Atomistry » Fluorine » PDB 3n2m-3nly » 3n34
Atomistry »
  Fluorine »
    PDB 3n2m-3nly »
      3n34 »

Fluorine in PDB 3n34: Crystal Structure of Plasmodium Falciparum Orotidine 5'-Monophosphate Decarboxylase Complexed with 5-Fluoro-6-Amino-Ump, Produced From 5- Fluoro-6-Azido-Ump

Enzymatic activity of Crystal Structure of Plasmodium Falciparum Orotidine 5'-Monophosphate Decarboxylase Complexed with 5-Fluoro-6-Amino-Ump, Produced From 5- Fluoro-6-Azido-Ump

All present enzymatic activity of Crystal Structure of Plasmodium Falciparum Orotidine 5'-Monophosphate Decarboxylase Complexed with 5-Fluoro-6-Amino-Ump, Produced From 5- Fluoro-6-Azido-Ump:
4.1.1.23;

Protein crystallography data

The structure of Crystal Structure of Plasmodium Falciparum Orotidine 5'-Monophosphate Decarboxylase Complexed with 5-Fluoro-6-Amino-Ump, Produced From 5- Fluoro-6-Azido-Ump, PDB code: 3n34 was solved by Y.Liu, L.P.Kotra, E.F.Pai, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 1.55
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 80.339, 83.085, 89.857, 90.00, 90.00, 90.00
R / Rfree (%) 15.6 / 18.2

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Crystal Structure of Plasmodium Falciparum Orotidine 5'-Monophosphate Decarboxylase Complexed with 5-Fluoro-6-Amino-Ump, Produced From 5- Fluoro-6-Azido-Ump (pdb code 3n34). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of Plasmodium Falciparum Orotidine 5'-Monophosphate Decarboxylase Complexed with 5-Fluoro-6-Amino-Ump, Produced From 5- Fluoro-6-Azido-Ump, PDB code: 3n34:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in 3n34

Go back to Fluorine Binding Sites List in 3n34
Fluorine binding site 1 out of 2 in the Crystal Structure of Plasmodium Falciparum Orotidine 5'-Monophosphate Decarboxylase Complexed with 5-Fluoro-6-Amino-Ump, Produced From 5- Fluoro-6-Azido-Ump


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of Plasmodium Falciparum Orotidine 5'-Monophosphate Decarboxylase Complexed with 5-Fluoro-6-Amino-Ump, Produced From 5- Fluoro-6-Azido-Ump within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1000

b:12.7
occ:1.00
 F24 A:FNU1000 0.0 12.7 1.0
C5 A:FNU1000 1.4 10.1 1.0
C6 A:FNU1000 2.4 9.3 1.0
C4 A:FNU1000 2.4 10.1 1.0
N3 A:FNU1000 2.7 15.7 1.0
O4 A:FNU1000 2.8 10.9 1.0
CE A:LYS138 3.3 8.1 0.4
CG1 A:VAL240 3.4 8.9 1.0
CD2 A:LEU191 3.6 9.3 1.0
N1 A:FNU1000 3.6 7.7 1.0
N2 A:FNU1000 3.6 7.8 1.0
CG2 A:THR194 3.8 9.5 1.0
NZ A:LYS138 4.0 10.6 0.4
C2 A:FNU1000 4.1 9.1 1.0
CE B:MET168 4.2 17.8 1.0
CB A:VAL240 4.4 6.8 1.0
CB A:THR194 4.5 7.6 1.0
CD A:LYS138 4.5 7.2 0.4
CG A:PRO264 4.6 8.7 1.0
CG2 A:VAL240 4.7 7.2 1.0
CG A:LEU191 4.7 7.8 1.0
CD1 A:LEU191 4.8 9.5 1.0
C1' A:FNU1000 4.8 9.4 1.0
SD B:MET168 4.9 14.0 1.0

Fluorine binding site 2 out of 2 in 3n34

Go back to Fluorine Binding Sites List in 3n34
Fluorine binding site 2 out of 2 in the Crystal Structure of Plasmodium Falciparum Orotidine 5'-Monophosphate Decarboxylase Complexed with 5-Fluoro-6-Amino-Ump, Produced From 5- Fluoro-6-Azido-Ump


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Crystal Structure of Plasmodium Falciparum Orotidine 5'-Monophosphate Decarboxylase Complexed with 5-Fluoro-6-Amino-Ump, Produced From 5- Fluoro-6-Azido-Ump within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F1001

b:13.2
occ:1.00
 F24 B:FNU1001 0.0 13.2 1.0
C5 B:FNU1001 1.4 10.4 1.0
C6 B:FNU1001 2.3 9.3 1.0
C4 B:FNU1001 2.4 11.1 1.0
N3 B:FNU1001 2.7 13.5 1.0
O4 B:FNU1001 2.8 12.4 1.0
CE B:LYS138 3.4 9.8 0.5
CD2 B:LEU191 3.5 13.1 1.0
CG1 B:VAL240 3.5 9.0 1.0
N1 B:FNU1001 3.6 9.1 1.0
N2 B:FNU1001 3.6 9.0 1.0
CE A:MET168 3.8 17.4 1.0
CG2 B:THR194 3.9 10.9 1.0
C2 B:FNU1001 4.0 8.9 1.0
NZ B:LYS138 4.1 7.8 0.5
CB B:VAL240 4.4 8.3 1.0
CB B:THR194 4.5 9.7 1.0
CD B:LYS138 4.6 7.2 0.5
CG B:PRO264 4.6 8.5 1.0
CG B:LEU191 4.6 11.2 1.0
CD1 B:LEU191 4.7 11.9 1.0
C1' B:FNU1001 4.8 9.4 1.0
SD A:MET168 4.8 15.0 1.0
CG2 B:VAL240 4.8 8.8 1.0
CA B:THR194 5.0 9.7 1.0

Reference:

Y.Liu, L.P.Kotra, E.F.Pai. Crystal Structure of Plasmodium Falciparum Orotidine 5'-Monophosphate Decarboxylase Complexed with 5-Fluoro-6-Amino-Ump, Produced From 5-Fluoro-6-Azido-Ump To Be Published.
Page generated: Mon Jul 14 18:00:02 2025

Last articles

Mn in 9LJU
Mn in 9LJW
Mn in 9LJS
Mn in 9LJR
Mn in 9LJT
Mn in 9LJV
Mg in 9UA2
Mg in 9R96
Mg in 9VM1
Mg in 9P01
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy