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Atomistry » Fluorine » PDB 2duz-2fq6 » 2ewa | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 2duz-2fq6 » 2ewa » |
Fluorine in PDB 2ewa: Dual Binding Mode of Pyridinylimidazole to Map Kinase P38Enzymatic activity of Dual Binding Mode of Pyridinylimidazole to Map Kinase P38
All present enzymatic activity of Dual Binding Mode of Pyridinylimidazole to Map Kinase P38:
2.7.1.37; Protein crystallography data
The structure of Dual Binding Mode of Pyridinylimidazole to Map Kinase P38, PDB code: 2ewa
was solved by
L.Delarbre,
S.Pouzieux,
J.-P.Guilloteau,
N.Michot,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Dual Binding Mode of Pyridinylimidazole to Map Kinase P38
(pdb code 2ewa). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Dual Binding Mode of Pyridinylimidazole to Map Kinase P38, PDB code: 2ewa: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 2ewaGo back to![]() ![]()
Fluorine binding site 1 out
of 2 in the Dual Binding Mode of Pyridinylimidazole to Map Kinase P38
![]() Mono view ![]() Stereo pair view
Fluorine binding site 2 out of 2 in 2ewaGo back to![]() ![]()
Fluorine binding site 2 out
of 2 in the Dual Binding Mode of Pyridinylimidazole to Map Kinase P38
![]() Mono view ![]() Stereo pair view
Reference:
M.Vogtherr,
K.Saxena,
S.Hoelder,
S.Grimme,
M.Betz,
U.Schieborr,
B.Pescatore,
M.Robin,
L.Delarbre,
T.Langer,
K.U.Wendt,
H.Schwalbe.
uc(Nmr) Characterization of Kinase P38 Dynamics in Free and Ligand-Bound Forms. Angew.Chem.Int.Ed.Engl. V. 45 993 2006.
Page generated: Wed Jul 31 14:07:38 2024
ISSN: ISSN 1433-7851 PubMed: 16374788 DOI: 10.1002/ANIE.200502770 |
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