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Fluorine in PDB 4k4i: Ternary Crystal Structures of A Human Dna Polymerase Lambda in Complex with Dna and (-)Ftc-Tp.
Enzymatic activity of Ternary Crystal Structures of A Human Dna Polymerase Lambda in Complex with Dna and (-)Ftc-Tp.
All present enzymatic activity of Ternary Crystal Structures of A Human Dna Polymerase Lambda in Complex with Dna and (-)Ftc-Tp.:
2.7.7.7;
2.7.7.7;
Protein crystallography data
The structure of Ternary Crystal Structures of A Human Dna Polymerase Lambda in Complex with Dna and (-)Ftc-Tp., PDB code: 4k4i
was solved by
R.Vyas,
Z.Suo,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 45.03 / 2.25 |
| Space group | P 21 21 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 194.440, 97.580, 105.150, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 21.2 / 27.4 |
Other elements in 4k4i:
The structure of Ternary Crystal Structures of A Human Dna Polymerase Lambda in Complex with Dna and (-)Ftc-Tp. also contains other interesting chemical elements:
| Arsenic | (As) | 2 atoms |
| Calcium | (Ca) | 23 atoms |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Ternary Crystal Structures of A Human Dna Polymerase Lambda in Complex with Dna and (-)Ftc-Tp.
(pdb code 4k4i). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Ternary Crystal Structures of A Human Dna Polymerase Lambda in Complex with Dna and (-)Ftc-Tp., PDB code: 4k4i:
Jump to Fluorine binding site number: 1; 2; 3; 4;
In total 4 binding sites of Fluorine where determined in the Ternary Crystal Structures of A Human Dna Polymerase Lambda in Complex with Dna and (-)Ftc-Tp., PDB code: 4k4i:
Jump to Fluorine binding site number: 1; 2; 3; 4;
Fluorine binding site 1 out of 4 in 4k4i
Go back to
Fluorine Binding Sites List in 4k4i
Fluorine binding site 1 out
of 4 in the Ternary Crystal Structures of A Human Dna Polymerase Lambda in Complex with Dna and (-)Ftc-Tp.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Ternary Crystal Structures of A Human Dna Polymerase Lambda in Complex with Dna and (-)Ftc-Tp. within 5.0Å range:
|
Fluorine binding site 2 out of 4 in 4k4i
Go back to
Fluorine Binding Sites List in 4k4i
Fluorine binding site 2 out
of 4 in the Ternary Crystal Structures of A Human Dna Polymerase Lambda in Complex with Dna and (-)Ftc-Tp.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Ternary Crystal Structures of A Human Dna Polymerase Lambda in Complex with Dna and (-)Ftc-Tp. within 5.0Å range:
|
Fluorine binding site 3 out of 4 in 4k4i
Go back to
Fluorine Binding Sites List in 4k4i
Fluorine binding site 3 out
of 4 in the Ternary Crystal Structures of A Human Dna Polymerase Lambda in Complex with Dna and (-)Ftc-Tp.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Ternary Crystal Structures of A Human Dna Polymerase Lambda in Complex with Dna and (-)Ftc-Tp. within 5.0Å range:
|
Fluorine binding site 4 out of 4 in 4k4i
Go back to
Fluorine Binding Sites List in 4k4i
Fluorine binding site 4 out
of 4 in the Ternary Crystal Structures of A Human Dna Polymerase Lambda in Complex with Dna and (-)Ftc-Tp.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Ternary Crystal Structures of A Human Dna Polymerase Lambda in Complex with Dna and (-)Ftc-Tp. within 5.0Å range:
|
Reference:
R.Vyas,
W.J.Zahurancik,
Z.Suo.
Structural Basis For the Binding and Incorporation of Nucleotide Analogs with L-Stereochemistry By Human Dna Polymerase Lambda. Proc.Natl.Acad.Sci.Usa V. 111 E3033 2014.
ISSN: ISSN 0027-8424
PubMed: 25015085
DOI: 10.1073/PNAS.1401286111
Page generated: Mon Jul 14 22:47:31 2025
ISSN: ISSN 0027-8424
PubMed: 25015085
DOI: 10.1073/PNAS.1401286111
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