Atomistry » Fluorine » PDB 2z78-3az8 » 3ae1
Atomistry »
  Fluorine »
    PDB 2z78-3az8 »
      3ae1 »

Fluorine in PDB 3ae1: Crystal Structure of Porcine Heart Mitochondrial Complex II Bound with N-Phenyl-2-(Trifluoromethyl)-Benzamide

Enzymatic activity of Crystal Structure of Porcine Heart Mitochondrial Complex II Bound with N-Phenyl-2-(Trifluoromethyl)-Benzamide

All present enzymatic activity of Crystal Structure of Porcine Heart Mitochondrial Complex II Bound with N-Phenyl-2-(Trifluoromethyl)-Benzamide:
1.3.5.1;

Protein crystallography data

The structure of Crystal Structure of Porcine Heart Mitochondrial Complex II Bound with N-Phenyl-2-(Trifluoromethyl)-Benzamide, PDB code: 3ae1 was solved by S.Harada, T.Sasaki, M.Shindo, Y.Kido, D.K.Inaoka, J.Omori, A.Osanai, K.Sakamoto, J.Mao, S.Matsuoka, M.Inoue, T.Honma, A.Tanaka, K.Kita, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.62 / 3.14
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 71.465, 84.065, 294.622, 90.00, 90.00, 90.00
R / Rfree (%) 22 / 26.8

Other elements in 3ae1:

The structure of Crystal Structure of Porcine Heart Mitochondrial Complex II Bound with N-Phenyl-2-(Trifluoromethyl)-Benzamide also contains other interesting chemical elements:

Iron (Fe) 10 atoms

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Crystal Structure of Porcine Heart Mitochondrial Complex II Bound with N-Phenyl-2-(Trifluoromethyl)-Benzamide (pdb code 3ae1). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structure of Porcine Heart Mitochondrial Complex II Bound with N-Phenyl-2-(Trifluoromethyl)-Benzamide, PDB code: 3ae1:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in 3ae1

Go back to Fluorine Binding Sites List in 3ae1
Fluorine binding site 1 out of 3 in the Crystal Structure of Porcine Heart Mitochondrial Complex II Bound with N-Phenyl-2-(Trifluoromethyl)-Benzamide


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of Porcine Heart Mitochondrial Complex II Bound with N-Phenyl-2-(Trifluoromethyl)-Benzamide within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F1201

b:0.3
occ:1.00
 F1 C:TFZ1201 0.0 0.3 1.0
C1 C:TFZ1201 1.3 0.9 1.0
F3 C:TFZ1201 2.1 0.6 1.0
F2 C:TFZ1201 2.2 1.0 1.0
C2 C:TFZ1201 2.3 0.9 1.0
C3 C:TFZ1201 3.2 0.9 1.0
C7 C:TFZ1201 3.3 0.9 1.0
CG2 C:ILE43 3.3 75.9 1.0
C8 C:TFZ1201 3.5 0.9 1.0
O C:TFZ1201 3.6 0.9 1.0
OH D:TYR91 4.2 84.1 1.0
N C:TFZ1201 4.3 0.9 1.0
C4 C:TFZ1201 4.4 0.8 1.0
C6 C:TFZ1201 4.5 0.8 1.0
CB C:ILE43 4.6 76.3 1.0
NE1 B:TRP173 4.7 76.5 1.0
CG1 C:ILE43 4.9 76.3 1.0
C5 C:TFZ1201 4.9 0.8 1.0

Fluorine binding site 2 out of 3 in 3ae1

Go back to Fluorine Binding Sites List in 3ae1
Fluorine binding site 2 out of 3 in the Crystal Structure of Porcine Heart Mitochondrial Complex II Bound with N-Phenyl-2-(Trifluoromethyl)-Benzamide


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Crystal Structure of Porcine Heart Mitochondrial Complex II Bound with N-Phenyl-2-(Trifluoromethyl)-Benzamide within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F1201

b:1.0
occ:1.00
 F2 C:TFZ1201 0.0 1.0 1.0
C1 C:TFZ1201 1.3 0.9 1.0
F3 C:TFZ1201 2.2 0.6 1.0
F1 C:TFZ1201 2.2 0.3 1.0
C2 C:TFZ1201 2.3 0.9 1.0
O C:TFZ1201 2.6 0.9 1.0
NE1 B:TRP173 2.9 76.5 1.0
C3 C:TFZ1201 3.0 0.9 1.0
C8 C:TFZ1201 3.1 0.9 1.0
C7 C:TFZ1201 3.4 0.9 1.0
CB B:PRO169 3.5 70.5 1.0
OH D:TYR91 3.8 84.1 1.0
CE2 B:TRP173 3.8 78.6 1.0
CD1 B:TRP173 4.0 75.0 1.0
CZ2 B:TRP173 4.0 81.0 1.0
C4 C:TFZ1201 4.3 0.8 1.0
N C:TFZ1201 4.3 0.9 1.0
CG B:PRO169 4.4 70.5 1.0
C6 C:TFZ1201 4.6 0.8 1.0
CA B:PRO169 4.8 69.5 1.0
CZ D:TYR91 4.9 82.8 1.0
C5 C:TFZ1201 5.0 0.8 1.0

Fluorine binding site 3 out of 3 in 3ae1

Go back to Fluorine Binding Sites List in 3ae1
Fluorine binding site 3 out of 3 in the Crystal Structure of Porcine Heart Mitochondrial Complex II Bound with N-Phenyl-2-(Trifluoromethyl)-Benzamide


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Crystal Structure of Porcine Heart Mitochondrial Complex II Bound with N-Phenyl-2-(Trifluoromethyl)-Benzamide within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F1201

b:0.6
occ:1.00
 F3 C:TFZ1201 0.0 0.6 1.0
C1 C:TFZ1201 1.3 0.9 1.0
F1 C:TFZ1201 2.1 0.3 1.0
F2 C:TFZ1201 2.2 1.0 1.0
C2 C:TFZ1201 2.3 0.9 1.0
C7 C:TFZ1201 2.6 0.9 1.0
C3 C:TFZ1201 3.7 0.9 1.0
CZ2 B:TRP173 3.9 81.0 1.0
C6 C:TFZ1201 4.0 0.8 1.0
CG2 C:ILE30 4.1 80.4 1.0
NE1 B:TRP173 4.2 76.5 1.0
CB B:PRO169 4.3 70.5 1.0
CE2 B:TRP173 4.4 78.6 1.0
O C:TFZ1201 4.5 0.9 1.0
C8 C:TFZ1201 4.5 0.9 1.0
CH2 C:TRP35 4.6 80.3 1.0
CG B:PRO169 4.7 70.5 1.0
C4 C:TFZ1201 4.8 0.8 1.0
CZ3 B:TRP172 4.8 76.9 1.0
C5 C:TFZ1201 4.9 0.8 1.0

Reference:

S.Harada, T.Sasaki, M.Shindo, Y.Kido, D.K.Inaoka, J.Omori, A.Osanai, K.Sakamoto, J.Mao, S.Matsuoka, M.Inoue, T.Honma, A.Tanaka, K.Kita. Crystal Structure of Porcine Heart Mitochondrial Complex II Bound with N-Phenyl-2-(Trifluoromethyl)-Benzamide To Be Published.
Page generated: Mon Jul 14 15:11:17 2025

Last articles

Fe in 2C3M
Fe in 2C2F
Fe in 2C2C
Fe in 2C2U
Fe in 2C2J
Fe in 2C1D
Fe in 2C1U
Fe in 2C1V
Fe in 2BW1
Fe in 2C0K
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy