Fluorine in PDB 3dll: The Oxazolidinone Antibiotics Perturb the Ribosomal Peptidyl- Transferase Center and Effect Trna Positioning

The structure of The Oxazolidinone Antibiotics Perturb the Ribosomal Peptidyl- Transferase Center and Effect Trna Positioning, PDB code: 3dll was solved by D.N.Wilson, F.Schluenzen, J.M.Harms, A.L.Starosta, S.R.Connell, P.Fucini, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.98 / 3.50
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	169.700, 410.000, 695.000, 90.00, 90.00, 90.00
R / Rfree (%)	25.9 / 28

The structure of The Oxazolidinone Antibiotics Perturb the Ribosomal Peptidyl- Transferase Center and Effect Trna Positioning also contains other interesting chemical elements:

Magnesium	(Mg)	35 atoms
Zinc	(Zn)	2 atoms

The binding sites of Fluorine atom in the The Oxazolidinone Antibiotics Perturb the Ribosomal Peptidyl- Transferase Center and Effect Trna Positioning (pdb code 3dll). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the The Oxazolidinone Antibiotics Perturb the Ribosomal Peptidyl- Transferase Center and Effect Trna Positioning, PDB code: 3dll:

Fluorine binding site 1 out of 1 in the The Oxazolidinone Antibiotics Perturb the Ribosomal Peptidyl- Transferase Center and Effect Trna Positioning


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of The Oxazolidinone Antibiotics Perturb the Ribosomal Peptidyl- Transferase Center and Effect Trna Positioning within 5.0Å range: probe atom residue distance (Å) B Occ X:F2911 b:37.7 occ:1.00 F18 X:ZLD2911 0.0 37.7 1.0 C16 X:ZLD2911 1.3 32.9 1.0 C5 X:ZLD2911 2.4 31.7 1.0 C17 X:ZLD2911 2.4 31.2 1.0 C20 X:ZLD2911 2.6 31.4 1.0 N19 X:ZLD2911 2.8 30.1 1.0 MG X:MG2908 3.3 48.2 1.0 C3 X:ZLD2911 3.7 31.5 1.0 C2 X:ZLD2911 3.7 30.3 1.0 C21 X:ZLD2911 3.9 33.5 1.0 C6 X:U2485 4.1 21.1 1.0 C1 X:ZLD2911 4.1 30.5 1.0 C24 X:ZLD2911 4.2 28.3 1.0 C5 X:U2485 4.5 22.9 1.0 O4' X:U2485 4.6 14.5 1.0 N1 X:U2485 4.7 21.7 1.0 N4 X:ZLD2911 4.8 30.9 1.0 C2 X:A2430 4.9 1.1 1.0 C1' X:U2485 4.9 17.3 1.0

D.N.Wilson, F.Schluenzen, J.M.Harms, A.L.Starosta, S.R.Connell, P.Fucini. The Oxazolidinone Antibiotics Perturb the Ribosomal Peptidyl-Transferase Center and Effect Trna Positioning Proc.Natl.Acad.Sci.Usa V. 105 13339 2008.
ISSN: ISSN 0027-8424
PubMed: 18757750
DOI: 10.1073/PNAS.0804276105