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PDB 4olm-4pa0 »
4p75 »
Fluorine in PDB 4p75: Phers in Complex with Compound 4A
Enzymatic activity of Phers in Complex with Compound 4A
All present enzymatic activity of Phers in Complex with Compound 4A:
6.1.1.20;
6.1.1.20;
Protein crystallography data
The structure of Phers in Complex with Compound 4A, PDB code: 4p75
was solved by
A.D.Ferguson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 59.20 / 2.96 |
| Space group | C 1 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 113.000, 219.560, 107.520, 90.00, 102.02, 90.00 |
| R / Rfree (%) | 18.4 / 21.3 |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Phers in Complex with Compound 4A
(pdb code 4p75). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 6 binding sites of Fluorine where determined in the Phers in Complex with Compound 4A, PDB code: 4p75:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6;
In total 6 binding sites of Fluorine where determined in the Phers in Complex with Compound 4A, PDB code: 4p75:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6;
Fluorine binding site 1 out of 6 in 4p75
Go back to
Fluorine Binding Sites List in 4p75
Fluorine binding site 1 out
of 6 in the Phers in Complex with Compound 4A
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Phers in Complex with Compound 4A within 5.0Å range:
|
Fluorine binding site 2 out of 6 in 4p75
Go back to
Fluorine Binding Sites List in 4p75
Fluorine binding site 2 out
of 6 in the Phers in Complex with Compound 4A
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Phers in Complex with Compound 4A within 5.0Å range:
|
Fluorine binding site 3 out of 6 in 4p75
Go back to
Fluorine Binding Sites List in 4p75
Fluorine binding site 3 out
of 6 in the Phers in Complex with Compound 4A
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Phers in Complex with Compound 4A within 5.0Å range:
|
Fluorine binding site 4 out of 6 in 4p75
Go back to
Fluorine Binding Sites List in 4p75
Fluorine binding site 4 out
of 6 in the Phers in Complex with Compound 4A
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Phers in Complex with Compound 4A within 5.0Å range:
|
Fluorine binding site 5 out of 6 in 4p75
Go back to
Fluorine Binding Sites List in 4p75
Fluorine binding site 5 out
of 6 in the Phers in Complex with Compound 4A
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 5 of Phers in Complex with Compound 4A within 5.0Å range:
|
Fluorine binding site 6 out of 6 in 4p75
Go back to
Fluorine Binding Sites List in 4p75
Fluorine binding site 6 out
of 6 in the Phers in Complex with Compound 4A
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 6 of Phers in Complex with Compound 4A within 5.0Å range:
|
Reference:
A.Abibi,
A.D.Ferguson,
P.R.Fleming,
N.Gao,
L.I.Hajec,
J.Hu,
V.A.Laganas,
D.C.Mckinney,
S.M.Mcleod,
D.B.Prince,
A.B.Shapiro,
E.T.Buurman.
The Role of A Novel Auxiliary Pocket in Bacterial Phenylalanyl-Trna Synthetase Druggability. J.Biol.Chem. V. 289 21651 2014.
ISSN: ESSN 1083-351X
PubMed: 24936059
DOI: 10.1074/JBC.M114.574061
Page generated: Tue Jul 15 00:01:35 2025
ISSN: ESSN 1083-351X
PubMed: 24936059
DOI: 10.1074/JBC.M114.574061
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