Fluorine in PDB 2n7l: uc(Nmr) Structure of the N-Domain of Troponin C Bound to the Switch Region of Troponin I and the Covalent Levosimendan Analog I9

The structure of uc(Nmr) Structure of the N-Domain of Troponin C Bound to the Switch Region of Troponin I and the Covalent Levosimendan Analog I9 also contains other interesting chemical elements:

Calcium

(Ca)

20 atoms

The binding sites of Fluorine atom in the uc(Nmr) Structure of the N-Domain of Troponin C Bound to the Switch Region of Troponin I and the Covalent Levosimendan Analog I9 (pdb code 2n7l). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the uc(Nmr) Structure of the N-Domain of Troponin C Bound to the Switch Region of Troponin I and the Covalent Levosimendan Analog I9, PDB code: 2n7l:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in the uc(Nmr) Structure of the N-Domain of Troponin C Bound to the Switch Region of Troponin I and the Covalent Levosimendan Analog I9


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of uc(Nmr) Structure of the N-Domain of Troponin C Bound to the Switch Region of Troponin I and the Covalent Levosimendan Analog I9 within 5.0Å range: probe atom residue distance (Å) B Occ C:F84 b:0.0 occ:1.00 FAA C:4J484 0.0 0.0 1.0 CAB C:4J484 1.4 0.0 1.0 CAJ C:4J484 2.4 0.0 1.0 CAC C:4J484 2.4 0.0 1.0 HAC C:4J484 2.6 0.0 1.0 CAI C:4J484 2.8 0.0 1.0 CAH C:4J484 3.4 0.0 1.0 CAS C:4J484 3.4 0.0 1.0 HG22 C:VAL64 3.4 0.0 1.0 HAH C:4J484 3.6 0.0 1.0 HAS C:4J484 3.6 0.0 1.0 CAK C:4J484 3.6 0.0 1.0 CAD C:4J484 3.6 0.0 1.0 HG23 C:VAL64 4.0 0.0 1.0 CAL C:4J484 4.1 0.0 1.0 CG2 C:VAL64 4.2 0.0 1.0 HB C:VAL64 4.2 0.0 1.0 CAG C:4J484 4.4 0.0 1.0 CAR C:4J484 4.4 0.0 1.0 HG11 C:VAL64 4.4 0.0 1.0 HAK C:4J484 4.5 0.0 1.0 CB C:VAL64 4.7 0.0 1.0 FAE C:4J484 4.8 0.0 1.0 CAQ C:4J484 4.8 0.0 1.0

Fluorine binding site 2 out of 2 in the uc(Nmr) Structure of the N-Domain of Troponin C Bound to the Switch Region of Troponin I and the Covalent Levosimendan Analog I9


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of uc(Nmr) Structure of the N-Domain of Troponin C Bound to the Switch Region of Troponin I and the Covalent Levosimendan Analog I9 within 5.0Å range: probe atom residue distance (Å) B Occ C:F84 b:0.0 occ:1.00 FAE C:4J484 0.0 0.0 1.0 CAD C:4J484 1.4 0.0 1.0 CAL C:4J484 2.4 0.0 1.0 CAC C:4J484 2.4 0.0 1.0 HAL C:4J484 2.6 0.0 1.0 HAC C:4J484 2.6 0.0 1.0 HG11 C:VAL64 2.7 0.0 1.0 HG12 C:ILE61 2.7 0.0 1.0 HA C:ILE61 3.0 0.0 1.0 HD21 C:LEU41 3.3 0.0 1.0 HG13 C:ILE61 3.6 0.0 1.0 CG1 C:ILE61 3.6 0.0 1.0 CAK C:4J484 3.6 0.0 1.0 CAB C:4J484 3.7 0.0 1.0 HG22 C:VAL72 3.7 0.0 1.0 CG1 C:VAL64 3.7 0.0 1.0 CA C:ILE61 3.9 0.0 1.0 HD12 C:ILE36 3.9 0.0 1.0 HG13 C:VAL64 3.9 0.0 1.0 HD11 C:ILE36 4.0 0.0 1.0 HE3 C:MET80 4.0 0.0 1.0 CAJ C:4J484 4.1 0.0 1.0 CD2 C:LEU41 4.2 0.0 1.0 HD23 C:LEU41 4.2 0.0 1.0 HG12 C:VAL64 4.3 0.0 1.0 CB C:ILE61 4.3 0.0 1.0 HG22 C:ILE61 4.3 0.0 1.0 N C:ILE61 4.3 0.0 1.0 HB3 C:MET60 4.4 0.0 1.0 CD1 C:ILE36 4.4 0.0 1.0 HD11 C:LEU41 4.5 0.0 1.0 HB C:VAL64 4.5 0.0 1.0 SD C:MET80 4.5 0.0 1.0 O C:MET60 4.5 0.0 1.0 HAK C:4J484 4.5 0.0 1.0 C C:MET60 4.6 0.0 1.0 CG2 C:ILE61 4.7 0.0 1.0 CG2 C:VAL72 4.7 0.0 1.0 HG21 C:ILE61 4.7 0.0 1.0 HG21 C:ILE36 4.7 0.0 1.0 HG22 C:VAL64 4.7 0.0 1.0 CB C:VAL64 4.7 0.0 1.0 H C:ILE61 4.8 0.0 1.0 FAA C:4J484 4.8 0.0 1.0 CE C:MET80 4.8 0.0 1.0 HG23 C:VAL72 4.8 0.0 1.0 CD1 C:ILE61 4.8 0.0 1.0 HD12 C:LEU41 4.8 0.0 1.0 HD13 C:ILE61 4.8 0.0 1.0 HG12 C:ILE36 4.8 0.0 1.0 HD22 C:LEU41 4.9 0.0 1.0 HB2 C:LEU41 5.0 0.0 1.0 HB2 C:MET60 5.0 0.0 1.0

S.E.Pineda Sanabria, I.M.Robertson, Y.Sun, M.Irving, B.D.Sykes. Troponin C with Covalently Bound Levosimendan Analog I9 Enhances Contraction in Cardiac Muscle Fibers To Be Published.