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Atomistry » Fluorine » PDB 3ewh-3flq » 3fkt » |
Fluorine in PDB 3fkt: Crystal Structure of Human Beta Secretase Complexed with Spiropiperdine Iminohydantoin InhibitorEnzymatic activity of Crystal Structure of Human Beta Secretase Complexed with Spiropiperdine Iminohydantoin Inhibitor
All present enzymatic activity of Crystal Structure of Human Beta Secretase Complexed with Spiropiperdine Iminohydantoin Inhibitor:
3.4.23.46; Protein crystallography data
The structure of Crystal Structure of Human Beta Secretase Complexed with Spiropiperdine Iminohydantoin Inhibitor, PDB code: 3fkt
was solved by
S.Munshi,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Human Beta Secretase Complexed with Spiropiperdine Iminohydantoin Inhibitor
(pdb code 3fkt). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of Human Beta Secretase Complexed with Spiropiperdine Iminohydantoin Inhibitor, PDB code: 3fkt: Fluorine binding site 1 out of 1 in 3fktGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Crystal Structure of Human Beta Secretase Complexed with Spiropiperdine Iminohydantoin Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
J.C.Barrow,
S.R.Stauffer,
K.E.Rittle,
P.L.Ngo,
M.S.Yang,
S.Graham,
G.Mcgaughey,
K.Holloway,
S.K.Tugusheva,
M.Lai,
A.S.Espeseth,
M.Xu,
Q.Huang,
P.Zuck,
D.A.Levorse,
D.Hazuda,
J.P.Vacca.
Discovery and X-Ray Crystallographic Analysis of A Iminohydantoin Inhibitor of Beta-Secretase J.Med.Chem. V. 51 6259 2008.
Page generated: Wed Jul 31 18:34:25 2024
ISSN: ISSN 0022-2623 PubMed: 18811140 DOI: 10.1021/JM800914N |
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