 A:N3B1000 4.5 2.2 1.0
HB2 A:N3B1000 4.5 2.3 1.0
HD11 A:LEU112 4.5 1.3 1.0
HD12 A:LEU112 4.6 1.0 1.0
HD21 A:LEU112 4.6 1.3 1.0
CG A:PHE109 4.7 0.9 1.0
CB A:ALA108 4.8 2.7 1.0
HG A:LEU134 4.9 0.2 1.0
H A:PHE109 4.9 1.1 1.0
HE1 A:PHE109 5.0 3.0 1.0

Reference:

T.Oltersdorf, S.W.Elmore, A.R.Shoemaker, R.C.Armstrong, D.J.Augeri, B.A.Belli, M.Bruncko, T.L.Deckwerth, J.Dinges, P.J.Hajduk, M.K.Joseph, S.Kitada, S.J.Korsmeyer, A.R.Kunzer, A.Letai, C.Li, M.J.Mitten, D.G.Nettesheim, S.Ng, P.M.Nimmer, J.M.O'connor, A.Oleksijew, A.M.Petros, J.C.Reed, W.Shen, S.K.Tahir, C.B.Thompson, K.J.Tomaselli, B.Wang, M.D.Wendt, H.Zhang, S.W.Fesik, S.H.Rosenberg. An Inhibitor of Bcl-2 Family Proteins Induces Regression of Solid Tumours Nature V. 435 677 2005.
ISSN: ISSN 0028-0836
PubMed: 15902208
DOI: 10.1038/NATURE03579
Page generated: Wed Jul 31 13:34:20 2024

Last articles

Cl in 4HNL
Cl in 4HOD
Cl in 4HNI
Cl in 4HNV
Cl in 4HN0
Cl in 4HNF
Cl in 4HNG
Cl in 4HNH
Cl in 4HMR
Cl in 4HMQ
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy