Fluorine in PDB 5ci3: Ribonucleotide Reductase Y122 2,3,5-F3Y Variant
Enzymatic activity of Ribonucleotide Reductase Y122 2,3,5-F3Y Variant
All present enzymatic activity of Ribonucleotide Reductase Y122 2,3,5-F3Y Variant:
1.17.4.1;
Protein crystallography data
The structure of Ribonucleotide Reductase Y122 2,3,5-F3Y Variant, PDB code: 5ci3
was solved by
M.A.Funk,
C.L.Drennan,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
43.44 /
2.40
|
|
Space group
|
P 61 2 2
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
92.216,
92.216,
207.044,
90.00,
90.00,
120.00
|
|
R / Rfree (%)
|
16.6 /
21.2
|
Other elements in 5ci3:
The structure of Ribonucleotide Reductase Y122 2,3,5-F3Y Variant also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Ribonucleotide Reductase Y122 2,3,5-F3Y Variant
(pdb code 5ci3). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 6 binding sites of Fluorine where determined in the
Ribonucleotide Reductase Y122 2,3,5-F3Y Variant, PDB code: 5ci3:
Jump to Fluorine binding site number:
1;
2;
3;
4;
5;
6;
Fluorine binding site 1 out
of 6 in 5ci3
Go back to
Fluorine Binding Sites List in 5ci3
Fluorine binding site 1 out
of 6 in the Ribonucleotide Reductase Y122 2,3,5-F3Y Variant
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Ribonucleotide Reductase Y122 2,3,5-F3Y Variant within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F122
b:91.9
occ:0.55
|
F2
|
A:FY3122
|
0.0
|
91.9
|
0.6
|
|
CD2
|
A:FY3122
|
1.0
|
87.0
|
0.5
|
|
CD1
|
A:FY3122
|
1.3
|
86.7
|
0.6
|
|
CE2
|
A:FY3122
|
2.0
|
85.4
|
0.5
|
|
CG
|
A:FY3122
|
2.2
|
85.4
|
0.5
|
|
CE1
|
A:FY3122
|
2.3
|
85.8
|
0.6
|
|
CG
|
A:FY3122
|
2.3
|
84.4
|
0.6
|
|
F5
|
A:FY3122
|
2.4
|
81.9
|
0.5
|
|
F3
|
A:FY3122
|
2.7
|
83.9
|
0.6
|
|
CB
|
A:FY3122
|
2.8
|
77.1
|
0.6
|
|
CB
|
A:FY3122
|
2.8
|
78.7
|
0.5
|
|
CD1
|
A:LEU77
|
2.9
|
92.3
|
1.0
|
|
CA
|
A:FY3122
|
3.0
|
74.8
|
0.5
|
|
CA
|
A:FY3122
|
3.0
|
74.6
|
0.6
|
|
CZ
|
A:FY3122
|
3.2
|
85.7
|
0.5
|
|
CD1
|
A:FY3122
|
3.3
|
86.7
|
0.5
|
|
CD1
|
A:ILE125
|
3.4
|
68.3
|
1.0
|
|
CZ
|
A:FY3122
|
3.6
|
85.6
|
0.6
|
|
CD2
|
A:FY3122
|
3.6
|
86.8
|
0.6
|
|
CE1
|
A:FY3122
|
3.7
|
86.4
|
0.5
|
|
N
|
A:FY3122
|
3.8
|
70.3
|
0.5
|
|
N
|
A:FY3122
|
3.8
|
69.7
|
0.6
|
|
CE2
|
A:FY3122
|
4.1
|
87.2
|
0.6
|
|
CG
|
A:LEU77
|
4.1
|
89.5
|
1.0
|
|
C
|
A:FY3122
|
4.2
|
78.6
|
0.5
|
|
C
|
A:FY3122
|
4.2
|
79.0
|
0.6
|
|
OH
|
A:FY3122
|
4.3
|
85.6
|
0.5
|
|
O
|
A:FY3122
|
4.4
|
80.5
|
0.5
|
|
O
|
A:FY3122
|
4.4
|
80.7
|
0.6
|
|
C
|
A:SER121
|
4.4
|
69.7
|
1.0
|
|
OG1
|
A:THR81
|
4.5
|
73.6
|
1.0
|
|
O
|
A:SER121
|
4.5
|
71.6
|
1.0
|
|
F2
|
A:FY3122
|
4.5
|
88.6
|
0.5
|
|
CG1
|
A:ILE125
|
4.6
|
71.7
|
1.0
|
|
CB
|
A:ILE125
|
4.6
|
73.1
|
1.0
|
|
OH
|
A:FY3122
|
4.7
|
86.3
|
0.6
|
|
OG
|
A:SER121
|
4.8
|
73.9
|
1.0
|
|
OD1
|
A:ASN227
|
4.8
|
81.5
|
1.0
|
|
OE1
|
A:GLN80
|
4.8
|
93.1
|
1.0
|
|
CD2
|
A:LEU77
|
4.9
|
90.3
|
1.0
|
|
O
|
A:LEU77
|
4.9
|
75.5
|
1.0
|
|
O
|
A:HOH542
|
4.9
|
85.9
|
1.0
|
|
Fluorine binding site 2 out
of 6 in 5ci3
Go back to
Fluorine Binding Sites List in 5ci3
Fluorine binding site 2 out
of 6 in the Ribonucleotide Reductase Y122 2,3,5-F3Y Variant
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Ribonucleotide Reductase Y122 2,3,5-F3Y Variant within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F122
b:88.6
occ:0.45
|
F2
|
A:FY3122
|
0.0
|
88.6
|
0.5
|
|
CD2
|
A:FY3122
|
1.0
|
86.8
|
0.6
|
|
CD1
|
A:FY3122
|
1.3
|
86.7
|
0.5
|
|
CE2
|
A:FY3122
|
1.9
|
87.2
|
0.6
|
|
CG
|
A:FY3122
|
2.2
|
84.4
|
0.6
|
|
F5
|
A:FY3122
|
2.3
|
91.3
|
0.6
|
|
CE1
|
A:FY3122
|
2.4
|
86.4
|
0.5
|
|
CG
|
A:FY3122
|
2.4
|
85.4
|
0.5
|
|
F3
|
A:FY3122
|
2.7
|
88.5
|
0.5
|
|
CB
|
A:FY3122
|
2.9
|
78.7
|
0.5
|
|
CB
|
A:FY3122
|
2.9
|
77.1
|
0.6
|
|
CA
|
A:SER119
|
3.1
|
73.1
|
0.6
|
|
CA
|
A:SER119
|
3.1
|
73.6
|
0.4
|
|
CZ
|
A:FY3122
|
3.2
|
85.6
|
0.6
|
|
O
|
A:HIS118
|
3.3
|
74.4
|
1.0
|
|
CD1
|
A:FY3122
|
3.3
|
86.7
|
0.6
|
|
CA
|
A:THR81
|
3.4
|
82.0
|
1.0
|
|
O
|
A:SER119
|
3.6
|
75.8
|
0.6
|
|
O
|
A:SER119
|
3.6
|
75.4
|
0.4
|
|
CZ
|
A:FY3122
|
3.6
|
85.7
|
0.5
|
|
CD2
|
A:FY3122
|
3.6
|
87.0
|
0.5
|
|
N
|
A:SER119
|
3.7
|
72.6
|
0.6
|
|
N
|
A:SER119
|
3.7
|
72.8
|
0.4
|
|
CE1
|
A:FY3122
|
3.7
|
85.8
|
0.6
|
|
C
|
A:HIS118
|
3.8
|
72.7
|
1.0
|
|
C
|
A:SER119
|
3.8
|
74.5
|
0.6
|
|
C
|
A:SER119
|
3.8
|
74.1
|
0.4
|
|
CG2
|
A:THR81
|
3.8
|
76.3
|
1.0
|
|
OG1
|
A:THR81
|
3.8
|
73.6
|
1.0
|
|
CB
|
A:THR81
|
3.9
|
78.7
|
1.0
|
|
CB
|
A:SER119
|
4.0
|
75.2
|
0.6
|
|
CB
|
A:SER119
|
4.1
|
75.6
|
0.4
|
|
CE2
|
A:FY3122
|
4.1
|
85.4
|
0.5
|
|
CA
|
A:FY3122
|
4.1
|
74.8
|
0.5
|
|
OG
|
A:SER119
|
4.1
|
78.0
|
0.6
|
|
CA
|
A:FY3122
|
4.1
|
74.6
|
0.6
|
|
N
|
A:FY3122
|
4.2
|
70.3
|
0.5
|
|
N
|
A:THR81
|
4.2
|
76.9
|
1.0
|
|
N
|
A:FY3122
|
4.2
|
69.7
|
0.6
|
|
OH
|
A:FY3122
|
4.3
|
86.3
|
0.6
|
|
O
|
A:THR81
|
4.3
|
81.5
|
1.0
|
|
O
|
A:GLN80
|
4.3
|
82.8
|
1.0
|
|
C
|
A:THR81
|
4.4
|
85.0
|
1.0
|
|
F2
|
A:FY3122
|
4.5
|
91.9
|
0.6
|
|
O
|
A:HOH537
|
4.5
|
69.2
|
1.0
|
|
C
|
A:GLN80
|
4.5
|
76.2
|
1.0
|
|
CB
|
A:ASP84
|
4.5
|
70.3
|
1.0
|
|
OH
|
A:FY3122
|
4.7
|
85.6
|
0.5
|
|
N
|
A:ARG120
|
5.0
|
68.4
|
1.0
|
|
Fluorine binding site 3 out
of 6 in 5ci3
Go back to
Fluorine Binding Sites List in 5ci3
Fluorine binding site 3 out
of 6 in the Ribonucleotide Reductase Y122 2,3,5-F3Y Variant
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Ribonucleotide Reductase Y122 2,3,5-F3Y Variant within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F122
b:83.9
occ:0.55
|
F3
|
A:FY3122
|
0.0
|
83.9
|
0.6
|
|
F5
|
A:FY3122
|
0.7
|
81.9
|
0.5
|
|
CE2
|
A:FY3122
|
1.1
|
85.4
|
0.5
|
|
CE1
|
A:FY3122
|
1.3
|
85.8
|
0.6
|
|
CZ
|
A:FY3122
|
1.7
|
85.7
|
0.5
|
|
OH
|
A:FY3122
|
2.0
|
85.6
|
0.5
|
|
CD1
|
A:FY3122
|
2.4
|
86.7
|
0.6
|
|
CZ
|
A:FY3122
|
2.4
|
85.6
|
0.6
|
|
CD2
|
A:FY3122
|
2.4
|
87.0
|
0.5
|
|
F2
|
A:FY3122
|
2.7
|
91.9
|
0.6
|
|
OH
|
A:FY3122
|
2.8
|
86.3
|
0.6
|
|
CE1
|
A:FY3122
|
3.1
|
86.4
|
0.5
|
|
NE2
|
A:GLN80
|
3.2
|
87.5
|
1.0
|
|
CD
|
A:GLN80
|
3.4
|
87.0
|
1.0
|
|
CD1
|
A:ILE231
|
3.5
|
73.2
|
1.0
|
|
CG
|
A:FY3122
|
3.5
|
85.4
|
0.5
|
|
OE1
|
A:GLN80
|
3.6
|
93.1
|
1.0
|
|
CE2
|
A:FY3122
|
3.6
|
87.2
|
0.6
|
|
CG
|
A:FY3122
|
3.6
|
84.4
|
0.6
|
|
CD1
|
A:ILE234
|
3.7
|
62.6
|
1.0
|
|
CD1
|
A:FY3122
|
3.7
|
86.7
|
0.5
|
|
CB
|
A:GLN80
|
3.8
|
72.2
|
1.0
|
|
F3
|
A:FY3122
|
4.1
|
88.5
|
0.5
|
|
CD2
|
A:FY3122
|
4.1
|
86.8
|
0.6
|
|
CG
|
A:GLN80
|
4.2
|
78.0
|
1.0
|
|
O
|
A:HOH542
|
4.3
|
85.9
|
1.0
|
|
CD1
|
A:LEU77
|
4.4
|
92.3
|
1.0
|
|
F5
|
A:FY3122
|
4.7
|
91.3
|
0.6
|
|
CB
|
A:FY3122
|
4.8
|
78.7
|
0.5
|
|
O
|
A:HOH508
|
4.9
|
0.8
|
1.0
|
|
CB
|
A:FY3122
|
4.9
|
77.1
|
0.6
|
|
CD1
|
A:ILE125
|
4.9
|
68.3
|
1.0
|
|
CG1
|
A:ILE231
|
5.0
|
71.5
|
1.0
|
|
Fluorine binding site 4 out
of 6 in 5ci3
Go back to
Fluorine Binding Sites List in 5ci3
Fluorine binding site 4 out
of 6 in the Ribonucleotide Reductase Y122 2,3,5-F3Y Variant
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Ribonucleotide Reductase Y122 2,3,5-F3Y Variant within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F122
b:88.5
occ:0.45
|
F3
|
A:FY3122
|
0.0
|
88.5
|
0.5
|
|
F5
|
A:FY3122
|
0.9
|
91.3
|
0.6
|
|
CE2
|
A:FY3122
|
1.3
|
87.2
|
0.6
|
|
CE1
|
A:FY3122
|
1.3
|
86.4
|
0.5
|
|
CZ
|
A:FY3122
|
1.8
|
85.6
|
0.6
|
|
OH
|
A:FY3122
|
2.0
|
86.3
|
0.6
|
|
CZ
|
A:FY3122
|
2.3
|
85.7
|
0.5
|
|
CD1
|
A:FY3122
|
2.4
|
86.7
|
0.5
|
|
CD2
|
A:FY3122
|
2.6
|
86.8
|
0.6
|
|
F2
|
A:FY3122
|
2.7
|
88.6
|
0.5
|
|
OH
|
A:FY3122
|
2.7
|
85.6
|
0.5
|
|
CE1
|
A:FY3122
|
3.1
|
85.8
|
0.6
|
|
O
|
A:GLN80
|
3.1
|
82.8
|
1.0
|
|
CB
|
A:ASP84
|
3.2
|
70.3
|
1.0
|
|
OD2
|
A:ASP84
|
3.3
|
64.9
|
1.0
|
|
CG
|
A:ASP84
|
3.6
|
72.0
|
1.0
|
|
CG
|
A:FY3122
|
3.6
|
84.4
|
0.6
|
|
CE2
|
A:FY3122
|
3.6
|
85.4
|
0.5
|
|
CG
|
A:FY3122
|
3.6
|
85.4
|
0.5
|
|
C
|
A:GLN80
|
3.7
|
76.2
|
1.0
|
|
CD1
|
A:FY3122
|
3.8
|
86.7
|
0.6
|
|
CB
|
A:HIS118
|
4.0
|
60.7
|
1.0
|
|
F3
|
A:FY3122
|
4.1
|
83.9
|
0.6
|
|
O
|
A:HIS118
|
4.1
|
74.4
|
1.0
|
|
CD2
|
A:FY3122
|
4.1
|
87.0
|
0.5
|
|
CB
|
A:GLN80
|
4.2
|
72.2
|
1.0
|
|
CZ
|
A:PHE208
|
4.2
|
81.2
|
1.0
|
|
N
|
A:THR81
|
4.2
|
76.9
|
1.0
|
|
C
|
A:HIS118
|
4.2
|
72.7
|
1.0
|
|
CA
|
A:THR81
|
4.2
|
82.0
|
1.0
|
|
CE1
|
A:PHE208
|
4.4
|
80.1
|
1.0
|
|
CA
|
A:ASP84
|
4.4
|
75.7
|
1.0
|
|
CA
|
A:GLN80
|
4.5
|
72.1
|
1.0
|
|
N
|
A:SER119
|
4.5
|
72.6
|
0.6
|
|
N
|
A:SER119
|
4.5
|
72.8
|
0.4
|
|
N
|
A:ASP84
|
4.5
|
70.9
|
1.0
|
|
OD1
|
A:ASP84
|
4.7
|
75.7
|
1.0
|
|
F5
|
A:FY3122
|
4.7
|
81.9
|
0.5
|
|
CA
|
A:HIS118
|
4.7
|
67.2
|
1.0
|
|
CA
|
A:SER119
|
4.7
|
73.1
|
0.6
|
|
CA
|
A:SER119
|
4.7
|
73.6
|
0.4
|
|
CD1
|
A:ILE234
|
4.8
|
62.6
|
1.0
|
|
O
|
A:HOH561
|
4.9
|
89.8
|
1.0
|
|
CB
|
A:FY3122
|
4.9
|
78.7
|
0.5
|
|
C
|
A:THR81
|
5.0
|
85.0
|
1.0
|
|
CB
|
A:FY3122
|
5.0
|
77.1
|
0.6
|
|
O
|
A:THR81
|
5.0
|
81.5
|
1.0
|
|
Fluorine binding site 5 out
of 6 in 5ci3
Go back to
Fluorine Binding Sites List in 5ci3
Fluorine binding site 5 out
of 6 in the Ribonucleotide Reductase Y122 2,3,5-F3Y Variant
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 5 of Ribonucleotide Reductase Y122 2,3,5-F3Y Variant within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F122
b:91.3
occ:0.55
|
F5
|
A:FY3122
|
0.0
|
91.3
|
0.6
|
|
F3
|
A:FY3122
|
0.9
|
88.5
|
0.5
|
|
CE2
|
A:FY3122
|
1.3
|
87.2
|
0.6
|
|
CE1
|
A:FY3122
|
1.8
|
86.4
|
0.5
|
|
CD1
|
A:FY3122
|
2.3
|
86.7
|
0.5
|
|
CZ
|
A:FY3122
|
2.3
|
85.6
|
0.6
|
|
F2
|
A:FY3122
|
2.3
|
88.6
|
0.5
|
|
CD2
|
A:FY3122
|
2.3
|
86.8
|
0.6
|
|
OH
|
A:FY3122
|
2.7
|
86.3
|
0.6
|
|
CB
|
A:ASP84
|
2.9
|
70.3
|
1.0
|
|
CZ
|
A:FY3122
|
3.0
|
85.7
|
0.5
|
|
OD2
|
A:ASP84
|
3.2
|
64.9
|
1.0
|
|
C
|
A:HIS118
|
3.4
|
72.7
|
1.0
|
|
CB
|
A:HIS118
|
3.5
|
60.7
|
1.0
|
|
O
|
A:HIS118
|
3.5
|
74.4
|
1.0
|
|
CG
|
A:ASP84
|
3.5
|
72.0
|
1.0
|
|
OH
|
A:FY3122
|
3.5
|
85.6
|
0.5
|
|
CG
|
A:FY3122
|
3.6
|
84.4
|
0.6
|
|
CE1
|
A:FY3122
|
3.6
|
85.8
|
0.6
|
|
N
|
A:SER119
|
3.6
|
72.6
|
0.6
|
|
N
|
A:SER119
|
3.6
|
72.8
|
0.4
|
|
CG
|
A:FY3122
|
3.7
|
85.4
|
0.5
|
|
O
|
A:GLN80
|
3.7
|
82.8
|
1.0
|
|
CA
|
A:SER119
|
3.8
|
73.1
|
0.6
|
|
CA
|
A:SER119
|
3.8
|
73.6
|
0.4
|
|
CA
|
A:HIS118
|
4.0
|
67.2
|
1.0
|
|
CD1
|
A:FY3122
|
4.1
|
86.7
|
0.6
|
|
CE2
|
A:FY3122
|
4.1
|
85.4
|
0.5
|
|
CA
|
A:ASP84
|
4.2
|
75.7
|
1.0
|
|
OG
|
A:SER119
|
4.3
|
78.0
|
0.6
|
|
C
|
A:GLN80
|
4.3
|
76.2
|
1.0
|
|
CD2
|
A:FY3122
|
4.4
|
87.0
|
0.5
|
|
CA
|
A:THR81
|
4.4
|
82.0
|
1.0
|
|
N
|
A:ASP84
|
4.6
|
70.9
|
1.0
|
|
OD1
|
A:ASP84
|
4.7
|
75.7
|
1.0
|
|
CB
|
A:SER119
|
4.7
|
75.2
|
0.6
|
|
N
|
A:THR81
|
4.7
|
76.9
|
1.0
|
|
F3
|
A:FY3122
|
4.7
|
83.9
|
0.6
|
|
CG
|
A:HIS118
|
4.7
|
62.8
|
1.0
|
|
CB
|
A:SER119
|
4.7
|
75.6
|
0.4
|
|
CB
|
A:FY3122
|
4.8
|
78.7
|
0.5
|
|
C
|
A:ASP84
|
4.8
|
81.2
|
1.0
|
|
CZ
|
A:PHE208
|
4.8
|
81.2
|
1.0
|
|
CB
|
A:FY3122
|
4.8
|
77.1
|
0.6
|
|
O
|
A:THR81
|
4.9
|
81.5
|
1.0
|
|
C
|
A:SER119
|
5.0
|
74.5
|
0.6
|
|
C
|
A:SER119
|
5.0
|
74.1
|
0.4
|
|
O
|
A:GLU115
|
5.0
|
69.9
|
1.0
|
|
CD1
|
A:ILE234
|
5.0
|
62.6
|
1.0
|
|
Fluorine binding site 6 out
of 6 in 5ci3
Go back to
Fluorine Binding Sites List in 5ci3
Fluorine binding site 6 out
of 6 in the Ribonucleotide Reductase Y122 2,3,5-F3Y Variant
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 6 of Ribonucleotide Reductase Y122 2,3,5-F3Y Variant within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F122
b:81.9
occ:0.45
|
F5
|
A:FY3122
|
0.0
|
81.9
|
0.5
|
|
F3
|
A:FY3122
|
0.7
|
83.9
|
0.6
|
|
CE2
|
A:FY3122
|
1.3
|
85.4
|
0.5
|
|
CE1
|
A:FY3122
|
1.8
|
85.8
|
0.6
|
|
CZ
|
A:FY3122
|
2.4
|
85.7
|
0.5
|
|
CD2
|
A:FY3122
|
2.4
|
87.0
|
0.5
|
|
F2
|
A:FY3122
|
2.4
|
91.9
|
0.6
|
|
CD1
|
A:FY3122
|
2.4
|
86.7
|
0.6
|
|
OH
|
A:FY3122
|
2.7
|
85.6
|
0.5
|
|
CZ
|
A:FY3122
|
3.0
|
85.6
|
0.6
|
|
CD1
|
A:ILE231
|
3.1
|
73.2
|
1.0
|
|
OH
|
A:FY3122
|
3.5
|
86.3
|
0.6
|
|
NE2
|
A:GLN80
|
3.5
|
87.5
|
1.0
|
|
CE1
|
A:FY3122
|
3.6
|
86.4
|
0.5
|
|
CG
|
A:FY3122
|
3.6
|
85.4
|
0.5
|
|
OE1
|
A:GLN80
|
3.7
|
93.1
|
1.0
|
|
CD
|
A:GLN80
|
3.7
|
87.0
|
1.0
|
|
CG
|
A:FY3122
|
3.8
|
84.4
|
0.6
|
|
CD1
|
A:ILE234
|
3.8
|
62.6
|
1.0
|
|
O
|
A:HOH542
|
4.0
|
85.9
|
1.0
|
|
CD1
|
A:LEU77
|
4.1
|
92.3
|
1.0
|
|
CD1
|
A:FY3122
|
4.1
|
86.7
|
0.5
|
|
CE2
|
A:FY3122
|
4.1
|
87.2
|
0.6
|
|
CD1
|
A:ILE125
|
4.2
|
68.3
|
1.0
|
|
CB
|
A:GLN80
|
4.4
|
72.2
|
1.0
|
|
CD2
|
A:FY3122
|
4.5
|
86.8
|
0.6
|
|
CG1
|
A:ILE231
|
4.6
|
71.5
|
1.0
|
|
OD1
|
A:ASN227
|
4.6
|
81.5
|
1.0
|
|
CG
|
A:GLN80
|
4.7
|
78.0
|
1.0
|
|
F3
|
A:FY3122
|
4.7
|
88.5
|
0.5
|
|
CB
|
A:FY3122
|
4.8
|
78.7
|
0.5
|
|
CB
|
A:FY3122
|
4.9
|
77.1
|
0.6
|
|
O
|
A:HOH508
|
4.9
|
0.8
|
1.0
|
|
OG
|
A:SER121
|
4.9
|
73.9
|
1.0
|
|
Reference:
P.H.Oyala,
K.R.Ravichandran,
M.A.Funk,
P.A.Stucky,
T.A.Stich,
C.L.Drennan,
R.D.Britt,
J.Stubbe.
Biophysical Characterization of Fluorotyrosine Probes Site-Specifically Incorporated Into Enzymes: E. Coli Ribonucleotide Reductase As An Example. J.Am.Chem.Soc. V. 138 7951 2016.
ISSN: ESSN 1520-5126
PubMed: 27276098
DOI: 10.1021/JACS.6B03605
Page generated: Tue Jul 15 02:52:19 2025
|
