Atomistry » Fluorine » PDB 3fls-3g70 » 3fxw
Atomistry »
  Fluorine »
    PDB 3fls-3g70 »
      3fxw »

Fluorine in PDB 3fxw: High Resolution Crystal Structure of Mitogen-Activated Protein Kinase- Activated Protein Kinase 3/Inhibitor 2 Complex

Enzymatic activity of High Resolution Crystal Structure of Mitogen-Activated Protein Kinase- Activated Protein Kinase 3/Inhibitor 2 Complex

All present enzymatic activity of High Resolution Crystal Structure of Mitogen-Activated Protein Kinase- Activated Protein Kinase 3/Inhibitor 2 Complex:
2.7.11.1;

Protein crystallography data

The structure of High Resolution Crystal Structure of Mitogen-Activated Protein Kinase- Activated Protein Kinase 3/Inhibitor 2 Complex, PDB code: 3fxw was solved by R.K.Y.Cheng, J.Barker, S.Palan, B.Felicetti, M.Whittaker, T.Hesterkamp, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 27.58 / 2.00
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 85.294, 75.555, 61.731, 90.00, 108.91, 90.00
R / Rfree (%) 23.3 / 27.7

Fluorine Binding Sites:

The binding sites of Fluorine atom in the High Resolution Crystal Structure of Mitogen-Activated Protein Kinase- Activated Protein Kinase 3/Inhibitor 2 Complex (pdb code 3fxw). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the High Resolution Crystal Structure of Mitogen-Activated Protein Kinase- Activated Protein Kinase 3/Inhibitor 2 Complex, PDB code: 3fxw:

Fluorine binding site 1 out of 1 in 3fxw

Go back to Fluorine Binding Sites List in 3fxw
Fluorine binding site 1 out of 1 in the High Resolution Crystal Structure of Mitogen-Activated Protein Kinase- Activated Protein Kinase 3/Inhibitor 2 Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of High Resolution Crystal Structure of Mitogen-Activated Protein Kinase- Activated Protein Kinase 3/Inhibitor 2 Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1

b:46.9
occ:1.00
 F6 A:F101 0.0 46.9 1.0
C5 A:F101 1.3 42.8 1.0
C7 A:F101 2.4 42.0 1.0
C4 A:F101 2.4 38.6 1.0
C11 A:F101 2.9 34.6 1.0
O A:HOH433 2.9 34.5 1.0
C2 A:F101 3.0 37.7 1.0
O A:HOH392 3.2 58.3 1.0
O A:LEU50 3.6 70.1 1.0
C8 A:F101 3.6 41.1 1.0
C10 A:F101 3.7 42.7 1.0
O A:MET121 3.7 39.3 1.0
CG A:LEU173 4.1 51.5 1.0
C9 A:F101 4.1 43.5 1.0
CA A:GLY124 4.1 50.3 1.0
C12 A:F101 4.1 30.7 1.0
N23 A:F101 4.2 34.9 1.0
CD2 A:LEU173 4.2 51.6 1.0
CD1 A:LEU173 4.4 51.8 1.0
N20 A:F101 4.5 31.3 1.0
C A:LEU50 4.6 69.9 1.0
CB A:LEU50 4.7 68.6 1.0
CB A:MET121 4.7 38.8 1.0
C A:MET121 4.8 40.5 1.0
N A:GLY124 4.8 49.9 1.0
C13 A:F101 4.9 32.2 1.0
C A:GLY124 4.9 51.0 1.0

Reference:

R.K.Y.Cheng, J.Barker, S.Palan, B.Felicetti, M.Whittaker, T.Hesterkamp. High Resolution Crystal Structure of Mitogen-Activated Protein Kinase-Activated Protein Kinase 3/Inhibitor 2 Complex To Be Published.
Page generated: Wed Jul 31 18:41:55 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy