|
Atomistry » Fluorine » PDB 3dv3-3ev4 » 3ekk | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 3dv3-3ev4 » 3ekk » |
Fluorine in PDB 3ekk: Insulin Receptor Kinase Complexed with An InhibitorEnzymatic activity of Insulin Receptor Kinase Complexed with An Inhibitor
All present enzymatic activity of Insulin Receptor Kinase Complexed with An Inhibitor:
2.7.10.1; Protein crystallography data
The structure of Insulin Receptor Kinase Complexed with An Inhibitor, PDB code: 3ekk
was solved by
S.Chamberlain,
C.Atkins,
F.Deanda,
M.Dumble,
R.Gerding,
A.Groy,
S.Korenchuk,
R.Kumar,
H.Lei,
R.Mook,
G.Moorthy,
A.Redman,
J.Rowland,
P.Sabbatini,
L.Shewchuk,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Insulin Receptor Kinase Complexed with An Inhibitor
(pdb code 3ekk). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Insulin Receptor Kinase Complexed with An Inhibitor, PDB code: 3ekk: Fluorine binding site 1 out of 1 in 3ekkGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Insulin Receptor Kinase Complexed with An Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
S.D.Chamberlain,
J.W.Wilson,
F.Deanda,
S.Patnaik,
A.M.Redman,
B.Yang,
L.Shewchuk,
P.Sabbatini,
M.A.Leesnitzer,
A.Groy,
C.Atkins,
R.Gerding,
A.M.Hassell,
H.Lei,
R.A.Mook,
G.Moorthy,
J.L.Rowand,
K.L.Stevens,
R.Kumar,
J.B.Shotwell.
Discovery of 4,6-Bis-Anilino-1H-Pyrrolo[2,3-D]Pyrimidines: Potent Inhibitors of the Igf-1R Receptor Tyrosine Kinase. Bioorg.Med.Chem.Lett. V. 19 469 2009.
Page generated: Mon Jul 14 16:06:31 2025
ISSN: ISSN 0960-894X PubMed: 19056263 DOI: 10.1016/J.BMCL.2008.11.046 |
Last articlesFe in 2YXOFe in 2YRS Fe in 2YXC Fe in 2YNM Fe in 2YVJ Fe in 2YP1 Fe in 2YU2 Fe in 2YU1 Fe in 2YQB Fe in 2YOO |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |