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Atomistry » Fluorine » PDB 3fls-3g70 » 3fu0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 3fls-3g70 » 3fu0 » |
Fluorine in PDB 3fu0: Leukotriene A4 Hydrolase in Complex with Fragment 4-(4- Fluorobenzoyl)PyridineEnzymatic activity of Leukotriene A4 Hydrolase in Complex with Fragment 4-(4- Fluorobenzoyl)Pyridine
All present enzymatic activity of Leukotriene A4 Hydrolase in Complex with Fragment 4-(4- Fluorobenzoyl)Pyridine:
3.3.2.6; Protein crystallography data
The structure of Leukotriene A4 Hydrolase in Complex with Fragment 4-(4- Fluorobenzoyl)Pyridine, PDB code: 3fu0
was solved by
D.R.Davies,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3fu0:
The structure of Leukotriene A4 Hydrolase in Complex with Fragment 4-(4- Fluorobenzoyl)Pyridine also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Leukotriene A4 Hydrolase in Complex with Fragment 4-(4- Fluorobenzoyl)Pyridine
(pdb code 3fu0). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Leukotriene A4 Hydrolase in Complex with Fragment 4-(4- Fluorobenzoyl)Pyridine, PDB code: 3fu0: Fluorine binding site 1 out of 1 in 3fu0Go back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Leukotriene A4 Hydrolase in Complex with Fragment 4-(4- Fluorobenzoyl)Pyridine
![]() Mono view ![]() Stereo pair view
Reference:
D.R.Davies,
B.Mamat,
O.T.Magnusson,
J.Christensen,
M.H.Haraldsson,
R.Mishra,
B.Pease,
E.Hansen,
J.Singh,
D.Zembower,
H.Kim,
A.S.Kiselyov,
A.B.Burgin,
M.E.Gurney,
L.J.Stewart.
Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography. J.Med.Chem. V. 52 4694 2009.
Page generated: Mon Jul 14 16:23:50 2025
ISSN: ISSN 0022-2623 PubMed: 19618939 DOI: 10.1021/JM900259H |
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