Fluorine in PDB 4tyi: Structural Analysis of the Human Fibroblast Growth Factor Receptor 4

All present enzymatic activity of Structural Analysis of the Human Fibroblast Growth Factor Receptor 4:
2.7.10.1;

The structure of Structural Analysis of the Human Fibroblast Growth Factor Receptor 4, PDB code: 4tyi was solved by E.Lesca, A.Lammens, R.Huber, M.Augustin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	61.97 / 3.40
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	65.900, 65.900, 182.262, 90.00, 90.00, 90.00
R / Rfree (%)	27.7 / 34

The binding sites of Fluorine atom in the Structural Analysis of the Human Fibroblast Growth Factor Receptor 4 (pdb code 4tyi). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Structural Analysis of the Human Fibroblast Growth Factor Receptor 4, PDB code: 4tyi:

Fluorine binding site 1 out of 1 in the Structural Analysis of the Human Fibroblast Growth Factor Receptor 4


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structural Analysis of the Human Fibroblast Growth Factor Receptor 4 within 5.0Å range: probe atom residue distance (Å) B Occ A:F801 b:0.9 occ:1.00 F22 A:38O801 0.0 0.9 1.0 C21 A:38O801 1.4 0.9 1.0 C23 A:38O801 2.4 0.5 1.0 C20 A:38O801 2.4 1.0 1.0 N19 A:38O801 2.6 1.0 1.0 C18 A:38O801 2.9 0.8 1.0 C24 A:38O801 3.6 0.5 1.0 C26 A:38O801 3.7 0.9 1.0 CG2 A:VAL481 3.9 0.3 1.0 C25 A:38O801 4.1 0.0 1.0 C17 A:38O801 4.3 0.9 1.0 CB A:VAL481 4.6 0.2 1.0 OD1 A:ASP630 4.6 0.5 1.0 CG1 A:VAL481 4.7 0.8 1.0 N27 A:38O801 4.8 0.9 1.0 CD1 A:LEU619 4.9 0.3 1.0

E.Lesca, A.Lammens, R.Huber, M.Augustin. Structural Analysis of the Human Fibroblast Growth Factor Receptor 4 Kinase. J.Mol.Biol. 2014.
ISSN: ESSN 1089-8638
PubMed: 25219510
DOI: 10.1016/J.JMB.2014.09.004