|
Atomistry » Fluorine » PDB 3hky-3ig6 » 3hvk | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 3hky-3ig6 » 3hvk » |
Fluorine in PDB 3hvk: Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, Purine-Containing Bisubstrate Inhibitor - Humanized FormEnzymatic activity of Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, Purine-Containing Bisubstrate Inhibitor - Humanized Form
All present enzymatic activity of Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, Purine-Containing Bisubstrate Inhibitor - Humanized Form:
2.1.1.6; Protein crystallography data
The structure of Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, Purine-Containing Bisubstrate Inhibitor - Humanized Form, PDB code: 3hvk
was solved by
A.Ehler,
D.Schlatter,
M.Stihle,
J.Benz,
M.G.Rudolph,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3hvk:
The structure of Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, Purine-Containing Bisubstrate Inhibitor - Humanized Form also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, Purine-Containing Bisubstrate Inhibitor - Humanized Form
(pdb code 3hvk). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, Purine-Containing Bisubstrate Inhibitor - Humanized Form, PDB code: 3hvk: Fluorine binding site 1 out of 1 in 3hvkGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, Purine-Containing Bisubstrate Inhibitor - Humanized Form
![]() Mono view ![]() Stereo pair view
Reference:
M.Ellermann,
R.Jakob-Roetne,
C.Lerner,
E.Borroni,
D.Schlatter,
D.Roth,
A.Ehler,
M.G.Rudolph,
F.Diederich.
Molecular Recognition at the Active Site of Catechol-O-Methyltransferase: Energetically Favorable Replacement of A Water Molecule Imported By A Bisubstrate Inhibitor. Angew.Chem.Int.Ed.Engl. V. 48 9092 2009.
Page generated: Mon Jul 14 16:56:29 2025
ISSN: ISSN 1433-7851 PubMed: 19882607 DOI: 10.1002/ANIE.200904410 |
Last articlesFe in 2YXOFe in 2YRS Fe in 2YXC Fe in 2YNM Fe in 2YVJ Fe in 2YP1 Fe in 2YU2 Fe in 2YU1 Fe in 2YQB Fe in 2YOO |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |