Fluorine in PDB 1ysi: Solution Structure of the Anti-Apoptotic Protein Bcl-Xl in Complex with An Acyl-Sulfonamide-Based Ligand

The binding sites of Fluorine atom in the Solution Structure of the Anti-Apoptotic Protein Bcl-Xl in Complex with An Acyl-Sulfonamide-Based Ligand (pdb code 1ysi). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Solution Structure of the Anti-Apoptotic Protein Bcl-Xl in Complex with An Acyl-Sulfonamide-Based Ligand, PDB code: 1ysi:

Fluorine binding site 1 out of 1 in the Solution Structure of the Anti-Apoptotic Protein Bcl-Xl in Complex with An Acyl-Sulfonamide-Based Ligand


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Solution Structure of the Anti-Apoptotic Protein Bcl-Xl in Complex with An Acyl-Sulfonamide-Based Ligand within 5.0Å range: probe atom residue distance (Å) B Occ A:F1000 b:1.0 occ:1.00 F7 A:N3B1000 0.0 1.0 1.0 C2 A:N3B1000 1.3 0.9 1.0 C1 A:N3B1000 2.4 1.5 1.0 C3 A:N3B1000 2.4 1.4 1.0 HA1 A:N3B1000 2.6 2.4 1.0 O A:ALA108 2.6 2.4 1.0 HA2 A:N3B1000 2.6 2.3 1.0 HD13 A:LEU112 2.9 1.2 1.0 HD21 A:LEU134 2.9 0.8 1.0 HD1 A:PHE109 3.0 2.2 1.0 HA A:PHE109 3.3 0.7 1.0 C A:ALA108 3.4 1.7 1.0 C4 A:N3B1000 3.6 1.4 1.0 C6 A:N3B1000 3.6 1.4 1.0 HB3 A:PHE109 3.8 1.9 1.0 HG A:LEU112 3.9 0.4 1.0 CD2 A:LEU134 3.9 0.3 1.0 CD1 A:LEU112 4.0 0.6 1.0 CA A:PHE109 4.0 0.8 1.0 CD1 A:PHE109 4.0 1.6 1.0 N A:PHE109 4.0 0.9 1.0 C5 A:N3B1000 4.1 0.7 1.0 HD22 A:LEU134 4.1 0.9 1.0 HA A:ALA108 4.1 2.5 1.0 HB2 A:ALA108 4.2 3.4 1.0 HD23 A:LEU134 4.3 1.0 1.0 CA A:ALA108 4.3 2.1 1.0 CB A:PHE109 4.4 1.3 1.0 CG A:LEU112 4.5 0.3 1.0 HB1 A:N3B1000 4.5 2.2 1.0 HB2 A:N3B1000 4.5 2.3 1.0 HD11 A:LEU112 4.5 1.3 1.0 HD12 A:LEU112 4.6 1.0 1.0 HD21 A:LEU112 4.6 1.3 1.0 CG A:PHE109 4.7 0.9 1.0 CB A:ALA108 4.8 2.7 1.0 HG A:LEU134 4.9 0.2 1.0 H A:PHE109 4.9 1.1 1.0 HE1 A:PHE109 5.0 3.0 1.0

T.Oltersdorf, S.W.Elmore, A.R.Shoemaker, R.C.Armstrong, D.J.Augeri, B.A.Belli, M.Bruncko, T.L.Deckwerth, J.Dinges, P.J.Hajduk, M.K.Joseph, S.Kitada, S.J.Korsmeyer, A.R.Kunzer, A.Letai, C.Li, M.J.Mitten, D.G.Nettesheim, S.Ng, P.M.Nimmer, J.M.O'connor, A.Oleksijew, A.M.Petros, J.C.Reed, W.Shen, S.K.Tahir, C.B.Thompson, K.J.Tomaselli, B.Wang, M.D.Wendt, H.Zhang, S.W.Fesik, S.H.Rosenberg. An Inhibitor of Bcl-2 Family Proteins Induces Regression of Solid Tumours Nature V. 435 677 2005.
ISSN: ISSN 0028-0836
PubMed: 15902208
DOI: 10.1038/NATURE03579