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Atomistry » Fluorine » PDB 4gpb-4hw7 » 4hpx | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 4gpb-4hw7 » 4hpx » |
Fluorine in PDB 4hpx: Crystal Structure of Tryptophan Synthase at 1.65 A Resolution in Complex with Alpha Aminoacrylate E(A-A) and Benzimidazole in the Beta Site and the F9 Inhibitor in the Alpha SiteEnzymatic activity of Crystal Structure of Tryptophan Synthase at 1.65 A Resolution in Complex with Alpha Aminoacrylate E(A-A) and Benzimidazole in the Beta Site and the F9 Inhibitor in the Alpha Site
All present enzymatic activity of Crystal Structure of Tryptophan Synthase at 1.65 A Resolution in Complex with Alpha Aminoacrylate E(A-A) and Benzimidazole in the Beta Site and the F9 Inhibitor in the Alpha Site:
4.2.1.20; Protein crystallography data
The structure of Crystal Structure of Tryptophan Synthase at 1.65 A Resolution in Complex with Alpha Aminoacrylate E(A-A) and Benzimidazole in the Beta Site and the F9 Inhibitor in the Alpha Site, PDB code: 4hpx
was solved by
E.Hilario,
D.Niks,
M.F.Dunn,
L.J.Mueller,
L.Fan,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4hpx:
The structure of Crystal Structure of Tryptophan Synthase at 1.65 A Resolution in Complex with Alpha Aminoacrylate E(A-A) and Benzimidazole in the Beta Site and the F9 Inhibitor in the Alpha Site also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Tryptophan Synthase at 1.65 A Resolution in Complex with Alpha Aminoacrylate E(A-A) and Benzimidazole in the Beta Site and the F9 Inhibitor in the Alpha Site
(pdb code 4hpx). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structure of Tryptophan Synthase at 1.65 A Resolution in Complex with Alpha Aminoacrylate E(A-A) and Benzimidazole in the Beta Site and the F9 Inhibitor in the Alpha Site, PDB code: 4hpx: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 4hpxGo back to![]() ![]()
Fluorine binding site 1 out
of 3 in the Crystal Structure of Tryptophan Synthase at 1.65 A Resolution in Complex with Alpha Aminoacrylate E(A-A) and Benzimidazole in the Beta Site and the F9 Inhibitor in the Alpha Site
![]() Mono view ![]() Stereo pair view
Fluorine binding site 2 out of 3 in 4hpxGo back to![]() ![]()
Fluorine binding site 2 out
of 3 in the Crystal Structure of Tryptophan Synthase at 1.65 A Resolution in Complex with Alpha Aminoacrylate E(A-A) and Benzimidazole in the Beta Site and the F9 Inhibitor in the Alpha Site
![]() Mono view ![]() Stereo pair view
Fluorine binding site 3 out of 3 in 4hpxGo back to![]() ![]()
Fluorine binding site 3 out
of 3 in the Crystal Structure of Tryptophan Synthase at 1.65 A Resolution in Complex with Alpha Aminoacrylate E(A-A) and Benzimidazole in the Beta Site and the F9 Inhibitor in the Alpha Site
![]() Mono view ![]() Stereo pair view
Reference:
D.Niks,
E.Hilario,
A.Dierkers,
H.Ngo,
D.Borchardt,
T.J.Neubauer,
L.Fan,
L.J.Mueller,
M.F.Dunn.
Allostery and Substrate Channeling in the Tryptophan Synthase Bienzyme Complex: Evidence For Two Subunit Conformations and Four Quaternary States. Biochemistry V. 52 6396 2013.
Page generated: Mon Jul 14 22:01:22 2025
ISSN: ISSN 0006-2960 PubMed: 23952479 DOI: 10.1021/BI400795E |
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