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Fluorine in PDB 3sd0: Identification of A Glycogen Synthase Kinase-3B Inhibitor That Attenuates Hyperactivity in Clock Mutant Mice
Enzymatic activity of Identification of A Glycogen Synthase Kinase-3B Inhibitor That Attenuates Hyperactivity in Clock Mutant Mice
All present enzymatic activity of Identification of A Glycogen Synthase Kinase-3B Inhibitor That Attenuates Hyperactivity in Clock Mutant Mice:
2.7.11.26;
2.7.11.26;
Protein crystallography data
The structure of Identification of A Glycogen Synthase Kinase-3B Inhibitor That Attenuates Hyperactivity in Clock Mutant Mice, PDB code: 3sd0
was solved by
A.M.Mesecar,
R.L.Walters,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 44.95 / 2.70 |
| Space group | P 21 2 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 88.505, 96.010, 124.249, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 17.9 / 25.4 |
Other elements in 3sd0:
The structure of Identification of A Glycogen Synthase Kinase-3B Inhibitor That Attenuates Hyperactivity in Clock Mutant Mice also contains other interesting chemical elements:
| Iodine | (I) | 2 atoms |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Identification of A Glycogen Synthase Kinase-3B Inhibitor That Attenuates Hyperactivity in Clock Mutant Mice
(pdb code 3sd0). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Identification of A Glycogen Synthase Kinase-3B Inhibitor That Attenuates Hyperactivity in Clock Mutant Mice, PDB code: 3sd0:
Jump to Fluorine binding site number: 1; 2;
In total 2 binding sites of Fluorine where determined in the Identification of A Glycogen Synthase Kinase-3B Inhibitor That Attenuates Hyperactivity in Clock Mutant Mice, PDB code: 3sd0:
Jump to Fluorine binding site number: 1; 2;
Fluorine binding site 1 out of 2 in 3sd0
Go back to
Fluorine Binding Sites List in 3sd0
Fluorine binding site 1 out
of 2 in the Identification of A Glycogen Synthase Kinase-3B Inhibitor That Attenuates Hyperactivity in Clock Mutant Mice
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Identification of A Glycogen Synthase Kinase-3B Inhibitor That Attenuates Hyperactivity in Clock Mutant Mice within 5.0Å range:
|
Fluorine binding site 2 out of 2 in 3sd0
Go back to
Fluorine Binding Sites List in 3sd0
Fluorine binding site 2 out
of 2 in the Identification of A Glycogen Synthase Kinase-3B Inhibitor That Attenuates Hyperactivity in Clock Mutant Mice
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Identification of A Glycogen Synthase Kinase-3B Inhibitor That Attenuates Hyperactivity in Clock Mutant Mice within 5.0Å range:
|
Reference:
A.M.Mesecar,
R.L.Walters.
Identification of A Glycogen Synthase Kinase-3B Inhibitor That Attenuates Hyperactivity in Clock Mutant Mice To Be Published.
Page generated: Mon Jul 14 19:17:09 2025
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