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Atomistry » Fluorine » PDB 3u5k-3uxm » 3u5k » |
Fluorine in PDB 3u5k: Crystal Structure of the First Bromodomain of Human BRD4 in Complex with MidazolamProtein crystallography data
The structure of Crystal Structure of the First Bromodomain of Human BRD4 in Complex with Midazolam, PDB code: 3u5k
was solved by
P.Filippakopoulos,
S.Picaud,
I.Felletar,
O.Fedorov,
F.Von Delft,
C.H.Arrowsmith,
A.M.Edwards,
J.Weigelt,
C.Bountra,
S.Knapp,
Structuralgenomics Consortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3u5k:
The structure of Crystal Structure of the First Bromodomain of Human BRD4 in Complex with Midazolam also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of the First Bromodomain of Human BRD4 in Complex with Midazolam
(pdb code 3u5k). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Crystal Structure of the First Bromodomain of Human BRD4 in Complex with Midazolam, PDB code: 3u5k: Jump to Fluorine binding site number: 1; 2; 3; 4; Fluorine binding site 1 out of 4 in 3u5kGo back to![]() ![]()
Fluorine binding site 1 out
of 4 in the Crystal Structure of the First Bromodomain of Human BRD4 in Complex with Midazolam
![]() Mono view ![]() Stereo pair view
Fluorine binding site 2 out of 4 in 3u5kGo back to![]() ![]()
Fluorine binding site 2 out
of 4 in the Crystal Structure of the First Bromodomain of Human BRD4 in Complex with Midazolam
![]() Mono view ![]() Stereo pair view
Fluorine binding site 3 out of 4 in 3u5kGo back to![]() ![]()
Fluorine binding site 3 out
of 4 in the Crystal Structure of the First Bromodomain of Human BRD4 in Complex with Midazolam
![]() Mono view ![]() Stereo pair view
Fluorine binding site 4 out of 4 in 3u5kGo back to![]() ![]()
Fluorine binding site 4 out
of 4 in the Crystal Structure of the First Bromodomain of Human BRD4 in Complex with Midazolam
![]() Mono view ![]() Stereo pair view
Reference:
P.Filippakopoulos,
S.Picaud,
O.Fedorov,
M.Keller,
M.Wrobel,
O.Morgenstern,
F.Bracher,
S.Knapp.
Benzodiazepines and Benzotriazepines As Protein Interaction Inhibitors Targeting Bromodomains of the Bet Family. Bioorg.Med.Chem. V. 20 1878 2012.
Page generated: Wed Jul 31 23:00:28 2024
ISSN: ISSN 0968-0896 PubMed: 22137933 DOI: 10.1016/J.BMC.2011.10.080 |
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