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Atomistry » Fluorine » PDB 3nlz-3og7 » 3nw5 » |
Fluorine in PDB 3nw5: Crystal Structure of Insulin-Like Growth Factor 1 Receptor (Igf-1R-Wt) Complex with A Carbon-Linked Proline Isostere Inhibitor (11B)Enzymatic activity of Crystal Structure of Insulin-Like Growth Factor 1 Receptor (Igf-1R-Wt) Complex with A Carbon-Linked Proline Isostere Inhibitor (11B)
All present enzymatic activity of Crystal Structure of Insulin-Like Growth Factor 1 Receptor (Igf-1R-Wt) Complex with A Carbon-Linked Proline Isostere Inhibitor (11B):
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of Insulin-Like Growth Factor 1 Receptor (Igf-1R-Wt) Complex with A Carbon-Linked Proline Isostere Inhibitor (11B), PDB code: 3nw5
was solved by
J.S.Sack,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Insulin-Like Growth Factor 1 Receptor (Igf-1R-Wt) Complex with A Carbon-Linked Proline Isostere Inhibitor (11B)
(pdb code 3nw5). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of Insulin-Like Growth Factor 1 Receptor (Igf-1R-Wt) Complex with A Carbon-Linked Proline Isostere Inhibitor (11B), PDB code: 3nw5: Fluorine binding site 1 out of 1 in 3nw5Go back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Crystal Structure of Insulin-Like Growth Factor 1 Receptor (Igf-1R-Wt) Complex with A Carbon-Linked Proline Isostere Inhibitor (11B)
![]() Mono view ![]() Stereo pair view
Reference:
A.J.Sampognaro,
M.D.Wittman,
J.M.Carboni,
C.Chang,
A.F.Greer,
W.W.Hurlburt,
J.S.Sack,
D.M.Vyas.
Proline Isosteres in A Series of 2,4-Disubstituted Pyrrolo[1,2-F][1,2,4]Triazine Inhibitors of Igf-1R Kinase and Ir Kinase. Bioorg.Med.Chem.Lett. V. 20 5027 2010.
Page generated: Mon Jul 14 18:12:50 2025
ISSN: ISSN 0960-894X PubMed: 20675137 DOI: 10.1016/J.BMCL.2010.07.045 |
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